A preclinical animal model for evaluating the sealing capacity of covered stent grafts in acute vessel perforation

Purpose To evaluate the safety and efficacy of transbrachial and transfemoral approaches combined with visceral protection for the endovascular treatment of juxtarenal aortoiliac occlusive disease (AIOD) over an average 19-month follow-up period. Methods In this retrospective analysis, all patients with juxtarenal AIOD at a single institution were reviewed from June 2015 to January 2020. Patient characteristics, angiographic results, and follow-up outcomes were retrospectively recorded. The indications for treatment were critical limb threatening ischemia in 12 patients and bilateral claudication in five patients. Percutaneous access via the left brachial artery was first obtained to recanalize the infrarenal occluded lesions. After that, femoral accesses were achieved. A 4-Fr catheter, a 4 mm balloon, or a 6-Fr 90-cm-long sheath was used to complete visceral artery protection. Results A total of 17 juxtarenal AIOD patients (14 males; mean age, 63.4 ± 8.1 years) underwent endovascular treatment. The technical success rate was 100%. Complete reconstruction was achieved in 15 (88.2%) patients. The infrarenal aorta was reconstructed with kissing covered stent grafts ( n = 7), kissing bare-metal stents ( n = 2), covered stent grafts ( n = 2), bare-metal stents ( n = 1), or the off-label use of iliac limb stent grafts ( n = 5). Renal embolization was found in 3 (17.6%) patients during intraoperative angiography. There was 1 (5.9%) case of distal runoff embolization after CDT and 1 (5.9%) case of left iliac artery rupture. One (5.9%) death occurred due to acute myocardial infarction 20 days after the operation. The average follow-up period was 19.3 ± 16.7 months (range, 1–54 months) in the remaining 16 cases. The renal artery patency rate was 100%. The estimated cumulative primary patency rates were 92.3% at 12 months and 59.3% at 36 months according to the Kaplan–Meier method. Conclusions Transbrachial and transfemoral approaches combined with visceral protection offer a safe and effective alternative to open revascularization for the endovascular treatment of juxtarenal AIOD.

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Iliocaval Reconstruction of Chronically Thrombosed Cylindrical Inferior Vena Cava Filters with Balloon Expandable Covered Stent Grafts.

Journal of Vascular Surgery Cases and Innovative Techniques ◽

10.1016/j.jvscit.2021.05.006 ◽

2021 ◽

Author(s):

Mohamed Elboraey ◽

Beau B. Toskich ◽

Andrew R. Lewis ◽

Charles A. Ritchie ◽

Gregory T. Frey ◽

...

Keyword(s):

Inferior Vena Cava ◽

Inferior Vena ◽

Vena Cava ◽

Covered Stent ◽

Stent Grafts ◽

Inferior Vena Cava Filters ◽

Vena Cava Filters

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A tissue engineering construct comprising human endometrial mesenchymal stromal cells and polyamide/gelatin mesh evaluated in a preclinical animal model of pelvic organ prolapse repair

Cytotherapy ◽

10.1016/j.jcyt.2013.01.016 ◽

2013 ◽

Vol 15 (4) ◽

pp. S5

Author(s):

D. Ulrich ◽

S.L. Edwards ◽

J.F. White ◽

C. Su ◽

K. Tan ◽

...

Keyword(s):

Tissue Engineering ◽

Animal Model ◽

Pelvic Organ Prolapse ◽

Mesenchymal Stromal Cells ◽

Stromal Cells ◽

Pelvic Organ ◽

Prolapse Repair ◽

Preclinical Animal Model ◽

Tissue Engineering Construct ◽

Pelvic Organ Prolapse Repair

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Cost-Effectiveness Evaluation of Tips Procedures with Expanded Polytetrafluoroethylene (EPTFE) Covered Stent-Grafts Compared to Large Volume Paracentesis in Patients with Refractory Ascites – A Spanish Scenario

Value in Health ◽

10.1016/j.jval.2016.09.1988 ◽

2016 ◽

Vol 19 (7) ◽

pp. A693

Author(s):

A Pérez-Mitru ◽

A Villacampa Lordan ◽

F Scarpa

Keyword(s):

Cost Effectiveness ◽

Large Volume ◽

Covered Stent ◽

Refractory Ascites ◽

Effectiveness Evaluation ◽

Stent Grafts ◽

Expanded Polytetrafluoroethylene ◽

Large Volume Paracentesis

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Use of Bare Dissection Stents With Covered Stent Grafts Promotes Greater False Lumen Thrombosis and Aortic Remodeling Compared With Covered Stents Alone in All TBAD

Journal of Vascular Surgery ◽

10.1016/j.jvs.2021.06.334 ◽

2021 ◽

Vol 74 (3) ◽

pp. e225

Author(s):

Michael J. Wilderman ◽

David O'Connor ◽

Anjali Ratnathicam ◽

Kristen Cook ◽

Massimo Napolitano ◽

...

Keyword(s):

False Lumen ◽

Covered Stent ◽

Covered Stents ◽

Stent Grafts ◽

Aortic Remodeling

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Abstract 1122‐000097: Recurrent Carotid Cavernous Fistula Requiring Complex Repair of Ruptured Cavernous Carotid Aneurysm: A Case Report

Stroke: Vascular and Interventional Neurology ◽

10.1161/svin.01.suppl_1.000097 ◽

2021 ◽

Vol 1 (S1) ◽

Author(s):

Rami Z. Morsi ◽

Faten El Ammar ◽

Sonam Thind ◽

Scott J. Mendelson ◽

Cedric McKoy ◽

...

Keyword(s):

Visual Acuity ◽

Case Report ◽

Large Scale ◽

Mechanical Valve ◽

Covered Stent ◽

Stent Grafts ◽

Cerebral Angiogram ◽

Safety And Efficacy ◽

Third Nerve Palsy ◽

History Of

Introduction : There are no studies investigating the safety and efficacy of covered stent grafts, particularly the newly developed stents such as the PK Papyrus stent, for endovascular treatment of direct carotid cavernous fistulas (CCFs). Methods : We present a case of a 75‐year‐old female who presented to the hospital with a three‐week history of worsening left eye vision, chemosis, proptosis, and partial third nerve palsy. Patient was found to have left direct Type A CCF secondary to ruptured cavernous segment carotid aneurysm. Results : The CCF was treated with coil embolization and pipeline Shield stent embolization devices with immediate stagnation and improvement of symptoms. Patient had history of an aortic mechanical valve and thus was started on warfarin and ASA. After achieving INR level of 2.5‐3.5, patient started to have recurrent swelling of the left eye associated and decreased visual acuity. Repeated diagnostic cerebral angiogram revealed residual CCF. Onyx liquid embolization and a Surpass Evolve Flow Diverter were attempted to slow the fistulization with no success. Multiple attempts for direct percutaneous superior ophthalmic vein cannulation were also unsuccessful. At this point, two coronary graft‐covered PK Papyrus stents were implanted across the fistula pouch, which resulted in immediate resolution of the CCF with evidence of persistent normal flow within left ophthalmic artery. Patient’s visual acuity and left eye movement improved. Conclusions : This case report highlights the effectiveness and safety of covered stent grafts, particularly more flexible stents such as the PK Papyrus stent, in navigating the carotid vasculature and closing direct CCFs and may be used as a first‐line technique. More large‐scale studies are warranted to investigate the safety and efficacy of using such stent grafts to treat direct CCFs in the setting of antithrombotic agents and anticoagulation.

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