Diabetes Mellitus/Anti-DM Pharmacological Management

2020 ◽  
pp. 159-173
Author(s):  
Bogdan Bumbăcilă ◽  
Corina Duda-Seiman ◽  
Daniel Duda-Seiman ◽  
Mihai V. Putz
Keyword(s):  
Diabetes Mellitus ◽  
Pharmacological Management

scholarly journals Pharmacological Management Evolution of Type 2 Diabetes Mellitus: Focus on Cardiovascular Outcomes Trials from 2013 to 2020 and Their Impact on Practice Guidelines

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Morales-Villegas EC
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Practice Guidelines ◽  
Pharmacological Treatment ◽  
Cardiovascular Outcomes ◽  
Renal Protection ◽  
Pharmacological Management ◽  
The World

In this brief review of the recent evolution of the pharmacological treatment of Type 2 Diabetes Mellitus (T2DM), we will analyze how different ways of living with diabetes coexist around the world. To define them, we will use the concept that we have called the three contemporary visions of T2DM, namely: dark vision, luminous vision, and bright vision. We will also discuss how the glucocentric paradigm of T2DM treatment led to the development, implementation, and publication of the Cardiovascular Outcomes Trials (CVOTs) in T2DM. Since June 2013, eighteen CVOTs have been published that have studied the cardiovascular safety of fifteen anti-diabetic drugs belonging to four new therapeutic classes. Together, these studies have included more than 150,000 individuals with a cumulative average follow-up of almost half a million patient-years. These studies have shown that beyond glycemic control, six drugs-Empagliflozin, Canagliflozin, Dapagliflozin, Liraglutide, Semaglutide, and Dulaglutide belonging to two new therapeutic classes, significantly reduce the cerebrovascular, cardiovascular, and renal morbidity and mortality of T2DM patients. Thus, establishing a new paradigm in the pharmacological treatment of T2DM, the paradigm of cerebral and cardio-renal protection of the diabetic individual. This substantial evidence has been transferred to the T2DM practice guidelines and, for the first time in this medical field, has been homologated around the world.

scholarly journals Dementia diagnosis affects pharmacological management of diabetes mellitus: A matched analysis of ∼20,000 patients from the Swedish registries

2020 ◽  
Vol 16 (S10) ◽  
Author(s):  
Juraj Secnik ◽  
Hong Xu ◽  
Emilia Schwertner ◽  
Niklas Hammar ◽  
Michael Alvarsson ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Dementia Diagnosis ◽  
Pharmacological Management

scholarly journals A Review on Experimental and Clinical studies of Complementary and Alternative Medicine in Prediabetes

2021 ◽  
Vol 68 (1) ◽  
Author(s):  
Sajjanar Jambappa Neelakant
Keyword(s):  
Diabetes Mellitus ◽  
Alternative Medicine ◽  
Complementary And Alternative Medicine ◽  
English Language ◽  
Treatment Modalities ◽  
Term Care ◽  
Pharmacological Management ◽  
Mesh Terms ◽  
Increased Risk ◽  
Complementary And Alternative

Prediabetes or latent phase of Type 2 Diabetes mellitus (ICD 10- R73.03) is associated with increased risk of progressing to manifestation of diabetes. Complementary and alternative medicine (CAM) has a long history of use in certain parts of the world and has gained increasing interest over the last decades globally. CAM includes both Pharmacological and Non-pharmacological treatment modalities and these are sought for management of most of the diseases including metabolic disorders, especially for long term care. Multiple studies have shown the effectiveness of CAM interventions in management of Prediabetes. This review collates and summarises current (as on May 2020) published literature on CAM as a management strategy for Prediabetes. We included articles in English language from PubMed and Scopus databases using appropriate free keywords and MeSH terms related to the topic. Search strategy yielded articles of which few were unrelated to the topic and few were on Diabetes mellitus of both types. In the process of review, we tried to categorise each of the available mode of treatment as pharmacological and non-pharmacological management and collated the available evidence on the same.

Clinical correlates and pharmacological management of Asian patients with concomitant diabetes mellitus and heart failure

2018 ◽  
Vol 23 (3) ◽  
pp. 461-468 ◽  
Author(s):  
Yvonne May Fen Chia ◽  
Tiew-Hwa Katherine Teng ◽  
Chanchal Chandramouli ◽  
Jonathan Yap ◽  
Michael MacDonald ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Pharmacological Management ◽  
Clinical Correlates ◽  
Asian Patients

scholarly journals VISCERAL MOBILIZATION: STATE OF ART FOR SYSTEMIC PATHOLOGIES MANAGEMENT

2021 ◽  
Vol 10 (1) ◽  
pp. 3-5
Author(s):  
Omaima Sohail
Keyword(s):  
Diabetes Mellitus ◽  
Pain Syndrome ◽  
Life Time ◽  
Treatment Method ◽  
Systemic Effects ◽  
Type I ◽  
Systemic Diseases ◽  
Pharmacological Management ◽  
Wide Range

The global disease burden has evident about significant increase in many systemic diseases such as central obesity, diabetes mellitus and atherosclerosis. The concept of invasive and pharmacological management of various systemic diseases has seen a paradigm shift towards conservative management techniques like physical therapy in the last two decades for multiple conditions like type II Diabetes Mellitus, Complex Regional Pain Syndrome Type I, Atherosclerosis, Hypertension and Peripheral Arterial Disease. Multiple exercise guidelines have been created and customized and implemented worldwide to address discussed pathologies. However, it has been observed that the effects of exercises are short term requiring a life time commitment to continue the exercise regimen. Henceforth, the idea of visceral mobilization which is a hands-on treatment method implemented to mobilize the organs brought forward with pronounced systemic effects including angiogenesis and healing of aged or injured tissue along with symptomatic management1. A wide range of systemic effects have been observed with the spinal manipulation and soft tissue mobilization leading to the confirmation of physiological effectiveness of visceral mobilization. Spinal control produces changes in muscle shaft reaction, nocifensive reflex reaction and neuronal movement, electromyography, and immunologic reaction. Further, it is seen to deliver physiological changes including autonomic, circulatory, lymphatic and immunologic capacities, instinctive reaction, quality articulation, neuroanatomy, capacity and pathology, and cell reaction to in vitro recreated massage.

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