scholarly journals The relationship between serum vitamin D and fracture risk in the elderly: a meta-analysis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Ning Wang ◽  
Yungang Chen ◽  
Jindou Ji ◽  
Jinlei Chang ◽  
Shengwen Yu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Fracture Risk ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
The Elderly ◽  
Serum Vitamin D ◽  
The Relationship

THE RELATIONSHIP OF VITAMIN D 25(OH)D LEVELS WITH THE INCIDENCE OF HYPERTENSION ON THE ELDERLY AT PUBLIC HEALTH CLINIC

2020 ◽  
Vol 1 (2) ◽  
pp. 9-12
Author(s):  
Ikram S. Akbar ◽  
Irfan K. Pratama ◽  
Achmad Zaki ◽  
Sayyid Ridho ◽  
Dede Moeswir ◽  
...  
Keyword(s):  
Public Health ◽  
Vitamin D ◽  
Serum Vitamin ◽  
The Elderly ◽  
Health Clinic ◽  
Anthropometric Measurement ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
The Relationship ◽  
Public Health Clinic

Introduction: Hypertension is a chronic disease which its presence is often not known until occurrence of other diseases. Several studies had previously investigated the relationship between vitamin D concentration and hypertension. However, no concluding result is obtained. This paper aimed to determine the relationship between vitamin D 25(OH)D concentration and hypertension onelderly at a public health clinic located at Reni Jaya, South Tangerang.Methods: This was cross-sectional study conducted in a public health clinic between January 2017 to January 2018. One hundred and fifty subjects were recruited by consecutive sampling after informed consent were obtained.Anamnesis, physical examination, and anthropometric measurement were performed by general practitioners. The following day serum vitamin D 25(OH)D examination were collected and examined at certied laboratory. The data werethen analyzed using Chi-Square test.Results : As many as 80 (53.4%) subjects had insufficient vitamin D 25(OH)D concentration (25-50 nmol/L). Stage I and II hypertension were found in 51 (34.0%) and 34 (22.7%) subjects, respectively. Age was significantly associated with hypertension (p=0.048). No significant association was observed between vitamin D 25 (OH)D and hypertension p=0.347.Conclusions: There was no significant association between serum vitamin D 25(OH)D and hypertension.

The association between vitamin D levels and precocious puberty: a meta-analysis

2020 ◽  
Vol 33 (3) ◽  
pp. 427-429
Author(s):  
Shanshan Liu ◽  
Xun Zhu ◽  
Yuanxin Wang ◽  
Shoumeng Yan ◽  
Dong Li ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Precocious Puberty ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Comprehensive Search ◽  
Vitamin D Supplements ◽  
The Relationship

AbstractThe objective of this short communication was the relationship between vitamin D and precocious puberty (PP). In this study, a comprehensive search of multiple databases was performed to identify studies focused on the association between vitamin D deficiency and PP. Studies that compared serum vitamin D levels between patients with PP and controls were selected for the systematic meta-analysis. The main outcome was the mean difference in serum vitamin D levels between PP and controls. Vitamin D-deficient subjects were more likely to develop PP. Our findings suggest that PP may be linked to vitamin D deficiency. Thus, providing supplements of vitamin D to PP patients may improve their nutritional status and prevent diseases. But, the amount of vitamin D required is uncertain, so it is important to be careful when taking vitamin D supplements.

scholarly journals The relationship between vitamin D and risk of atrial fibrillation: a dose-response analysis of observational studies

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Xiao Liu ◽  
Wei Wang ◽  
Zhaochong Tan ◽  
Xin Zhu ◽  
Menglu Liu ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Dose Response ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Cochrane Library ◽  
Response Analysis ◽  
Serum Vitamin D ◽  
The Relationship

