Esthesioneuroblastoma (ENB): A case report

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 15546-15546
Author(s):  
E. Troncoso ◽  
S. Bonicatto ◽  
A. Mainella ◽  
A. Barbero ◽  
M. Lavezzaro ◽  
...  

15546 Background: ENB is a rare embrionary tumor derived from neuroblasts of the olfactory sensory system. Polypoid mass with epistaxis or nasal obstruction are the most common clinical manifestations of this tumor. It’s invasive and it frequently causes regional and distant metastasis. ENB requires a multimodality therapy. The objective of this study is to describe the form of presentation, diagnosis, treatment and evolution of this tumor on a female patient (pt), as a casuistic contribution. Methods and Case Report: A 61 year old woman with a four month history of epistaxis, nasal pain and anosmia. CT shows nasal mass invading the entire nasal cavity and upper maxillary. Pt underwent nasal resection and reconstruction with frontal flaps. Anatomopathology: ENB invading the bone. Cromogranin (+), sinaptofisin (+), CK (−), NSE (−). Three months later: lesion on the right wing nasal and a mass in the soft palate. MRI: mass on the floor of the nasal fossa that involve the left maxillary sinus and the bone palate. Kadish stage C. We treated her with three cycles of chemotherapy using cisplatin 30 mg/sqM d 1–3 iv and etoposide 100 mg/sqM d 1–3 iv. After that, remission was observed in the wing nasal lesion but the the soft palate mass shows progression. MRI: mass in nasal fossa that destroys the left maxillary sinus and causes lysis of the upper maxillary and orbital floor. Pt was treated with radiotherapy (6000 cGy) showing complete remission of the nasal lession and partial response on the soft palate, verified by physical examination and RMI. Four months after the end of radiotherapy, she continues under control and maintains the response to therapy without evidence of progression. Conclusion: ENB is an unfrequent tumor without any standard treatment. In our case, the combination of surgery, CH and RT has been effective for local control of the disease with good tolerance and acceptable quality of life. No significant financial relationships to disclose.

2020 ◽  
Vol 10 (38) ◽  
pp. 63-65
Author(s):  
Muhammad Adzha Musa ◽  
Ahmad Nordin Affandi ◽  
Prepageran Narayanan ◽  
Tan Shi Nee

AbstractBACKGROUND. Polyps, cysts and mucocele are the commonest sinonasal tumors present unilaterally, as well as invasive tumors, such as inverted papillomas and squamous cell carcinomas. On the contrary, Schwannomas are rare lesions found in this area.MATERIAL AND METHODS. We present a case of a 48-year-old female who presented with a 2-year progressive history of left nasal obstruction, cranio-facial fullness sensation and pain, with intermittent epistaxis. The CT scan of the nose and paranasal sinuses showed complete opacification of the entire left nasal cavity and maxillary sinus, causing a deviated nasal septum to the right side.RESULTS. The tumor was completely excised endoscopically without any complication. Histopathology was consistent with that of a schwannoma.CONCLUSION. The diagnosis of sinonasal Schwannomas remains challenging, as it is a rare tumor and sometimes its clinical behaviour and imaging may be misleading. The treatment of choice for paranasal sinus schwannoma is complete excision of the tumor with good prognosis.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1985741
Author(s):  
Mark G Kirchhof ◽  
Se Mang Wong

The prevalence of tattoos is increasing and as such every physician must be aware of the potential adverse events associated with tattooing. Here we present a 36-year-old man with a recent history of skin-coloured papules appearing suddenly in a 20-year-old tattoo on the right forearm. Biopsy and histologic examination confirmed a diagnosis of verrucae planae or flat warts. Tattoo-associated human papilloma virus infections develop clinical manifestations after long latency periods and are often difficult to treat. The risk of tattoo-related human papilloma virus infection should be discussed when considering acquiring a tattoo.


Ciencia Unemi ◽  
2018 ◽  
Vol 11 (26) ◽  
pp. 150
Author(s):  
Enrique-Javier Lucas ◽  
Alma Amalia Grinstein ◽  
Jorge Cervantes-Coka ◽  
Diana Montoya-Estrada ◽  
Agostina Bonzani ◽  
...  

