Health utility scores (HUS) and health-related quality of life (HRQoL) in stage 4 lung cancer (S4LC) patients with brain metastases (BM).

2017 ◽  
Vol 35 (8_suppl) ◽  
pp. 24-24 ◽  
Author(s):  
Vivian Tam ◽  
Brandon C Tse ◽  
Tiffany Tse ◽  
Lin Lu ◽  
Emily Tam ◽  
...  
Keyword(s):  
Health Utility ◽  
Well Being ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Stage 4 ◽  
Related Quality ◽  
Health Related ◽  
Economic Analyses ◽  
Age Range

24 Background: Novel therapies have improved the survival of S4LC patients, particularly those with EGFR or ALK alterations. As BM are common among such patients, determining whether HUS appropriately capture BM-specific HRQoL is crucial in economic analyses. We evaluated the relationship between the FACT-Brain (Br) HRQoL, presence of BM, and HUS. Methods: This cross-sectional study of S4LC outpatients at a comprehensive cancer centre assessed FACT-Br and EQ-5D-3L-derived HUS. Correlational analyses, stratified by BM status, were performed between HUS and each of FACT-Br and its subscales: FACT-General (G), physical well-being (PWB), social well-being (SWB), emotional well-being (EWB), functional well-being (FWB), and brain cancer (BrC). Linear regression interaction models assessed whether BM modified the associations between FACT-Br or its subscales and HUS. Results: The 65 BM and 42 non-BM patients had similar demographics: median age (range) was 62 (30-83) years, 61% were female, 55% were Caucasian, and 54% were EGFR/ ALK+. Mean± standard error of the mean (SEM) values of HUS were similar between BM and non-BM groups (0.77±0.02 vs. 0.78±0.02; p=0.49). However, 40 BM patients with stable brain disease had higher HUS than the 14 with progressive disease (0.81 vs. 0.69; p=0.007). Mean±SEM values for FACT-Br, FACT-G, and BrC were 148±2.6, 79±1.5, and 69±1.3, respectively, with no differences between BM and non-BM groups. With the exception of SWB, FACT-Br and its subscales were each individually correlated with HUS (all p<0.001 unless specified), including between HUS and PWB (all patients: r=0.58; BM only: r=0.60; non-BM only: r=0.54), FACT-Br (all: r=0.55; BM: r=0.55; non-BM: r=0.54), FACT-G (all: r=0.51; BM: r=0.49; non-BM: r=0.55), and BrC (all: r=0.49; BM: r=0.51; non-BM: r=0.44, p=0.003). Having BM did not modify these relationships (each interaction, p>0.35). Conclusions: The FACT-Br HRQoL measures and the majority of its subcomponents moderately correlate with HUS but are not specific to patients with BM. Progression of CNS disease greatly alters HUS. EQ-5D-3L-derived HUS are a useful index of HRQoL in S4LC.

scholarly journals Cyberbullying in Gifted Students: Prevalence and Psychological Well-Being in a Spanish Sample

2019 ◽  
Vol 16 (12) ◽  
pp. 2173 ◽  
Author(s):  
González-Cabrera ◽  
Tourón ◽  
Machimbarrena ◽  
Gutiérrez-Ortega ◽  
Álvarez-Bardón ◽  
...  
Keyword(s):  
Gifted Students ◽  
Well Being ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Psychological Variables ◽  
Related Quality ◽  
Health Related

The differential characteristics of gifted students can make them vulnerable to cyberbullying. There is very little empirical evidence about cyberbullying and giftedness. In the Spanish context, it is unexplored. The main goal of this work is to determine the prevalence of cyberbullying, its distribution in the different roles, and its relationship with other psychological variables. A cross-sectional study was performed with 255 gifted students (M = 11.88 years, SD = 2.28 years) in Spain (155 males, 60.8%). We used the cyberbullying test and the Spanish versions of the DASS-21, ISEL, KIDSCREEN-10, and the SWLS. The results indicate that 25.1% of the students are pure-cybervictims, 3.9% pure-cyberbullies, and 6.6% cyberbully-victims. Pure-cybervictims and cyberbully-victims present worse scores (p < 0.001) in health-related quality of life, depression, life satisfaction and stress than the uninvolved individuals. The results suggest that the gifted sample presents more cybervictimization and less cyberbullying than observed in other studies of the general population.

scholarly journals Periodontal Status and Oral Health-Related Quality of Life among Elderly attending Kantipur Dental College, Kathmandu, Nepal

2017 ◽  
Vol 1 (2) ◽  
pp. 46-50 ◽  
Author(s):  
Anju Khapung ◽  
G. Nagaraja Rao ◽  
Sujita Shrestha ◽  
Bhageshwar Dhami
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Well Being ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Periodontal Status ◽  
Related Quality ◽  
Health Related

