scholarly journals A case of Sphingomonas paucimobilis causing peritoneal dialysis-associated peritonitis and review of the literature

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Chiharu Kinoshita ◽  
Koichi Matsuda ◽  
Yumiko Kawai ◽  
Takayuki Hagiwara ◽  
Akane Okada

Abstract Background Peritoneal dialysis (PD)-associated peritonitis caused by Sphingomonas paucimobilis (S. paucimobilis) is very rare, and most of the characteristics of such cases are still unknown. Case presentation An 80-year-old Japanese woman on PD was diagnosed with PD-associated peritonitis and received ceftazidime and cefazolin. The number of cells in the peritoneal dialysate decreased quickly. However, because S. paucimobilis was detected, the antibiotic was changed to meropenem according to the susceptibility test results. She was treated with meropenem for two weeks and discharged. After 21 days, she was hospitalized for relapsing peritonitis. S. paucimobilis was detected again, and improvement after the administration of meropenem was poor, eventually resulting in catheter removal. Conclusions S. paucimobilis may be resistant to empirical antibiotics; furthermore, catheter removal may still be required, even with sensitive-antibiotic treatment.

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Hideya Itagaki ◽  
Suzuki Katuhiko

Abstract Background Edoxaban is an orally administered anticoagulant treatment that is used in patients with cerebral infarction, venous thrombosis, or other conditions, with a reported incidence of gastrointestinal hemorrhage at approximately 1%. We encountered the rare case of a patient who developed a gallbladder hemorrhage after the administration of edoxaban. Case presentation An 86-year-old Japanese woman visited our gastrointestinal department due to the chief complaint of melena lasting for a week. Her medical history included hypertension and embolic cerebral infarction, and she was taking orally administered carvedilol (5 mg/day) and edoxaban (30 mg/day). Her palpebral conjunctiva was pale during a physical examination, indicating the possibility of anemia. Her blood test results confirmed severe anemia with red blood cells at 1.7 × 106/μL and hemoglobin at 4.7 g/dL. An upper gastrointestinal endoscopy revealed bile and fresh blood on the duodenal bulb and in more distal regions; hemobilia was suspected. A computed tomography scan on the ninth hospitalization day confirmed the hemobilia with a gallbladder fundus high-density signal. She was discharged on the 30th day of hospitalization with only fluid therapy and no progression of anemia. Moreover, she underwent a laparoscopic cholecystectomy 1 month after discharge, but the pathologist did not identify false aneurysms or neoplastic lesions. She has not been shown to develop anemia for 5 months after surgery. Conclusions Our case suggests that gallbladder hemorrhage needs to be considered a possible complication for patients on direct oral anticoagulants.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Ryota Matsuoka ◽  
Noriaki Sakamoto ◽  
Takayasu Kato ◽  
Shigeru Chiba ◽  
Masayuki Noguchi

Abstract Background Solitary plasmacytoma of bone (SPB) is a rare plasma cell neoplasm. It arises in bone as a single locus in the absence of any plasma cell myeloma lesions. Plasma cell neoplasms intrinsically express only one immunoglobulin light chain (IgL)—kappa or lambda—and using this fact, kappa/lambda deviation is the decisive factor for diagnosis. Co-expression of both IgLs in a single tumor cell is extremely rare. Case presentation We report a case of SPB that arose in the vertebra of a 52-year-old Japanese woman. Histologically, the resected mass showed diffuse plasma cell proliferation. Dual IgL expression was detected by flow cytometry, immunohistochemistry, and in situ hybridization (ISH) targeting IgL mRNA. Conclusion We have presented an extremely rare case of SPB showing dual expression of kappa and lambda IgLs. This unusual case of plasma cell neoplasia might represent a possible exceptional example of failure of “IgL isotypic exclusion.”


2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Daisuke Katsura ◽  
Suzuko Moritani ◽  
Shunichiro Tsuji ◽  
Kounosuke Suzuki ◽  
Kazutaka Yamada ◽  
...  

Abstract Background Uterine inversion may cause massive hemorrhage, resulting in maternal deterioration and death. Replacement of the inverted uterus must be performed as soon as possible. As time passes, the inverted uterus becomes atonic and necrotic, and a surgical approach may be required. Case presentation A 27-year-old Japanese woman was admitted to our hospital 4 hours postpartum with increased hemorrhage after the replacement of an inverted uterus. Recurrent inversion was diagnosed, and though the atonic uterus was replaced again by the Johnson maneuver, hemorrhage persisted. Balloon tamponade was not successful in stopping the hemorrhage, and uterine artery embolization was performed. Bleeding resumed the next day on removal of the balloon, and hysterectomy was performed. Massive hemorrhage, coagulopathy, and uterine necrosis caused uterine atony, and the reperfused blood flow on replacement of the ischemic uterus increased hemorrhage. Conclusions Cases of uterine inversion with coagulopathy lasting for more than 4 hours may require a surgical intervention, and uterine replacement may have to be delayed until the maternal hemodynamic condition is stabilized. Uterine replacement under laparotomy may be also be considered due to the risk of increased hemorrhage.


