scholarly journals Thoracic composite hemangioendothelioma with neuroendocrine marker expression

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ei Miyamoto ◽  
Kenji Seki ◽  
Hiroyuki Katsuragawa ◽  
Yuji Yoshimoto ◽  
Yuki Ohsumi ◽  
...  

Abstract Background Composite hemangioendothelioma is an extraordinarily rare form of vascular neoplasm which develops predominantly in the skins and soft tissues of the adults. Neuroendocrine marker expression in composite hemangioendothelioma is considered as specifically relevant to the more aggressive behavior. Case presentation The patient was a 71-year-old man complaining continuous back pain. Computed tomography (CT) showed that 10 cm of contrast-enhanced soft tissue mass was occurring on the right posterior chest wall and developing adjacent to the spinal canal. Via the laminectomy, the tumor end was identified and separated from the dura mater. Then, via the posterolateral thoracotomy, the en bloc resection was achieved by separating the tumor from the diaphragm and vertebras. Histologic examination showed a complex combination of epithelioid and retiform hemangioendothelioma areas which were positive for anti-synaptophysin staining. At 12-month follow-up, there were no signs of tumor recurrence on CT, and the patient had no symptom. Conclusions We achieved the complete resection of a huge thoracic neuroendocrine composite hemangioendothelioma developing adjacent to the spinal canal. The combination of the posterior lumbar laminectomy and the following posterior thoracotomy is a viable approach to radically resect a thoracic neuroendocrine composite hemangioendothelioma involving chest wall.

1999 ◽  
Vol 24 (4) ◽  
pp. 501-505 ◽  
Author(s):  
M. van DIJK ◽  
H. A. H. WINTERS ◽  
P. I. J. M. WUISMAN

An osteoblastoma in a carpal bone is very rare and presents a problem of reconstruction after wide tumour excision. We report a case of recurrent osteoblastoma of the right hamate bone with involvement of the ulnar carpal bones and soft tissues that was successfully treated by en bloc resection, temporary interposition of bone cement and fixation with K-wires, followed by reconstruction with a free vascularized iliac crest flap, tailored to the exact size of the defect, in a second procedure. Rapid fusion was achieved and hand function preserved with no evidence of recurrence 3 years postoperatively.


Author(s):  
Houssem Harbi ◽  
Amira Akrout ◽  
Mohamed Fourati ◽  
Amine Zouari ◽  
Nozha Toumi

A 68-year-old female was operated for a giant dedifferentiated retroperitoneal liposarcoma (RLS) encasing entirely the right kidney. She had an en-bloc resection of the tumor with right nephrectomy. The en-bloc resection should avoid R1 resection margins. Renal conservation is suggested if the kidney is widely displaced and for elderly patient.


2001 ◽  
Vol 121 (4) ◽  
pp. 649-656 ◽  
Author(s):  
Francesco Facciolo ◽  
Giuseppe Cardillo ◽  
Michele Lopergolo ◽  
Guido Pallone ◽  
Francesco Sera ◽  
...  

2018 ◽  
Vol 67 (04) ◽  
pp. 299-305 ◽  
Author(s):  
Marco Chiappetta ◽  
Dania Nachira ◽  
Maria Teresa Congedo ◽  
Elisa Meacci ◽  
Venanzio Porziella ◽  
...  

Background The aim of this study was to identify prognostic factors in patients affected by non-small cell lung cancer (NSCLC) with chest wall (CW) involvement, analyzing different strategies of treatment and surgical approaches. Methods Records of 59 patients affected by NSCLC with CW involvement underwent surgery were retrospectively reviewed, from January 2000 to March 2013. Results Induction therapy was administered to 18 (30.5%) patients while adjuvant treatment to 36 (61.0%). In 36 (61%) patients, lung resection was associated only with a parietal pleural resection while in 23 (39%) with CW en-bloc resection. Overall 5-year survival was 34%. Prognostic factors were evaluated in the 51 (86.4%) completely resected (R0) patients.Five-year survival was 60% in patients undergoing induction therapy followed by surgery and 24% in those who underwent surgery as first treatment (p = 0.11). Five-year survival was better in the neoadjuvant group than that in the surgery group in IIB (T3N0) p-stage (100 vs 28%, p = 0.03), while in the IIIA (T3N1–2,T4N0) p-stage it was of 25 vs 0%, respectively (p = 0.53).No 5-year survival difference was found in case of parietal pleural resection versus CW en-bloc resection (p = 0.27) and in case of only parietal pleural involvement versus soft tissue (p = 0.78).In case of incomplete resection (R1), patients undergoing adjuvant radiotherapy had better 2-year survival than patients untreated: 60% vs 0% (p = 0.025). Conclusions Type of surgical resection and the deep of infiltration of disease do not influence survival in this subset of patients. Integrated treatments seem to be suitable: neoadjuvant therapies ensure a better survival rate than surgery alone in IIB and IIIA patients, instead adjuvant radiotherapy proves a fundamental option in incomplete resections.


