scholarly journals Sex-Dependent Metabolic, Neuroendocrine, and Cognitive Responses to Dietary Energy Restriction and Excess

Endocrinology ◽  
2007 ◽  
Vol 148 (9) ◽  
pp. 4318-4333 ◽  
Author(s):  
Bronwen Martin ◽  
Michele Pearson ◽  
Lisa Kebejian ◽  
Erin Golden ◽  
Alex Keselman ◽  
...  
Keyword(s):  
Energy Restriction ◽  
Cognitive Responses ◽  
Dietary Energy ◽  
Dietary Energy Restriction

scholarly journals Cardiometabolic and reproductive benefits of early dietary energy restriction and voluntary exercise in an obese PCOS-prone rodent model

2015 ◽  
Vol 226 (3) ◽  
pp. 193-206 ◽  
Author(s):  
Abdoulaye Diane ◽  
Maria Kupreeva ◽  
Faye Borthwick ◽  
Spencer D Proctor ◽  
W David Pierce ◽  
...  
Keyword(s):  
Cardiometabolic Risk ◽  
Energy Restriction ◽  
Rodent Model ◽  
Voluntary Exercise ◽  
Chow Diet ◽  
Adult Women ◽  
Dietary Energy ◽  
Lean Control ◽  
Dietary Energy Restriction ◽  
Reproductive Indices

Polycystic ovary syndrome (PCOS) is one of the most common endocrine-metabolic disorders in women of reproductive age characterized by ovulatory dysfunction, hyperandrogenism and cardiometabolic risk. The overweight-obese PCOS phenotype appears to have exacerbated reproductive dysfunction and cardiometabolic risk. In overweight-obese adult women with PCOS, exercise and energy restricted diets have shown limited and inconsistent effects on both cardiometabolic indices and reproductive outcomes. We hypothesized that an early lifestyle intervention involving exercise and dietary energy restriction to prevent or reduce the propensity for adiposity would modulate reproductive indices and cardiometabolic risk in an obese PCOS-prone rodent model. Weanling obese PCOS-prone and Lean-Control JCR:LA-cp rodents were given a chow dietad libitumor an energy-restricted diet combined with or without voluntary exercise (4 h/day) for 8 weeks. Dietary energy restriction and exercise lowered total body weight gain and body fat mass by 30% compared to free-fed sedentary or exercising obese PCOS-prone animals (P<0.01). Energy restriction induced an increase in exercise intensity compared to free-feeding plus exercise conditions. Energy restriction and exercise decreased fasting plasma triglycerides and apoB48 concentrations in obese PCOS-prone animals compared to free-fed and exercise or sedentary groups. The energy restriction and exercise combination in obese PCOS-prone animals significantly increased plasma sex-hormone binding globulin, hypothalamic cocaine-and amphetamine-regulated transcript (CART) and Kisspeptin mRNA expression to levels of the Lean-Control group, and this was further associated with improvements in estrous cyclicity. The combination of exercise and dietary energy restriction when initiated in early life exerts beneficial effects on cardiometabolic and reproductive indices in an obese PCOS-prone rodent model, and this may be associated with normalization of the hypothalamic neuropeptides, Kisspeptin and CART.

scholarly journals Does severe dietary energy restriction increase binge eating in overweight or obese individuals? A systematic review

2015 ◽  
Vol 16 (8) ◽  
pp. 652-665 ◽  
Author(s):  
F. Q. da Luz ◽  
P. Hay ◽  
A. A. Gibson ◽  
S. W. Touyz ◽  
J. M. Swinbourne ◽  
...  
Keyword(s):  
Systematic Review ◽  
Binge Eating ◽  
Energy Restriction ◽  
Dietary Energy ◽  
Dietary Energy Restriction

scholarly journals Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain Injury

2019 ◽  
Vol 67 (4) ◽  
pp. 613-621 ◽  
Author(s):  
V. Rubovitch ◽  
A. Pharayra ◽  
M. Har-Even ◽  
O. Dvir ◽  
M. P. Mattson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Mouse Model ◽  
Energy Restriction ◽  
Dietary Energy ◽  
Dietary Energy Restriction

scholarly journals Effect of ultraviolet B radiation on activator protein 1 constituent proteins and modulation by dietary energy restriction in SKH-1 mouse skin

2009 ◽  
Vol 48 (9) ◽  
pp. 843-852 ◽  
Author(s):  
Brian D. Hopper ◽  
Joseph Przybyszewski ◽  
Haw-Wen Chen ◽  
Kimberly D.P. Hammer ◽  
Diane F. Birt
Keyword(s):  
Mouse Skin ◽  
Energy Restriction ◽  
Ultraviolet B ◽  
Dietary Energy ◽  
Activator Protein 1 ◽  
Ultraviolet B Radiation ◽  
Activator Protein ◽  
Dietary Energy Restriction

scholarly journals Effects of Dietary Energy Restriction on Gene Regulation in Mammary Epithelial Cells

2007 ◽  
Vol 67 (24) ◽  
pp. 12018-12025 ◽  
Author(s):  
Z. Zhu ◽  
W. Jiang ◽  
J. N. McGinley ◽  
J. M. Price ◽  
B. Gao ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Epithelial Cells ◽  
Mammary Epithelial Cells ◽  
Energy Restriction ◽  
Mammary Epithelial ◽  
Dietary Energy ◽  
Dietary Energy Restriction

Dietary energy restriction abolishes development of prolactin-producing pituitary tumors in Fischer 344 rats treated with 17-βestradiol

1998 ◽  
Vol 23 (2) ◽  
pp. 86-95 ◽  
Author(s):  
Thomas J. Spady ◽  
Athena M. Lemus-Wilson ◽  
Karen L. Pennington ◽  
Darcy J. Blackwood ◽  
Tanya M. Paschall ◽  
...  
Keyword(s):  
Pituitary Tumors ◽  
Energy Restriction ◽  
Dietary Energy ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Dietary Energy Restriction

Identification of molecular targets for dietary energy restriction prevention of skin carcinogenesis: An idea cultivated by Edward Bresnick

2004 ◽  
Vol 91 (2) ◽  
pp. 258-264 ◽  
Author(s):  
Diane F. Birt ◽  
Joe Przybyszewski ◽  
Weiqun Wang ◽  
Jeanne Stewart ◽  
Y. Liu
Keyword(s):  
Molecular Targets ◽  
Energy Restriction ◽  
Skin Carcinogenesis ◽  
Dietary Energy ◽  
Dietary Energy Restriction
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