Abstract Background The relationship between serum vitamin D and atrial fibrillation (AF) or postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass graft (CABG) is still debated. It is also unclear whether there is a dose-response relationship between circulating vitamin D and the risk of AF or POAF. Methods The Cochrane Library, PubMed, and Embase databases were searched for relevant studies. We used a “one-stage approach” with a restricted cubic spline model to summarize the dose-specific relationships between serum vitamin D and AF. Relative risk (RR) was used to measure the effects in this meta-analysis. Results In total, 13 studies were included with a total of 6519 cases of AF among 74,885 participants. Vitamin D deficiency (< 20 ng/ml) was associated with increased risks of AF (RR: 1.23, 95% CI: 1.05–1.43). In the dose-response analysis, the summary RR for a 10 ng/ml increased in vitamin D was 0.88 (95% CI: 0.78–0.98) and there was no evidence of a non-linear association, Pnon-linearity = 0.86. In the age subgroup, high vitamin D (per 10 ng/ml increase) reduced the risk of AF in the older group (> 65 years) (RR = 0.68, 95% CI = 0.52–0.89) but not among young individuals (< 65 years) (RR = 0.87, 95% CI = 0.72–1.06). In addition, a strong association was found between a 10 ng/ml increased in vitamin D and POAF incident in the patient after CABG (RR: 0.44, 95% CI: 0.24–0.82). Conclusion Our dose-response meta-analysis suggested serum vitamin D deficiency was associated with an increased risk of AF in the general population and POAF in patients after CABG. Further studies are needed to explore the age difference in the association between serum vitamin D level and the risk of AF and whether vitamin D supplements will prevent AF. Trial registration This study has been registered with PROSPERO (International prospective register of systematic reviews)-registration number-CRD42019119258.

scholarly journals The relationship between preoperative serum vitamin D deficiency and postoperative atrial fibrillation: A systematic review and meta-analysis

2021 ◽  
Vol 13 (2) ◽  
pp. 102-108
Author(s):  
Mehran Rahimi ◽  
Mohammadreza Taban-Sadeghi ◽  
Leila Nikniaz ◽  
Fariba Pashazadeh
Keyword(s):  
Atrial Fibrillation ◽  
Systematic Review ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Postoperative Atrial Fibrillation ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Relationship

Postoperative atrial fibrillation (POAF) is the most common arrhythmia seen in the first days following cardiac surgeries. Recently, there is a growing discussion regarding the link between vitamin D deficiency and POAF development. This systematic review and meta-analysis of the observational studies aimed at evaluating the association between preoperative vitamin D deficiency and Postoperative atrial fibrillation. In this study, using PubMed, Scopus, Google Scholar, EMBASE, Web of Science, and Cochrane Libraries, we searched for records published before July 2020. Two reviewers screened for studies that examined the relationship between preoperative vitamin D levels and the generation of POAF. Data regarding study design, patient characteristics, definition of atrial fibrillation (AF) , type of surgery, vitamin D levels, and measurement methods were extracted. Five studies were included in the meta-analysis. Our primary analysis showed a significant relationship between preoperative levels of vitamin D and POAF development (mean differences (MD) = -2.851, 95% confidence interval (CI) =-5.506 to -0.195; P value 0.035). Our meta-analysis suggested serum vitamin D deficiency is associated with an increased risk of POAF development. Further large scale interventional studies are needed to explore whether vitamin D supplementation will prevent POAF.

Serum vitamin D levels in females with urinary incontinence: a meta-analysis of observational trials

2021 ◽  
Author(s):  
Chih-Chen Hsu ◽  
Yu-Chen Huang ◽  
Syuan-Hao Syu ◽  
Hung-Jen Shih ◽  
Yung-Wei Lin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Urinary Incontinence ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Causal analysis shows evidence of atopic dermatitis leading to an increase in vitamin D levels

2020 ◽  
Author(s):  
Daniel R Drodge ◽  
Ashley Budu-Aggrey ◽  
Lavinia Paternoster
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Serum Vitamin ◽  
Strong Relationship ◽  
Reverse Direction ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Standard Deviations ◽  
The Relationship ◽  
Gwa Studies

AbstractAtopic dermatitis (AD) patients have been observed to have lower vitamin D levels. Previous studies have found little evidence that vitamin D levels causally influence the risk of AD, but the reverse direction has not yet been investigated.Here we used Mendelian Randomization to assess the causal relationship between AD and serum vitamin D levels, using genetic data from the most recent GWA studies of vitamin D and AD.There was little evidence for vitamin D levels causally influencing AD risk (odds per standard deviations increase in log-transformed vitamin D levels =1.233, 95% CI 0.927 to 1.639, P-value =0.150). However, genetic liability for AD raises serum vitamin D levels by 0.043 (95% CI 0.017 to 0.069) standard deviations per doubling of odds of disease (P-value =0.001). The AD-associated filaggrin (FLG) mutation R501X appears to show a particularly strong relationship with vitamin D. However, the relationship between AD and vitamin D holds when R501X is omitted (0.018, 95% CI 0.004 to 0.031, P-value =0.008).We found evidence that AD is causally associated with an increase in serum vitamin D levels. Whilst the AD-associated FLG gene has a particularly strong relationship with vitamin D, other AD SNPs show a consistent direction of effect, suggesting that AD more generally influences serum vitamin D levels.

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