Bayesian spatio-temporal analysis of joint patterns of male and female lung cancer risks in Yorkshire (UK)

2006 ◽  
Vol 15 (4) ◽  
pp. 385-407 ◽  
Author(s):  
Sylvia Richardson ◽  
Juan J Abellan ◽  
Nicky Best
2017 ◽  
Vol 27 (3) ◽  
pp. S49-S57 ◽  
Author(s):  
Koshi Nakamura ◽  
Shigekazu Ukawa ◽  
Emiko Okada ◽  
Makoto Hirata ◽  
Akiko Nagai ◽  
...  

2015 ◽  
Vol 39 (3) ◽  
pp. 430-439 ◽  
Author(s):  
Susanna M. Cramb ◽  
Peter D. Baade ◽  
Nicole M. White ◽  
Louise M. Ryan ◽  
Kerrie L. Mengersen

Author(s):  
Angeline S. Andrew ◽  
Meifang Li ◽  
Xun Shi ◽  
Judy R. Rees ◽  
Karen M. Craver ◽  
...  

Trichloroethylene (TCE) is a well-documented kidney carcinogen based on a substantial body of evidence including mechanistic and animal studies, as well as reports from occupational settings. However, the cancer risks for those in residential exposures such as TCE contamination in groundwater are much less clear. The objective of this study was to perform a detailed spatio-temporal analysis of estimated residential TCE exposure in New Hampshire, US. We identified kidney cancer cases (n = 292) and age-, gender-matched controls (n = 448) from the Dartmouth-Hitchcock Health System and queried a commercial financial database for address histories. We used publically available data on TCE levels in groundwater measured at contaminated sites in New Hampshire and then modeled the spatial dispersion and temporal decay. We overlaid geospatial residential locations of cases and controls with yearly maps of estimated TCE levels to estimate median exposures over the 5, 10, and 15-year epochs before diagnosis. The 50th–75th percentile of estimated residential exposure over a 15-year period was associated with increased kidney cancer risk (adjusted Odds Ratio (OR) 1.78 95% CI 1.05–3.03), compared to <50th percentile. This finding supports the need for groundwater monitoring of TCE contaminated sites to identify potential public health risks.


BMC Cancer ◽  
2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Oscar Zurriaga ◽  
Hermelinda Vanaclocha ◽  
Miguel A Martinez-Beneito ◽  
Paloma Botella-Rocamora

2009 ◽  
Vol 129 (10) ◽  
pp. 1778-1784
Author(s):  
Yasuaki Uehara ◽  
Keita Tanaka ◽  
Yoshinori Uchikawa ◽  
Bong-Soo Kim

2010 ◽  
Vol 17 (4) ◽  
pp. 770-775
Author(s):  
Ren YANG ◽  
Zhi-Yuan REN ◽  
Qian XU ◽  
Mei-Xia WANG

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