Preoperative Serum Thyroid Stimulating Hormone Level in Well Differentiated Thyroid Carcinoma Is Predictive Factor for Lymph Node Involvement.

2010 ◽  
pp. P1-551-P1-551
Author(s):  
JE Huh ◽  
MR Kim ◽  
JY Mok ◽  
YK Jeon ◽  
SS Kim ◽  
...  
Keyword(s):  
Lymph Node ◽  
Thyroid Carcinoma ◽  
Predictive Factor ◽  
Hormone Level ◽  
Lymph Node Involvement ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Stimulating Hormone ◽  
Preoperative Serum ◽  
Node Involvement ◽  
Well Differentiated

scholarly journals Isthmusectomy for well-differentiated thyroid carcinoma located to the isthmus: A report of two cases and review of the literature

Medwave ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. e8493-e8493
Author(s):  
Roberto Ignacio Olmos Borzone ◽  
Jorge Andrés López Ruiz-Esquide ◽  
Francisco Domínguez Covarrubias ◽  
José Miguel Domínguez Ruiz-Tagle
Keyword(s):  
Lymph Node ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Therapeutic Option ◽  
Lymph Node Involvement ◽  
Differentiated Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Node Involvement ◽  
Well Differentiated ◽  
Prophylactic Lymph Node Dissection

Papillary thyroid cancer is the most common endocrine malignancy, and due to its favorable prognosis, the extent of surgery has been a matter of debate. About 10% of these tumors are located in the thyroid isthmus, with no specific management in current guidelines. In the last decades, isthmusectomy has been proposed as a therapeutic option for isthmic papillary thyroid carcinoma, although there is no consensus on its management. We present two cases of patients from our institution with solitary isthmic papillary thyroid carcinoma without clinical macroscopic extrathyroidal extension or clinical-radiological lymph node involvement who were treated with isthmusectomy without prophylactic lymph node dissection. Neither of them had any postoperative complications. Both had an intermediate risk of recurrence due to aggressive variants. None of them had signs of recurrence during follow-up. We intend to show that isthmusectomy seems to be an effective and safe surgical alternative in selected patients through these cases.

Analysis and utility of pretreatment and posttreatment total body iodine-131 scans in patients with thyroid carcinoma

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e17031-e17031
Author(s):  
S. Billan ◽  
H. Nasrallah ◽  
R. Abdah-Bortnyak ◽  
A. Kuten
Keyword(s):  
Thyroid Carcinoma ◽  
Lymph Node Involvement ◽  
Differentiated Thyroid Carcinoma ◽  
Low Risk ◽  
Extracapsular Extension ◽  
Additional Information ◽  
Risk Patients ◽  
Node Involvement ◽  
Well Differentiated ◽  
Total Body

e17031 Background: The purpose of this study was to evaluate the efficacy of post-I-131 treatment total body scans. Methods: The records of 108 consecutive patients with thyroid carcinoma treated by surgery and postoperative I-131 were reviewed. All patients underwent a postoperative diagnostic total body I-131 and post I-131 therapy scintigraphies .83% of patients were considered low risk according to AMES (age, metastasis, extracapsular extension, size) criteria. Results: The postoperative diagnostic total body I-131 scintigraphy revealed uptake in the neck in 95 out of 108 patients (88%). Three patients had lung and mediastinal uptake in known sites of metastatic disease. Additional foci of neck, mediastinal and lung uptake were revealed in the post-131 therapy total body scintigraphies in ten patients ( 9.3%). Variables found to correlate significantly with additional uptake on the post-I131 therapy total body scintigraphies were tumor size >4cm, lymph-node involvement and extracapsular extension. Conclusions: Post- I-131 therapy scans yielded additional information in 9.3% of the patients treated by postoperative I-131 for well differentiated thyroid carcinoma. The value of posttreatment scintigraphies is questionable in low risk patients. No significant financial relationships to disclose.

Tumor Classification in Well-Differentiated Thyroid Carcinoma and Sentinel Lymph Node Biopsy Outcomes: A Direct Correlation

Thyroid ◽  
2014 ◽  
Vol 24 (4) ◽  
pp. 671-674 ◽  
Author(s):  
Anastasios Maniakas ◽  
Veronique-Isabelle Forest ◽  
Yelda Jozaghi ◽  
Joe Saliba ◽  
Michael P. Hier ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Lymph Node Biopsy ◽  
Tumor Classification ◽  
Node Biopsy ◽  
Well Differentiated

scholarly journals Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
A. Bahar Ceyran ◽  
Serkan Şenol ◽  
Barış Bayraktar ◽  
Şeyma Özkanlı ◽  
Z. Leyla Cinel ◽  
...  
Keyword(s):  
Lymph Node ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Langerhans Cell Histiocytosis ◽  
Cervical Lymph Node ◽  
Lymph Node Involvement ◽  
Langerhans Cell ◽  
Papillary Thyroid ◽  
Thyroid Papillary ◽  
Node Involvement

