scholarly journals Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndrome

2012 ◽  
Vol 3 (2) ◽  
pp. 14 ◽  
Author(s):  
Xiaoning Mou ◽  
Yuanbo Wu ◽  
Henghua Cao ◽  
Qingzhang Meng ◽  
Qihui Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Down Syndrome ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Induced Pluripotent ◽  
Disease Specific

Neurons Derived from Induced Pluripotent Stem Cells of Patients with Down Syndrome Reproduce Early Stages of Alzheimer’s Disease Type Pathology in vitro

2017 ◽  
Vol 56 (2) ◽  
pp. 835-847 ◽  
Author(s):  
Erdem B. Dashinimaev ◽  
Alexander S. Artyuhov ◽  
Alexey P. Bolshakov ◽  
Ekaterina A. Vorotelyak ◽  
Andrey V. Vasiliev
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cells ◽  
Down Syndrome ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Disease Type ◽  
Early Stages ◽  
Induced Pluripotent

scholarly journals The Promise of Human Induced Pluripotent Stem Cells in Dental Research

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Thekkeparambil Chandrabose Srijaya ◽  
Padmaja Jayaprasad Pradeep ◽  
Rosnah Binti Zain ◽  
Sabri Musa ◽  
Noor Hayaty Abu Kasim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Disease Modeling ◽  
Patient Specific ◽  
Dental Research ◽  
Cell Based Therapy ◽  
Induced Pluripotent ◽  
Disease Specific

Induced pluripotent stem cell-based therapy for treating genetic disorders has become an interesting field of research in recent years. However, there is a paucity of information regarding the applicability of induced pluripotent stem cells in dental research. Recent advances in the use of induced pluripotent stem cells have the potential for developing disease-specific iPSC linesin vitrofrom patients. Indeed, this has provided a perfect cell source for disease modeling and a better understanding of genetic aberrations, pathogenicity, and drug screening. In this paper, we will summarize the recent progress of the disease-specific iPSC development for various human diseases and try to evaluate the possibility of application of iPS technology in dentistry, including its capacity for reprogramming some genetic orodental diseases. In addition to the easy availability and suitability of dental stem cells, the approach of generating patient-specific pluripotent stem cells will undoubtedly benefit patients suffering from orodental disorders.

Neurodegenerative disease-specific induced pluripotent Stem cells research

2009 ◽  
Vol 65 ◽  
pp. S10
Author(s):  
Haruhisa Inoue ◽  
Shiho Kitaoka ◽  
Motoko Naitoh ◽  
Kazutoshi Takahashi ◽  
Katsuhiro Yoshikawa ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neurodegenerative Disease ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Induced Pluripotent ◽  
Disease Specific

scholarly journals Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

2012 ◽  
Vol 11 (5) ◽  
pp. 615-619 ◽  
Author(s):  
Li B. Li ◽  
Kai-Hsin Chang ◽  
Pei-Rong Wang ◽  
Roli K. Hirata ◽  
Thalia Papayannopoulou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Down Syndrome ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Induced Pluripotent

scholarly journals Generation of Integration-Free Induced Pluripotent Stem Cells from Urine-Derived Cells Isolated from Individuals with Down Syndrome

2017 ◽  
Vol 6 (6) ◽  
pp. 1465-1476 ◽  
Author(s):  
Young M. Lee ◽  
Bruna L. Zampieri ◽  
Jonah J. Scott-McKean ◽  
Mark W. Johnson ◽  
Alberto C.S. Costa
Keyword(s):  
Stem Cells ◽  
Down Syndrome ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Induced Pluripotent

scholarly journals Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery

2012 ◽  
Vol 44 (3) ◽  
pp. 202 ◽  
Author(s):  
Jiho Jang ◽  
Jeong-Eun Yoo ◽  
Jeong-Ah Lee ◽  
Dongjin R. Lee ◽  
Ji Young Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Drug Discovery ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Human Disease ◽  
Disease Modeling ◽  
Induced Pluripotent ◽  
Disease Specific
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