1996 ◽  
Vol 16 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Joseph T. Flynn ◽  
Debrah Meislich ◽  
Bruce A. Kaiser ◽  
Martin S. Polinsky ◽  
H. Jorge Baluarte

Objective To review various aspects of the management of peritonitis due to Fusarium, a soil mold which infrequently causes infections in humans. Data Sources A case of Fusarium peritonitis in a child on chronic peritoneal dialysis (PD) is presented. The child developed Fusarium peritonitis 2 weeks after an episode of bacterial peritonitis. His Tenckhoff catheter was removed, and he was maintained on hemodialysis while receiving intravenous amphotericin. Following 2 weeks of treatment with amphotericin, he was successfully returned to PD. A literature review of all previously reported cases of Fusarium peritonitis was then conducted to determine features common to infections caused by Fusarium. Emphasis was also placed on unique characteristics of the organism that may affect patient management, as well as patient characteristics that may increase the risk for infection by Fusarium. Results Fusarium may cause infection inimmuno suppressed individuals, such as cancer patients or patients on chronic PD. The organism has a propensity to attach to foreign bodies such as intravascular and intraperitoneal catheters. Therefore, successful treatment of infections caused by Fusarium may require catheter removal in addition to systemic antifungal therapy. Conclusions This report presents the first known case of Fusarium peritonitis in a child. In view of the difficulties posed by this unusual organism, optimal therapy of Fusarium peritonitis should consist of immediate catheter removal and treatment with systemic antifungal drugs.


1985 ◽  
Vol 5 (1) ◽  
pp. 65-67 ◽  
Author(s):  
Satoshi Kurihara ◽  
Yoshio Tani ◽  
Keita Tateishi ◽  
Takehisa Yuri ◽  
Hirohisa Kitada ◽  
...  

A 42-year-old Japanese woman developed an eczematous skin rash around the catheter exit during continuous ambulatory peritoneal dialysis (CAPD). The same kind of lesion developed around a Scribner shunt exit. Skin biopsy indicated chronic eosinophilic dermatitis. In the patch test she developed an allergic reaction to the silicone rubber catheter but not to the antiseptic solutions. Based on these findings, we concluded that her “eczematous” rash represented an allergic response to silicone rubber in the peritoneal catheter. To this date the literature contains no reports of such a catheter complication in CAPD. Catheter complications in patients on CAPD are mainly infection and mechanical dysfunction such as poor drainage or leaks (I, 2). Eosinophilic dermatitis around the catheter exit caused by the silicone rubber is extremely uncommon (3). As yet no reports have been published concerning this rare catheter complication.


2016 ◽  
Vol 36 (6) ◽  
pp. 680-684 ◽  
Author(s):  
Troy A. Markel ◽  
Karen W. West

Erosion of peritoneal dialysis (PD) catheters into the intestine is a rare complication of PD. Herein, we convey the first reports of 2 pediatric patients undergoing PD who were found to have the catheter eroding into their intestines. They were treated minimally with catheter removal and antibiotics. Definitive repair of the intestinal injury was not performed. These are the first pediatric patients reported with PD catheter erosion. Perforating injuries may be self-limiting, and therefore a more minimal approach may be considered in certain patient populations who do not express overt signs of peritonitis or illness.


2021 ◽  
Author(s):  
Ryota Matsuoka ◽  
Noriaki Sakamoto ◽  
Takayasu Kato ◽  
Shigeru Chiba ◽  
Masayuki Noguchi

Abstract Background: Solitary plasmacytoma of bone (SPB) is a rare plasma cell neoplasm. It arises in bone as a single locus in the absence of any plasma cell myeloma lesions. Plasma cell neoplasms intrinsically express only one immunoglobulin light chain (IgL) – kappa or lambda – and using this fact, kappa/lambda deviation is the decisive factor for diagnosis. Coexpression of both IgLs in a single tumor cell is extremely rare.Case presentation: We report a case of SPB that arose in the vertebra of a 52-year-old Japanese woman. Histologically, the resected mass showed diffuse plasma cell proliferation. Dual IgL expression was detected by flow cytometry, immunohistochemistry and in situ hybridization (ISH) targeting IgL mRNA.Conclusion: We have presented an extremely rare case of SPB showing dual expression of kappa and lambda IgLs. This unusual case of plasma cell neoplasia might represent a possible exceptional example of failure of “IgL isotypic exclusion”.


2016 ◽  
Vol 5 (2) ◽  
pp. 197-202 ◽  
Author(s):  
Jun Yamazaki ◽  
Eriko Kanehisa ◽  
Wakaba Yamaguchi ◽  
Jiro Kumagai ◽  
Kiyotaka Nagahama ◽  
...  

2008 ◽  
Vol 123 (7) ◽  
pp. 793-795 ◽  
Author(s):  
T Kanazawa ◽  
R Inoue ◽  
Y Ohta ◽  
Y Watanabe ◽  
Y Iino

AbstractObjective:We report an extremely rare case of maxillary haemangioma.Method:Case report and review of the literature concerning haemangioma arising from the nasal cavity and paranasal sinuses.Results:Maxillary haemangioma is rare and sometimes requires wider resection than nasal haemangioma if a large tumour is found. We present a case of maxillary haemangioma in a 37-year-old Japanese woman, which was completely resected by pre-operative embolisation and endoscopic sinus surgery.Conclusion:Our findings suggest that if a large maxillary haemangioma is diagnosed pre-operatively, the treatment of choice is pre-operative embolisation followed by endoscopic sinus surgery, in order to avoid the surgical complications associated with wide resection.


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