Patterns of radiation therapy technology use in the treatment of bone metastases.

2016 ◽  
Vol 34 (26_suppl) ◽  
pp. 211-211
Author(s):  
Matthew Chan ◽  
Robert Anton Olson ◽  
Shilo Lefresne ◽  
Michael R. McKenzie
Keyword(s):  
British Columbia ◽  
Radiation Therapy ◽  
Bone Metastases ◽  
Technology Use ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Conformal Radiation Therapy ◽  
Lung Cancers ◽  
Significant Difference ◽  
3D Crt

211 Background: In recent years, there has been a transition from two-dimensional radiation therapy (2DRT) planning towards more advanced techniques such as three-dimensional conformal radiation therapy (3D-CRT), volumetric modulated arc therapy (VMAT), and stereotactic body radiation therapy (SBRT). Our study aim was to analyze these trends in the treatment of bone metastases. Methods: All patients aged 18 and older who had received palliative intent RT for bone metastases between 2009-2014 and referred to any 1 of 6 regional cancer centers in British Columbia, Canada were reviewed. Summary statistics were used to describe radiation technique patterns. Logistic regression modeling was used to assess the influence of demographic, clinical, and health services variables on receipt of types of RT. Results: We identified 8,059 patients and 15,832 courses of RT; overall, 97.9% of courses were achieved by 2DRT and 2.1% by 3D-CRT, VMAT, or SBRT. Despite the low overall use of advanced techniques, its use was significantly higher in all subsequent years compared to 2009 (p < 0.05 for all years). The median age for patients treated with 2DRT was 67.0 (19-99) versus 66.0 years (19-93) for advanced techniques. There did not appear to be a statistically significant difference in age at the time of treatment start (OR 0.99; 95% CI 0.981-1.00, p < 0.05). Compared to lung cancers, thyroid (OR 9.9; 95% CI 5.197-18.724, p < 0.001) and kidney cancers (OR 3.9; 95% CI 2.508-5.911, p < 0.001) were significantly more likely to be treated with advanced techniques, while breast (OR 0.90; 95% CI 0.621-1.306, p = 0.58) and prostate cancers (OR 0.93; 95% CI 0.613-1.410, p = 0.73) were not any more likely. Compared to the Vancouver center, all other treatment centers in the province were utilizing advanced techniques less frequently. Patients were also more likely to complete RT with 2DRT than with advanced techniques (98.3% versus 95.8%, p < 0.05). Conclusions: The vast majority of treatment of bone metastases is still done by 2DRT in British Columbia. Despite these overall statistics though, a trend towards increasing use of more advanced techniques was observed.

scholarly journals Influence of respiratory movement during regional nodal irradiation after mastectomy for breast cancer: an experimental study

2020 ◽  
Author(s):  
Hosang Jeon ◽  
Yongkan Ki ◽  
Dong Woon Kim ◽  
Wontaek Kim ◽  
Jiho Nam ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Absorbed Dose ◽  
Respiratory Movement ◽  
Radiochromic Film ◽  
Organ Protection ◽  
Conformal Radiation Therapy ◽  
Dose Errors ◽  
3D Crt

Abstract Background This study aimed to evaluate the dosimetric consequences of respiratory movement in postmastectomy radiation therapy (PMRT) including internal mammary nodes (IMNs) between volumetric modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT).Methods An anthropomorphic phantom was used to mimic the chest anatomy of a patient who had undergone mastectomy. Two types of absorbed dose measurements were adopted; a radiochromic film was inserted into a gap between phantom slices at the level of the second IMN and three glass rod dosimeters were placed at the first IMN (IM), chest wall (CW), and left anterior descending (LAD) artery. Respiratory movements with amplitudes of 5 mm (R05) and 10 mm (R10) were simulated using a dynamic platform combined with a motorized jack. To evaluate dose errors caused by respiratory movement, the measured data in the presence and absence of respiratory movement were compared.Results At IM, dose errors were − 2.8% (R05) and − 6.2% (R10) for 3D-CRT and − 4.9% (R05) and − 8.5% (R10) for VMAT. The dose errors in CW were − 0.5% (R05) and − 6.0% (R10) for 3D-CRT and − 1.9% (R05) and − 5.3% (R10) for VMAT. The LAD doses showed very small absolute values. According to film measurements, dose errors of IMN were similar between 3D-CRT and VMAT, but the dose error of the lung was higher in 3D-CRT. The gamma pass rates of VMAT (97% at R05; 88% at R10) were higher than those of 3D-CRT (74% at R05; 59% at R10).Conclusions If the patient maintained shallow to normal breathing, PMRT including IMNs could be implemented with acceptable accuracy. In particular, it was possible to maintain the advantages of VMAT, which enabled high-target coverage and normal organ protection.

Digestive toxicities after palliative three-dimensional conformal radiation therapy (3D-CRT) for cervico-thoracic spinal metastases

2017 ◽  
Vol 26 (6) ◽  
pp. 1897-1903 ◽  
Author(s):  
Guillaume Peyraga ◽  
Delphine Caron ◽  
Thibaut Lizee ◽  
Yann Metayer ◽  
Anne-Lise Septans ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Three Dimensional ◽  
Spinal Metastases ◽  
Conformal Radiation Therapy ◽  
Thoracic Spinal ◽  
3D Crt

scholarly journals Dosimetric Analysis with Intensity-modulated Radiation Therapy for Central Nervous System Irradiation in Patients with Brain Cancer Compared with Three-dimensional Conformal Radiation Therapy Treatment

