Electrodermal Activity in Depression: Clinical and Biochemical Correlates

1980 ◽  
Vol 137 (1) ◽  
pp. 93-97 ◽  
Author(s):  
A. M. Mirkin ◽  
A. Coppen

SummaryElectrodermal activity was measured in a group of depressive patients and normal controls. Those patients classified as endogenous on the Newcastle Scale had significantly lower skin conductance levels than either the non-endogenous patients or controls. The endogenous depressives also contained significantly more non-responders to the experimental stimuli. The lack of responsivity to external stimulation in non-responders is associated with a significantly lower rate of blood platelet 5-hydroxytryptamine uptake, suggesting that endogenous depressives have biological characteristics that distinguish them from other depressive groups and that electrodermal measures may be useful in the classification of depressive illness.

1994 ◽  
Vol 79 (1) ◽  
pp. 611-622 ◽  
Author(s):  
Carmen Benjamins ◽  
Albert H. B. Schuurs ◽  
Johan Hoogstraten

The present study assesses the relationship between self-reported dental anxiety (Dental Anxiety Inventory, Dental Anxiety Scale, and Duration of Psychophysiological Fear Reactions), electrodermal activity (skin-conductance level and frequency of spontaneous responses), and Marlowe-Crowne defensiveness. All measurements were made twice. The first session was scheduled immediately before a semi-annual dental check-up (stress condition), and baseline measurements were made two months later without the prospect of a dental appointment. Subjects were male dental patients who regularly attended a university dental clinic and a clinic for Special Dental Care. The main findings were that the low anxious-high defensive-scoring (Marlowe-Crowne Denial subscale) university patients showed significantly higher skin-conductance levels and frequency of nonspecific fluctuations than the low anxious-low defensive-scoring subjects. Besides, the conductance values of the low anxious-high defensive-scoring subjects resembled those of the high anxious-low defensive-scoring patients of the clinic for Special Dental Care, the baseline frequency of nonspecific fluctuations excepted.


1980 ◽  
Vol 137 (3) ◽  
pp. 229-232 ◽  
Author(s):  
P. Linkowski ◽  
H. Brauman ◽  
J. Mendlewicz

SummaryPlasma growth hormone (GH) release after TRH injection was investigated in 27 unipolar and 23 bipolar depressive women, and in 39 normal female controls matched for age, sex and menopausal status. Peaks of GH secretion after TRH were observed in some depressive patients as well as in some normal controls, but there were no significant differences in GH response after TRH administration between patients and controls. The implications of these findings are discussed in reference to such factors as non-specific stress responses and abnormal neuroendocrine circadian rhythms in affectively ill patients.


Biofeedback ◽  
2016 ◽  
Vol 44 (2) ◽  
pp. 90-100 ◽  
Author(s):  
Fredric Shaffer ◽  
Didier Combatalade ◽  
Erik Peper ◽  
Zachary M. Meehan

Valid electrodermal measurements ensure the integrity of client assessment and biofeedback training. Accurate measurements require understanding of the signal and potential artifacts (sources of contamination) and developing “bulletproof procedures.” Peper, Shaffer, and Lin have recommended the following guidelines for ensuring accurate psychophysiological monitoring: (a) understand the physiological mechanisms that generate the signal, (b) always record and inspect the raw signal because this will allow you to identify artifact, (c) question whether displayed values make sense (e.g., skin conductance levels that rapidly fluctuate, exceed 40 μS/cm2, or fall below 1 μS/cm2 should be suspect in a client who is sitting quietly), (d) recognize the appearance of common artifacts and how they alter derived measurements, and (e) intentionally create artifacts so that you can better recognize them (e.g., rhythmically move the fingers attached to a skin sensor, loosening or tightening the sensors if they are attached with the Velcro® finger straps, and review both the raw signal and calculated skin conductance values). This article reviews the anatomy and physiology, measurement procedures, sources of common artifacts and their control, tracking test for recording electrodermal activity, and common response patterns.


2007 ◽  
Author(s):  
Alyssa T. Nguyen ◽  
Senqi Hu ◽  
Gregg Gold ◽  
Brittaini Graham ◽  
Kevin Howerton

1988 ◽  
Vol 78 (6) ◽  
pp. 743-753 ◽  
Author(s):  
L.-H. Thorell ◽  
B. F. Kjellman ◽  
G. d'Elia ◽  
B. Kågedal

1980 ◽  
Vol 10 (2) ◽  
pp. 329-334 ◽  
Author(s):  
B. B. Johnston ◽  
G. J. Naylor ◽  
E. G. Dick ◽  
S. E. Hopwood ◽  
D. A. T. Dick

SYNOPSISA group of bipolar manic depressive patients attending a routine lithium clinic were investigated. The results suggest that, when on treatment with lithium, manic depressive patients with a good prognosis tend to have a higher erythrocyte Na-K ATPase and higher plasma and erythrocyte lithium concentrations than those with a poor prognosis. There was no evidence to suggest that the erythrocyte: plasma lithium ratio was useful in predicting clinical response to lithium therapy. There was also a positive correlation between plasma lithium concentration and Na–K ATPase activity, confirming that in manic depressive subjects lithium produces a rise in erythrocyte Na–K ATPase activity.


2016 ◽  
Vol 26 (4) ◽  
pp. 354-371
Author(s):  
Samantha A. Barry ◽  
Stephanie M. Emhoff ◽  
Ari N. Rabkin ◽  
Christy L. Olezeski ◽  
Melissa Lehrbach ◽  
...  

1986 ◽  
Vol 16 (1) ◽  
pp. 187-197 ◽  
Author(s):  
Joseph E. Herskovic ◽  
Mitchell L. Kietzman ◽  
Samuel Sutton

SynopsisDifferences in response criterion and sensory sensitivity to visual flicker among major depressive patients, dysthymic patients, and normal controls were investigated. Also, signal detection confidence ratings and response times were compared. The results indicated that major depressive patients responded more conservatively (i.e. were less willing to respond ‘flicker’) than either of the other groups. The groups did not differ significantly on a criterion free measure of flicker sensitivity. The major conclusions are: (1) previously reported visual flicker differences between depressed patients and normal controls were probably due to the more conservative response criterion of the patients and not to flicker sensitivity differences between groups; and (2) confidence ratings and response times yield similar conclusions with respect to visual flicker sensitivity and response criterion. Therefore, interpretations concerning a sensory or perceptual deficit in depression must take into account the differences in response criterion between depressed patients and normal controls.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
F. Behrens ◽  
J. A. Snijdewint ◽  
R. G. Moulder ◽  
E. Prochazkova ◽  
E. E. Sjak-Shie ◽  
...  

AbstractCooperation is pivotal for society to flourish. To foster cooperation, humans express and read intentions via explicit signals and subtle reflections of arousal visible in the face. Evidence is accumulating that humans synchronize these nonverbal expressions and the physiological mechanisms underlying them, potentially influencing cooperation. The current study is designed to verify this putative linkage between synchrony and cooperation. To that end, 152 participants played the Prisoner’s Dilemma game in a dyadic interaction setting, sometimes facing each other and sometimes not. Results showed that synchrony in both heart rate and skin conductance level emerged during face-to-face contact. However, only synchrony in skin conductance levels predicted cooperative success of dyads. Crucially, this positive linkage was strengthened when participants could see each other. These findings show the strong relationship between our bodily responses and social behavior, and emphasize the importance of studying social processes between rather than within individuals in real-life interactions.


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