Background: In elderly, poor oral health in the form of tooth loss, dental caries, periodontal disease and oral cancer affects physical and psychological aspect of life. Health is not only absence of disease but also psychological and social well-being. Thus, the assessment of disease by clinical examination as well as measurement of psychosocial impacts associated with disease are equally important. Aim: To find the association between periodontal status and oral health-related quality of life among elderly attending Kantipur Dental College. Materials and Methods: A cross-sectional study was carried out among 184 elderly patients attending Kantipur Dental College by convenient sampling method. Oral health-related quality of life was assessed by GOHAI. Periodontal status was assessed by using CPI modified and Loss of attachment. Data was analysed with SPSS version 20. Results: Among 184 total participants (74 men, 110 women), the mean GOHAI score was 46.59+8.70. Of the total, 13% had high GOHAI score whereas 27% had moderate and 60% had low GOHAI score. Periodontal status of elderly population was found to be significantly associated with oral health-related quality of life (p<0.05). Conclusion: The findings of this study suggest a need to improve oral health care and knowledge for elderly group through preventive and curative public health measures.  

scholarly journals Relationship between Weight Status and Health-Related Quality of Life in a Sample of Early Adolescents from Central and Northern Italy: A Cross-Sectional Study of the AVATAR Project Participants

2021 ◽  
Vol 18 (16) ◽  
pp. 8782
Author(s):  
Francesca Mastorci ◽  
Paolo Piaggi ◽  
Cristina Doveri ◽  
Gabriele Trivellini ◽  
Irene Marinaro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Status ◽  
Well Being ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Among the various factors that could influence health-related quality of life (HRQoL) in adolescence, body mass index (BMI) seems to play a key role as a main anthropometric parameter. The aim of this cross-sectional study was to determine, in a sample of Italian adolescents, whether HRQoL is associated with the different weight status categories (underweight, normal weight, overweight, obese), according to BMI cut-off points for children, even considering sex differences. Data were collected from 1707 adolescents (n = 828 males) in seven schools. HRQoL was analyzed using the Italian version of KIDSCREEN-52. Males were more overweight and obese than females (13% vs. 10% and 4% vs. 2%, p < 0.05, respectively). In females, BMI categories are associated with physical well-being (p < 0.05), emotion/mood (p < 0.05), self-perception (p < 0.001), financial resources (p < 0.05), and bullying behavior (p < 0.05). In males, weight status is linked to physical well-being dimension (p < 0.001) and perception of self (p < 0.05). Our results may suggest that there is an association between weight status categories and HRQoL, more pronounced in females than in males. Interestingly, the weight status correlated more with the psychological dimension mainly in females, whereas in males, a stronger association between weight and physical status was observed, suggesting that given the complex, multifaceted, and dynamic nature of relationship between health-related quality of life and weight status in adolescents, multiple factors must be considered.

scholarly journals Relevant Factors in Adolescent Well-Being: Family and Parental Relationships

2021 ◽  
Vol 18 (14) ◽  
pp. 7666
Author(s):  
Raquel M. Guevara ◽  
José E. Moral-García ◽  
José D. Urchaga ◽  
Sergio López-García
Keyword(s):  
Quality Of Life ◽  
Family Environment ◽  
International Study ◽  
Well Being ◽  
Cross Sectional Study ◽  
Parental Relationships ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Health-related quality of life, teachers’ opinion of academic performance and self-perceived health are indicators of well-being in the adolescent stage. Some variables, such as those related to the quality of family and parental relationships, may influence these indicators and thus condition well-being during this stage of life and beyond. In this research, the aforementioned variables are analyzed jointly. It is a cross-sectional study in which 1375 adolescent schoolchildren between 11 and 18 years of age participated. Different instruments such as KIDSCREEN-10 and the questionnaire used in the international study Health Behaviour in School-Aged Children were used. The results obtained allow us to conclude that HRQoL, the teacher’s opinion of performance and the perception of health status improve as adolescents perceive a more favorable family climate, also helped by good relations between parents. Finally, it is proposed to continue with the efforts made in the school, family environment and other areas because of the enormous potential for generating quality of life in the adolescent stage and the consequent positive repercussions this has on adulthood.

Health related quality of life of rosacea patients in China assessed by DLQI and willingness to pay: Cross-Sectional Questionnaire Study (Preprint)

2020 ◽  
Author(s):  
Yaqun Huang ◽  
Sha Yan ◽  
Hongfu Xie ◽  
Ben Wang ◽  
Zhixiang Zhao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Willingness To Pay ◽  
Disease Duration ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

BACKGROUND Rosacea is a chronic inflammatory dermatosis with facial skin involved, leading to physical and emotional problems, which greatly affected quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. OBJECTIVE To investigate HRQoL in Chinese rosacea patients assessed by DLQI and WTP and investigate potential predictors for patients with HRQoL severely affected. METHODS This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. RESULTS 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of $1050.2 or € 896.2 (median $431.4 or € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI (P < .05). DLQI could be independently impacted by age (21-30 and 31-40, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), oedema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. CONCLUSIONS The QoL was negatively affected and should not be ignored among rosacea patients in China. Patients aged 21-40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related symptoms were more likely to have severe or very severe limitation of QoL.

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