1983 ◽  
Vol 92 (5) ◽  
pp. 532-533 ◽  
Author(s):  
John G. Batsakis ◽  
Kenneth D. McClatchey

Ameloblastomas arising in the supraperiosteal soft tissues (peripheral ameloblastoma) and those taking origin in the maxilla have distinctively different biologic behaviors. The peripheral ameloblastoma can be successfully treated by conservative excision while en bloc resection is warranted for the maxillary ameloblastoma. The effectiveness of primary surgical treatment of an ameloblastoma of the maxilla is the key to reduce morbidity and mortality from the lesion. Anatomic differences between the maxilla and mandible and an apparent more aggressive behavior of maxillary tumors also play a role in establishing the ameloblastoma of the maxilla as the most dangerous of the ameloblastomas.


2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Heron Teixeira Andrade Santos ◽  
Agnaldo José Lopes ◽  
Cláudio Higa ◽  
Rodolfo Acatauassú Nunes ◽  
Eduardo Haruo Saito

2018 ◽  
Vol 106 (1) ◽  
pp. 207-213 ◽  
Author(s):  
Bastien Provost ◽  
Gilles Missenard ◽  
Ciprian Pricopi ◽  
Olaf Mercier ◽  
Sacha Mussot ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
pp. 141
Author(s):  
Haruka Fujinami ◽  
Akira Teramoto ◽  
Saeko Takahashi ◽  
Takayuki Ando ◽  
Shinya Kajiura ◽  
...  

This study aimed to assess the utility of the S-O clip during colorectal endoscopic submucosal dissection (ESD). We conducted a retrospective study on 185 patients who underwent colorectal ESD from January 2015 to January 2020. The patients were divided into two groups: before and after the introduction of the S-O clip. Forty-two patients underwent conventional ESD (CO group) and 29 patients underwent ESD using the S-O clip (SO group). We compared the surgery duration, dissection speed, en bloc resection rate, and complication rate between both groups. Compared with the CO group, the SO group had a significantly shorter surgery duration (70.7 ± 37.9 min vs. 51.2 ± 18.6 min; p = 0.017), a significantly higher dissection speed (15.1 ± 9.0 min vs. 26.3 ± 13.8 min; p < 0.001), a significantly higher en bloc resection rate (80.9% vs. 98.8%; p ≤ 0.001), and a significantly lower perforation rate (4.3% vs. 1.3%). In the right colon, the surgery duration was significantly shorter and the dissection speed was significantly higher in the SO group than in the CO group. Moreover, the rate of en bloc resection improved significantly in the right colon. S-O clip-assisted ESD reduces the procedure time and improves the treatment effects, especially in the right colon.


2019 ◽  
Vol 26 (09) ◽  
pp. 1597-1599
Author(s):  
Mukesh Kumar ◽  
Masroor Ahmed ◽  
Muhammad Saleem ◽  
Khurram Sahar

Osteoclastoma (Giant Cell Tumor) of Cuboid bone is a rare bone tumor. GCT is primarily seen in metaphyseo-epiphyseal region of long bones after skeletal maturity. This patient is a 17 years old female, presented with painful swelling of the right foot. On conventional radiographs, there is osteolytic lesion in Cuboid bone of right foot. En bloc resection and autologous bone grafting (iliac crest) was done. Patient's pain and swelling disappeared following the procedure and there is no evidence of recurrence at 18 months follow up.


Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 918
Author(s):  
Maike Rohländer ◽  
Henning Otzen ◽  
Kristina Rode ◽  
Klaus Jung ◽  
Marion Schmicke ◽  
...  

The aim of this study was to test whether a single testicular needle biopsy could provide histological results comparable to en bloc resection histology and whether one biopsy was sufficient to reflect the histology of an entire pair of testicles. Two methods of sample collection were tested on 32 bull calves aged five to eight months to compare histological parameters of needle biopsy with those of en bloc resection samples. One testicular needle biopsy of the right and three en bloc samples of both testicles were collected and compared for the number of tubular cross sections, tubules with elongated spermatids (ES), outer/inner diameter of tubules, thickness of tubular wall, and number of Sertoli cells (SC). Additionally, animal data were considered. No significant differences were found between the left and right testis or among the individual locations of en bloc samples. However, histologically significant differences (Bonferroni-adjusted significance level: p < 0.05/6 = 0.0083) were found between the needle biopsy and en bloc resection regarding the tubular cross sections per visual field (p < 0.05), the outer (p = 0.01) and inner diameter and the thickness of the tubular wall (both p < 0.01). In the SOX9 immunohistochemical staining, no significant differences (p > 0.05) could be observed for SC numbers between needle biopsy and en bloc samples. In conclusion, results of testicular needle biopsy do not have the same validity as the en bloc resection histology. Furthermore, one biopsy is insufficient to reflect the histology of the entire testicular pair.


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