Prochlorperazine and 5HT3 antagonists for the treatment of breakthrough chemotherapy-induced nausea and vomiting occurring despite prophylactic antiemetic therapy.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. e19590-e19590
Author(s):  
J. M. Jones ◽  
R. Qin ◽  
A. Bardia ◽  
B. Linquist ◽  
S. L. Wolf ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Antiemetic Therapy ◽  
5Ht3 Antagonists

scholarly journals Corticosteroids, the oldest agent in the prevention of chemotherapy-induced nausea and vomiting: What about the guidelines?

2016 ◽  
Vol 4 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Florence Van Ryckeghem
Keyword(s):  
Cost Effective ◽  
Daily Practice ◽  
Patient Characteristics ◽  
Optimal Level ◽  
Chemotherapeutic Agents ◽  
Nausea And Vomiting ◽  
Antiemetic Therapy ◽  
Receptor Antagonists ◽  
Treatment Research ◽  
Antiemetic Agents

AbstractChemotherapy-induced nausea and vomiting (CINV) remains one of the most disturbing side effects of cancer treatment. Research in antiemetic therapy has progressed gradually since the early eighties, and the development of antiemetic agents continues. This review focuses on the current management of CINV based on the most recent guidelines, and adherence to the latter is examined more carefully. Setrons (5HT3 receptor antagonists), corticosteroids, and NK-1 receptor antagonists are the cornerstones of antiemetic therapy. Corticosteroids are one of the oldest agents in the prevention of CINV. They are highly effective, increase the effect of other antiemetic agents, and are cost-effective. The latest developed 5HT3 receptor antagonist palonosetron led to an update of the guidelines of CINV. Other types include benzodiazepines, cannabinoids, and olanzapine. Various factors contribute to the overall risk of developing CINV, such as patient characteristics, emetogenic potency of the chemotherapeutic agents, and correct prevention of CINV. Current guidelines determine which is the right preventive regimen for each cancer patient at risk for experiencing CINV. Adherence to these guidelines and implementation in daily practice seem to be below the optimal level. In Belgium, authorities use the guidelines as a base for reimbursement and this has increased the level of implementation.

scholarly journals Antiemetics for Chemotherapy-Induced Nausea and Vomiting Occurring Despite Prophylactic Antiemetic Therapy

2011 ◽  
Vol 14 (7) ◽  
pp. 810-814 ◽  
Author(s):  
Jason M. Jones ◽  
Rui Qin ◽  
Aditya Bardia ◽  
Breanna Linquist ◽  
Sherry Wolf ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Antiemetic Therapy

Antiemetic Therapy for Nausea and Vomiting in the Emergency Department

2010 ◽  
Vol 39 (3) ◽  
pp. 330-336 ◽  
Author(s):  
Asad E. Patanwala ◽  
Richard Amini ◽  
Daniel P. Hays ◽  
Peter Rosen
Keyword(s):  
Emergency Department ◽  
Nausea And Vomiting ◽  
Antiemetic Therapy

scholarly journals Tropisetron in the prevention of chemotherapy-induced nausea and vomiting in patients responding poorly to previous conventional antiemetic therapy

1993 ◽  
Vol 4 ◽  
pp. S25-S29 ◽  
Author(s):  
U. Bruntsch ◽  
E. Rüfenacht ◽  
I. Parker ◽  
S. Drechsler ◽  
K. de Bruijn
Keyword(s):  
Nausea And Vomiting ◽  
Antiemetic Therapy
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