2019 ◽  
Vol 9 (2) ◽  
pp. 50-54
Author(s):  
Noor S. Omer ◽  
Runak T. Ali
Keyword(s):  
Radiation Therapy ◽  
Optic Nerve ◽  
Brain Cancer ◽  
Three Dimensional ◽  
Intensity Modulated Radiation Therapy ◽  
Optic Chiasm ◽  
Imrt Plan ◽  
Conformal Radiation Therapy ◽  
Dosimetric Analysis ◽  
3D Crt

Intensity-modulated radiation therapy (IMRT) was put as the development of three-dimensional conformal radiation therapy (3D-CRT). The purpose of the present study is to compare the dosimetric analysis of two techniques of radiotherapy (IMRT) and 3D-CRT, which include target volume and organ at risk for both plans. The present study enrolled that nine patients with different types of brain cancer which previously irradiated from November 2018 to May 2019 were selected in Zhianawa Cancer Center in Sulaymaniyah; all cases were planned again by both techniques 3D-CRT and IMRT. IMRT planning provides reducing the dose of both right and left optic nerve mean dose for right optic nerve 13.70 Gy and left 14.93 Gy compared with the 3D-CRT plan (right optic nerve 23.54 Gy and left 19.13 Gy). P = 0.2 for the right optic nerve and P = 0.56 for the left optic nerve were statistically significant. IMRT plan reduces dose to the optic chiasm compared to 3D-CRT plan, the mean dose of optic chiasm for IMRT was 33.37 Gy relative to 3D-CRT which was 34.28 Gy and P = 0.92. IMRT plan was better than 3D-CRT for many organs at risk, especially for optic chiasm and both optic nerve deliver less dose than 3D-CRT.

Vai trò cộng hưởng từ trong lập kế hoạch xạ trị bệnh lý u não tại Bệnh viện Trung ương Huế

2021 ◽  
Author(s):  
Nguyen Tuong Pham
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cone Beam Ct ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Cone Beam ◽  
Resonance Imaging ◽  
Conformal Radiation Therapy ◽  
Arc Therapy ◽  
Magnetic Resonance Imaging Mri ◽  
3D Crt

Mục tiêu: Đánh giá vai trò của cộng hưởng từ (Magnetic Resonance Imaging - MRI) trong mô phỏng lập kế hoạch xạ trị cho bệnh lý u não tại Bệnh viện Trung Ương Huế, đánh giá sự tối ưu, lợi ích của vai trò MRI, các giá trị liều lượng mà u và các cơ quan lành nhận được. Đối tượng và phương pháp: Nghiên cứu 38 bệnh nhân u não được chỉ định xạ trị có chụp cắt lớp vi tính (Computed Tomography-CT) 16 lát cắt Philips và cộng hưởng từ(MRI) 1.5 Tesla Philips tại Trung tâm Ung bướu - Bệnh viện Trung Ương Huế từ tháng 01/2018-07/2019. Lập kế hoạch xạ trị gia tốc bằng phần mềm XiO 5.10 đối với kỹ thuật xạ trị 3D-CRT (Three Dimensional - Conformal Radiation Therapy), và phần mềm Monaco 5.11 đối với các kỹ thuật xạ trị hình cung điều biến liều theo thể tích khối u (Volumetric Modulated Arc Therapy-VMAT), Xạ phẫu gồm SRS và SRT (Stereotactic radiosurgery, Stereotactic radiotherapy). Chụp Cone beam CT kiểm tra trước khi điều trị bởi thiết bị hướng dẫn hình ảnh XVI. Điều trị trên máy gia tốc AXESSE (Elekta). Kết quả và bàn luận: 38 bệnh nhân có khối u ở não (u nguyên phát và u di căn) MRI giúp phát hiện thêm các tổn thương 39,5% và 55,3% phát hiện rõ ranh giới u, tất cả những thương tổn u mà CT rất khó phân biệt với mô lành và tổn thương phù não. Kết luận: Ứng dụng hình ảnh MRI trong mô phỏng lập kế hoạch xạ trị gia tốc cho các bệnh lý u não giúp phát hiện và xác định kích thước, thể tích u tốt hơn so với CT mô phỏng. Từ đó sẽ làm thay đổi kế hoạch xạ trị đem lại kết quả điều trị tốt hơn và cải thiện chất lượng sống tốt hơn cho bệnh nhân

Comparison of dosimetry parameters of three-dimensional conformational radiation therapy and volumetric modulated arc therapy on the example of treatment of a patient with salivary gland adenocarcinoma

2021 ◽  
Vol 59 (1) ◽  
pp. 25-30
Author(s):  
A. Rakhimov ◽  
M. Zekebayev ◽  
A. Kuatbek ◽  
V. Dyachkov
Keyword(s):  
Radiation Therapy ◽  
Salivary Gland ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Optimal Choice ◽  
International Standards ◽  
Salivary Gland Cancer ◽  
Conformal Radiation Therapy ◽  
Dose Load ◽  
Arc Therapy

An optimal choice of radiation therapy method is the main prerequisite for successful completion of treatment. Continuous analysis of radiation therapy methods’ advantages and comparing their parameters and dose load in typical cases will increase the treatment efficacy and reduce the unavoidable load on critical organs. The purpose was to check the plans of treatment by volumetric modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT) methods, make their comparison and identify the advantages using an example of a treatment design for a patient treated at the Daily Radiotherapy Hospital of the Kazakh Institute of Oncology and Radiology (Almaty, Kazakhstan). Results: The presented illustrations of the process planning and the numerical analysis of the dose load on critical organs show VMAT advantages for radiation therapy of salivary gland cancer: optimal coverage, sparing load on critical organs and healthy tissues, gradient decay at the borders of the neoplasm. Conclusion: The variability of radiation therapy methods ensures the most acceptable coverage that keeps the dose load within international standards’ ranges. Mastering these methods will improve the effectiveness of radiation therapy for various cancer cases

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