scholarly journals Effect of adding bezafibrate to standard lipid-lowering therapy on post-fat load lipid levels in patients with familial dysbetalipoproteinemia. A randomized placebo-controlled crossover trial

2017 ◽  
Vol 58 (11) ◽  
pp. 2180-2187 ◽  
Author(s):  
Charlotte Koopal ◽  
A. David Marais ◽  
Jan Westerink ◽  
Yolanda van der Graaf ◽  
Frank L. J. Visseren
Keyword(s):  
Crossover Trial ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Lipid Levels ◽  
Lowering Therapy ◽  
Familial Dysbetalipoproteinemia

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease

2008 ◽  
Vol 9 (10) ◽  
pp. 1475-1486 ◽  
Author(s):  
Tuomo Nieminen ◽  
Mika Kähönen ◽  
Leena E Viiri ◽  
Paula Grönroos ◽  
Terho Lehtimäki
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Apolipoprotein E ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Lipid Levels ◽  
E Gene ◽  
Lowering Therapy ◽  
Apolipoprotein E Gene

Effect of Lipid Levels and Lipid-Lowering Therapy on Restenosis after Coronary Artery Stenting

2006 ◽  
Vol 331 (5) ◽  
pp. 270-273 ◽  
Author(s):  
Stamatios Lerakis ◽  
Mikhael F. El-Chami ◽  
Amar D. Patel ◽  
Emir Veledar ◽  
Elias Alexopoulos ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Lipid Levels ◽  
Lowering Therapy ◽  
Coronary Artery Stenting

scholarly journals Familial dysbetalipoproteinemia: highly atherogenic and underdiagnosed disorder

2021 ◽  
Vol 20 (6) ◽  
pp. 2893
Author(s):  
A. V. Blokhina ◽  
A. I. Ershova ◽  
A. N. Meshkov ◽  
O. M. Drapkina
Keyword(s):  
Genetic Basis ◽  
Clinical Course ◽  
Full Range ◽  
Lipid Lowering ◽  
Evidence Based ◽  
Clear Understanding ◽  
Lipid Lowering Therapy ◽  
Actual Clinical Practice ◽  
Lowering Therapy ◽  
Familial Dysbetalipoproteinemia

Familial dysbetalipoproteinemia (FD) is a genetic, highly atherogenic disorder. The penetrance of FD depends on the patient’s lifestyle and concomitant diseases. Despite the fact that FD was described almost half a century ago, it is still insufficiently studied and is extremely rarely diagnosed. In actual clinical practice, physicians do not have clear understanding of clinical course and genetic basis of FD. The aim was to present the most complete, but at the same time a critical review with a modern view on FD. We analyzed Russian and foreign publications from following electronic databases: PubMed, eLIBRARY, Google Scholar. As a result, the phenotypic features and genetic variability of the disease were considered and the main issues of diagnosis and treatment of patients with FD were discussed. The data presented will help the clinician to timely suspect the FD, conduct a full range of investigations and prescribe evidence-based lipid-lowering therapy.

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