scholarly journals Generic clozapine: outcomes after switching formulations

2006 ◽  
Vol 189 (2) ◽  
pp. 184-185 ◽  
Author(s):  
Carol Paton

SummaryTwo generic preparations of clozapine have been licensed in the UK. The bioequivalence of these products compared with Clozaril® has not been unequivocally demonstrated. Clinical equivalence has also been questioned. The objective of this study was to determine clinical outcomes for all patients switched from Clozaril® to a generic formulation in one mental health service. We examined dosage data and Clinical Global Impression (CGI) of Severity of Illness scores for 337 patients before and after the switch and CGI change scores after the switch. There was no evidence of clinical deterioration or need to use higher dosages. Generic clozapine is not inferior to Clozaril®.

2018 ◽  
Vol 6 (2) ◽  
pp. 728-744 ◽  
Author(s):  
Diana Rose

This commentary concerns how the organisation of State welfare benefits in the UK have changed over the last 20 years, arguing that this has had harmful, even fatal, consequences for people with disabilities and particularly those with mental distress of psychosocial disabilities. This current situation may be called that of austerity. The paper describes how a ‘hidden activism’ has emerged to contest this situation and explains why it is, and to a degree, must be hidden. I then focus on the discourse of responsibilisation where every citizen must take responsibility for embodying the virtues of the good, working person. To ensure this, unemployment has been framed as a psychological problem and psychologists are now employed to ‘treat’ this problem in order that everybody might enter the world of work. I argue that in current conditions this is not possible for all with mental distress. Engaging then with community psychology, I address the issue of allies and how the absence of attention to mental distress might be remedied by this form of work. I draw on the emerging field of user / survivor-led research in mental health and argue that collaboration with community psychology will not be without problems.


Author(s):  
Lynn Tang

This chapter focuses on Chinese mental health service users in the UK and aims to illustrate how structural inequalities shape their recovery journeys. It starts with a discussion of the Recovery Approach with which the research critically engaged. It then introduces the diversity within the Chinese community in the UK. It selects two stories from the research to shed light on how, for UK Chinese people, inequalities such as class, gender, and ethnicity intersect at national and transnational levels, and impact on the way recovery journeys unfold. Such inequalities contribute to their distress and ill-health in the first place and could hinder their recovery. The implications for community development work with Chinese communities are then discussed.


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