A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion. The patient was operated on. The pathological diagnosis was reported as papillary thyroid carcinoma. The immunohistochemical examination showed multiple foci of Langerhans cell histiocytosis involving both lobes. The patient died due to cardiac arrest with respiratory causes in the early postoperative period. Langerhans cell histiocytosis is a rare primary condition which involves abnormal clonal proliferation of Langerhans cells in various tissues and organs. Thyroid involvement is infrequently seen. Although the etiology is unknown, genetic components may be linked to the disease. It is also associated with a family history of thyroid disease. Papillary thyroid carcinoma is the most common malignant epithelial tumor of the thyroid gland. Langerhans cell histiocytosis presenting with papillary thyroid carcinoma is rare. The privilege of our case is langerhans cell histiocytosis of the thyroid with multiple cervical lymph node involvement accompanying cervical lymph node metastatic thyroid papillary carcinoma.

scholarly journals REGIONAL LYMPH NODE METASTASES IN WELL-DIFFERENTIATED THYROID CARCINOMA

1987 ◽  
Vol 48 (3) ◽  
pp. 295-299
Author(s):  
Masakuni NOGUCHI ◽  
Tetsuya ISHIDA ◽  
Kiyoshi TAJIRI ◽  
Hisatake FUJII ◽  
Itsuo MIYAZAKI
Keyword(s):  
Lymph Node ◽  
Thyroid Carcinoma ◽  
Lymph Node Metastases ◽  
Regional Lymph Node ◽  
Differentiated Thyroid Carcinoma ◽  
Node Metastases ◽  
Well Differentiated

scholarly journals Clinicopathological Profile of Thyroid Carcinoma in Young Patients: An Indonesian Single-Center Study

2022 ◽  
Vol 2022 ◽  
pp. 1-8
Author(s):  
Agnes Stephanie Harahap ◽  
Desty Gusti Sari ◽  
Marini Stephanie ◽  
Alvita Dewi Siswoyo ◽  
Litta Septina Mahmelia Zaid ◽  
...  
Keyword(s):  
Lymph Node ◽  
Mortality Rate ◽  
Thyroid Carcinoma ◽  
Distant Metastasis ◽  
Disease Recurrence ◽  
Lymph Node Involvement ◽  
Common Type ◽  
Thyroid Malignancy ◽  
Node Involvement

Introduction. Thyroid cancer is the third most common cancer that occurs in children and adolescents. Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Although the mortality rate of thyroid malignancy in children is usually low, the disease recurrence is higher in children with more severe clinical presentation than in adults. This study aimed to determine the demographic and clinicopathological characteristics and outcome of pediatric and adolescent patients with thyroid malignancy in Indonesia. Methods. The retrospective study included all patients diagnosed with thyroid carcinoma aged <20 years, from January 1, 2015, to December 31, 2019. Twenty-nine subjects fulfilled the inclusion and exclusion criteria. We retrieved baseline characteristics, pathology features, TSH and fT4 status, radioactive iodine therapy data, and patients’ outcomes. Then, data were analyzed using the chi-square or Fisher’s exact method. Results. We identified 29 eligible subjects, including 3 boys and 26 girls. The most common type of thyroid carcinoma was PTC (96.5%), and follicular type (31%) was the predominant variant of PTC. Lymph node involvement occurred in 24% of patients, while distant metastasis occurred in 17.2% of patients with PTC. Twenty-four (82.7%) patients had stage 1 disease. Disease recurrence was recorded in 31% of patients during the study period with a median follow-up time of 24 months. Conclusion. PTC is the most frequent type of thyroid carcinoma among children and adolescents. This malignancy has a low mortality rate, but the recurrence rate remains high among younger patients than adults even during a short-term follow-up analysis. Distant metastasis and lymph node involvement are commonly found in this age group.

Grading as a Prognostic Factor: Review of 209 Primary Gastric Cancer Patients

1989 ◽  
Vol 75 (5) ◽  
pp. 494-497 ◽  
Author(s):  
Giovanni Battista Secco ◽  
Roberto Fardelli ◽  
Elisabetta Campora ◽  
Salvatore Rovida ◽  
Gabriella Lapertosa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Tumor Grade ◽  
Tumor Stage ◽  
Lymph Node Involvement ◽  
Primary Gastric Cancer ◽  
Node Involvement ◽  
Involvement Rate ◽  
Well Differentiated ◽  
Gastric Cancer Patients

Two hundred and nine cases of primary gastric cancer were treated surgically from January 1968 to December 1983 and analyzed retrospectively. All patients were followed up for a minimum of 5 years. There were 25 SI cases (12 %), 22 SII (10.5%), 55 SIII (26.3%) and 107 SIV (51.2%). Tumor grade according to Broders classification showed 50 cases of G1 lesions (23.9%), 44 G2 (21.1 %) and 115 G3 (55%). Patients with well differentiated G1 lesion, compared to G2-G3 patients, presented a greater incidence of T1-T2 tumors and decreased incidence of T4 tumors (p < 0.05). The lymph node involvement rate significantly increased with variation of T (p < 0.001) but not with tumor grade. Survival results correlated with tumor stage (p < 0.01) but not with tumor grade or histological type.

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