scholarly journals Protective effects of tea polyphenols and β-carotene against γ-radiation induced mutation and oxidative stress in Drosophila melanogaster

2017 ◽  
Vol 39 (1) ◽  
Author(s):  
Isha Nagpal ◽  
Suresh K. Abraham
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Tea Polyphenols ◽  
Protective Effects ◽  
Γ Radiation ◽  
Induced Mutation ◽  
Radiation Induced ◽  
And Oxidative Stress ◽  
Β Carotene

Amelioration of γ-radiation induced genomic insult and oxidative stress in whole body irradiated Swiss albino mice by sesamol

2011 ◽  
Vol 8 (1) ◽  
pp. 20 ◽  
Author(s):  
Gopakumar Gopinathan Nair ◽  
Cherupally Krishnan Krishnan Nair
Keyword(s):  
Oxidative Stress ◽  
Whole Body ◽  
Γ Radiation ◽  
Swiss Albino Mice ◽  
Radiation Induced ◽  
Albino Mice ◽  
And Oxidative Stress

Protective effects of chlorogenic acid, curcumin and β-carotene against γ-radiation-induced in vivo chromosomal damage

1993 ◽  
Vol 303 (3) ◽  
pp. 109-112 ◽  
Author(s):  
Suresh K. Abraham ◽  
Lakshmi Sarma ◽  
P.C. Kesavan
Keyword(s):  
Chlorogenic Acid ◽  
Protective Effects ◽  
Chromosomal Damage ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Β Carotene

Intake of saffron reduces γ-radiation-induced genotoxicity and oxidative stress in mice

2017 ◽  
Vol 27 (6) ◽  
pp. 428-434 ◽  
Author(s):  
Apurva Koul ◽  
Suresh K. Abraham
Keyword(s):  
Oxidative Stress ◽  
Γ Radiation ◽  
Radiation Induced ◽  
And Oxidative Stress

Buthionine sulfoximine mediated enhancement of γ-radiation induced mutation frequency in Drosophila melanogaster

1993 ◽  
Vol 301 (4) ◽  
pp. 255-259 ◽  
Author(s):  
Suresh K. Abraham ◽  
S.P. Singh ◽  
P.C. Kesavan
Keyword(s):  
Drosophila Melanogaster ◽  
Mutation Frequency ◽  
Buthionine Sulfoximine ◽  
Γ Radiation ◽  
Induced Mutation ◽  
Radiation Induced

Effects of Montmorillonite on Growth Performance, Serum Biochemistry and Oxidative Stress of Red-Crowned Crane (Grus japonensis) Fed Mycotoxin-Contaminated Feed

2020 ◽  
Vol 21 (8) ◽  
pp. 626-632 ◽  
Author(s):  
Dawei Liu ◽  
Qinghua Wu ◽  
Hongyi Liu ◽  
Changhu Lu ◽  
Chao Gu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Growth Performance ◽  
Feed Intake ◽  
Animal Feed ◽  
Bird Species ◽  
Serum Biochemistry ◽  
Protective Effects ◽  
Regular Diet ◽  
Grus Japonensis ◽  
And Oxidative Stress

Background: The red-crowned crane (Grus japonensis) is one of the most vulnerable bird species in the world. Mycotoxins are toxic secondary metabolites produced by fungi and considered naturally unavoidable contaminants in animal feed. Our recent survey indicated that the mycotoxins had the potential to contaminate redcrowned crane’s regular diets in China. Objective: This experiment was conducted to investigate the protective effects of mycotoxin binder montmorillonite (Mont) on growth performance, serum biochemistry and oxidative stress parameters of the red-crowned crane. Methods: 16 red-crowned cranes were divided into four groups and fed one of the following diets; a selected diet, regular diet, or the selected diet or regular diet with 0.5% montmorillonite added to the diets. The cranes' parameters of performance, hematology, serum biochemistry and serum oxidative stress were measured. Results: Consuming regular diets decreased the average daily feed intake (ADFI), levels of haemoglobin (Hb), platelet count (PLT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT), but increased the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK) and lactate dehydrogenase (LDH). The supplementation of 0.5% Mont provided protection for the red-crowned crane in terms of feed intake, serum biochemistry and oxidative stress. Moreover, Mont supplementation had no adverse effect on the health of red-crowned crane. Conclusions: Taken together, these findings suggested that the addition of dietary Mont is effective in improving the health of red-crowned crane.

Hyperbaric oxygen treatment reverses radiation induced pro-fibrotic and oxidative stress responses in a rat model

2017 ◽  
Vol 103 ◽  
pp. 248-255 ◽  
Author(s):  
N. Oscarsson ◽  
L. Ny ◽  
J. Mölne ◽  
F. Lind ◽  
S.-E. Ricksten ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Hyperbaric Oxygen ◽  
Rat Model ◽  
Stress Responses ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment ◽  
Radiation Induced ◽  
Oxidative Stress Responses ◽  
And Oxidative Stress

The protective effects of carvacrol and thymol against paracetamol–induced toxicity on human hepatocellular carcinoma cell lines (HepG2)

2016 ◽  
Vol 35 (12) ◽  
pp. 1252-1263 ◽  
Author(s):  
SS Palabiyik ◽  
E Karakus ◽  
Z Halici ◽  
E Cadirci ◽  
Y Bayir ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Cytokines ◽  
Hepg2 Cells ◽  
Folk Medicine ◽  
Hepatoprotective Activity ◽  
High Dose ◽  
Protective Effects ◽  
And Oxidative Stress ◽  
Pro Inflammatory Cytokines

Acetaminophen (APAP) overdose could induce liver damage and lead to acute liver failure. The treatment of APAP overdoses could be improved by new therapeutic strategies. Thymus spp., which has many beneficial effects and has been used in folk medicine, is one such potential strategy. In the present study, the hepatoprotective activity of the main constituents of Thymus spp., carvacrol and thymol, were evaluated in light of APAP-induced hepatotoxicity. We hoped to understand the hepatoprotective mechanism of these agents on the antioxidant system and pro-inflammatory cytokines in vitro. Dose-dependent effects of thymol and carvacrol (25, 50, and 100 µM) were tested on cultured HepG2 cells. N-Acetylcysteine (NAC) was tested as positive control. We showed that APAP inhibited HepG2 cell growth by inducing inflammation and oxidative stress. Incubating APAP-exposed HepG2 cells with carvacrol and thymol for 24 h ameliorated this inflammation and oxidative stress. We also evaluated alanine transaminase and lactate dehydrogenase levels of HepG2 cells. We found that thymol and carvacrol protected against APAP-induced toxicity in HepG2 cells by increasing antioxidant activity and reducing pro-inflammatory cytokines, such as tumor necrosis factor α and interleukin 1β. Taking together high-dose thymol and carvacrol treatment has an effect close to NAC treatment in APAP toxicity, but thymol has better treatment effect than carvacrol.

The protective effects of Δ9 -tetrahydrocannabinol against inflammation and oxidative stress in rat liver with fructose-induced hyperinsulinemia

2018 ◽  
Vol 71 (3) ◽  
pp. 408-416 ◽  
Author(s):  
Alisa Bahar Beydogan ◽  
Zeynep Mine Coskun ◽  
Sema Bolkent
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Protective Effects ◽  
And Oxidative Stress
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