Demostrar la importancia de la Tomografía computarizada (TC) y Resonancia Magnética (RM) en el diagnóstico, extensión y seguimiento de los pacientes con papiloma invertido (PI). Paciente femenino de 64 años, con antecedentes de sinusitis alérgica recurrente, que consulta por obstrucción nasal bilateral a predominio izquierdo, asociada a rinorrea purulenta y rinolalia de cinco meses de evolución. Se le realiza TC y RM de Macizo Cráneo facial (MCF). La TC demuestra formación de densidad de partes blandas ubicada en fosa nasal y seno maxilar derecho que se extiende hacia celdillas etmoidales bilaterales, seno frontal y seno esfenoidal derecho. La RM evidencia lesión expansiva sólida ubicada sobre seno maxilar derecho, que se extiende excavando la pared interna del mismo hacia fosa nasal homolateral. El PI es una neoplasia nasal que se caracteriza por su crecimiento invertido hacia el estroma. Es un tumor benigno que presenta una incidencia anual del 1 % promedio por cada 100.000 habitantes. La TC es el método imagenológico de elección para el diagnóstico de PI, siendo también útil en la valoración de la extensión en la fase preoperatoria. El diagnóstico de certeza lo determina la histopatología. La RM representa un método de gran utilidad en el seguimiento postoperatorio. AbstractDemonstrating the importance of Computed Tomography (CT) and Magnetic Resonance (MRI) in the diagnosis, extension and follow-up of patients with inverted papilloma (IP) of a 64-year-old female patient with a history of recurrent allergic sinusitis who consults for bilateral nasal obstruction and left predominance associated with purulent rhinorrhea and rhinolalia of five months of evolution. CT and MRI of CranioFacial Massif (CFM) were performed. CT demonstrated soft tissue density formation located in the nasal fossa and right maxillary sinus extending to bilateral ethmoidal cells, frontal sinus and right sphenoid sinus. MRI showed solid expansive lesion located on the right maxillary sinus, extending through its inner wall to the homolateral nasal fossa. IP is a nasal neoplasm that is characterized by its inverse growth towards the stroma. It is a benign tumor that presents an annual incidence of 1% average per 100,000 inhabitants. CT is the imaging method of choice for the diagnosis of IP, and it is also useful in assessing extension in the preoperative phase. A thorough diagnosis is determined by histopathology. MRI represents a very useful method in postoperative follow-up.


RSBO ◽  
2020 ◽  
Vol 17 (1) ◽  
pp. 69-75
Author(s):  
Andreia Moleta ◽  
Luise Machado Brasil ◽  
Edmar Rafael de Oliveira ◽  
Suyany Gabriely Weiss ◽  
Driele Gontarz ◽  
...  

Displaced dental implants into the maxillary sinus are relatively rare. Treatment consists of implant surgical removal. Objective: To present two case reports of the removal of implants displaced into maxillary sinus by a conservative technique. Case report: Report 1: A 44-year-old female sought for treatment complaining about headaches and recurrent sinusitis. In the anamnesis she reported she had been undergone placement of nine maxillary implants, fifteen years ago, with total loss of those elements. At the imaging exams it was possible to observe two displaced implants into the bilateral maxillary sinus, besides radiopaque image on the left maxillary sinus, compatible with maxillary sinusitis. Based on this data, the proposed treatment plan was the removal of the displaced implants through Caldwell Luc approach and sinusotomy in the left side, under general anesthesia. The patient has a follow-up of 6 months without complaints. Report 2: A 42-year-old male was referred to the Surgery and Maxillofacial Traumatology Department for implant removal from the right maxillary sinus. Patient underwent implant installation in the area around 9 months ago. In the computarized tomography it was possible to diagnose the implant migration into the right maxillary sinus. the proposed treatment plan was the removal of the displaced implant via Caldwell Luc Access by repositioning the bony window and sinusotomy. Results: Patient has been with no complaints at 30 days after surgery. Conclusion: The technique has been shown to be effective in treating the condition.


2017 ◽  
Vol 7 (28) ◽  
pp. 251-255
Author(s):  
Alexis Vuzitas ◽  
Marian Petrica ◽  
Claudiu Manea

Abstract BACKGROUND. Signal void, or the absence of signal on MRI sequences, in the sinonasal region may be encountered in fungal rhinosinusitis cases with the aspect of a pseudo-pneumatized sinus, leading to diagnostic errors. CASE REPORT. We present the case of a 75-year-old woman referred to our clinic for complete and persistent right-sided nasal obstruction. The patient was evaluated using sinus CT and contrast-enhanced head MRI. Opacification of the right maxillary, ethmoid and frontal sinuses as well as of the right nasal fossa were seen on CT, with maxillary sinus expansion and osseous erosion. The MRI showed T2 signal void in the maxillary sinus with extension to the nasal fossa, creating the appearance of a pseudo-pneumatized sinus, and hyperintense signal in the ipsilateral anterior ethmoid and frontal sinuses. The patient underwent endoscopic sinus surgery. The dual imaging evaluation of the patient aided the preoperative differential diagnosis and choosing the surgical approach.


VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110030
Author(s):  
Asfandyar Mufti ◽  
Muskaan Sachdeva ◽  
Khalad Maliyar ◽  
Marissa Joseph

Background: Hereditary haemorrhagic telangiectasia is an autosomal dominant genetic disorder characterized by abnormalities in blood vessel formation. The clinical manifestations of patients affected with hereditary haemorrhagic telangiectasia include mucocutaneous telangiectasias and visceral arteriovenous malformations. Case Summary: We report the case of a 30-year-old female diagnosed with hereditary haemorrhagic telangiectasia presenting with the classic triad of recurrent epistaxis, mucocutaneous telangiectasias and family history of hereditary haemorrhagic telangiectasia with activin receptor-like kinase 1 mutation. Upon skin examination, she was noted to have telangiectasias under left naris, inner lower lip and surface of the tongue, and a vascular malformation on the right forearm. Conclusion: Although the skin involvement and epistaxis may be mild symptoms and signs of hereditary haemorrhagic telangiectasia, timely recognition of these can ensure vigilant monitoring of potential severe complications from cerebral and pulmonary visceral arteriovenous malformations.


2021 ◽  
pp. 1-5
Author(s):  
Maya Kornowski Cohen ◽  
Liron Sheena ◽  
Yair Shafir ◽  
Vered Yahalom ◽  
Anat Gafter-Gvili ◽  
...  

SARS-CoV-2 has been reported as a possible triggering factor for the development of several autoimmune diseases and inflammatory dysregulation. Here, we present a case report of a woman with a history of systemic lupus erythematosus and antiphospholipid syndrome, presenting with concurrent COVID-19 infection and immune thrombotic thrombocytopenic purpura (TTP). The patient was treated with plasma exchange, steroids, and caplacizumab with initial good response to therapy. The course of both TTP and COVID-19 disease was mild. However, after ADAMTS-13 activity was normalized, the patient experienced an early unexpected TTP relapse manifested by intravascular hemolysis with stable platelet counts requiring further treatment. Only 3 cases of COVID-19 associated TTP were reported in the literature thus far. We summarize the literature and suggest that COVID-19 could act as a trigger for TTP, with good outcomes if recognized and treated early.


Author(s):  
Benjamin Brunson

ABSTRACT A 10 yr old spayed female toy poodle was presented to a tertiary referral center for a 10 day history of waxing and waning lethargy, vomiting, diarrhea, and anorexia. An immune-mediated neutropenia (IMN) was suspected to be the underlying cause of her clinical signs. A bone marrow aspirate was obtained from the chostochondral junction of the 11th and 12th ribs on the right side and provided a definitive diagnosis of IMN. A positive response to therapy and repeat blood work further confirmed the diagnosis. Obtaining bone marrow aspirates from the chostochondral junction is a safe, cheap, and reliable method of diagnosing IMN and can be performed in the private practice setting with light sedation and minimal need for specialized equipment.


2007 ◽  
Vol 65 (2b) ◽  
pp. 536-539 ◽  
Author(s):  
Taiza E.G. Santos-Pontelli ◽  
Octávio M. Pontes-Neto ◽  
José Fernando Colafêmina ◽  
Dráulio B. de Araújo ◽  
Antônio Carlos Santos ◽  
...  

We report a sequential neuroimaging study in a 48-years-old man with a history of chronic hypertension and lacunar strokes involving the ventral lateral posterior nucleus of the thalamus. The patient developed mild hemiparesis and severe contraversive pushing behavior after an acute hemorrhage affecting the right thalamus. Following standard motor physiotherapy, the pusher behavior completely resolved 3 months after the onset and, at that time, he had a Barthel Index of 85, although mild left hemiparesis was still present. This case report illustrates that pushing behavior itself may be severely incapacitating, may occur with only mild hemiparesis and affected patients may have dramatic functional improvement (Barthel Index 0 to 85) after resolution pushing behavior without recovery of hemiparesis.


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