Human fibroblasts secrete a serine protease that cleaves insulin-like growth factor-binding protein-5.

Endocrinology ◽

10.1210/endo.135.4.7523096 ◽

1994 ◽

Vol 135 (4) ◽

pp. 1385-1391 ◽

Author(s):

T J Nam ◽

W H Busby ◽

D R Clemmons

Keyword(s):

Growth Factor ◽

Serine Protease ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

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Faculty Opinions recommendation of Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004704.370795 ◽

2006 ◽

Author(s):

Masaru Nonaka

Keyword(s):

Growth Factor ◽

Serine Protease ◽

Synthetic Peptides ◽

Binding Protein ◽

Insulin Like Growth Factor ◽

Factor Binding ◽

Mannan Binding Lectin ◽

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Regulation of immunoreactive insulin-like growth factor binding protein-6 in normal and transformed human fibroblasts

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)78147-2 ◽

1994 ◽

Vol 269 (15) ◽

pp. 11470-11477

Author(s):

J.L. Martin ◽

J.A. Coverley ◽

R.C. Baxter

Keyword(s):

Growth Factor ◽

Binding Protein ◽

Human Fibroblasts ◽

Immunoreactive Insulin ◽

Insulin Like Growth Factor ◽

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Overexpression of Insulin-like Growth Factor Binding Protein-3 by Senescent Human Fibroblasts: Attenuation of the Mitogenic Response to IGF-I

Experimental Cell Research ◽

10.1006/excr.1995.1234 ◽

1995 ◽

Vol 219 (2) ◽

pp. 315-321 ◽

Author(s):

Vitalii G. Grigoriev ◽

Elena J. Moerman ◽

Samuel Goldstein

Keyword(s):

Growth Factor ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

Mitogenic Response ◽

Factor Binding ◽

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Porcine Aortic Smooth Muscle Cells Secrete a Serine Protease for Insulin-like Growth Factor Binding Protein-2

Circulation Research ◽

10.1161/01.res.76.4.514 ◽

1995 ◽

Vol 76 (4) ◽

pp. 514-521 ◽

Author(s):

Amy Gockerman ◽

David R. Clemmons

Keyword(s):

Smooth Muscle ◽

Growth Factor ◽

Smooth Muscle Cells ◽

Serine Protease ◽

Binding Protein ◽

Muscle Cells ◽

Insulin Like Growth Factor ◽

Aortic Smooth Muscle Cells ◽

Aortic Smooth Muscle ◽

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Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of senescent and quiescent human fibroblasts.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.21.9680 ◽

1991 ◽

Vol 88 (21) ◽

pp. 9680-9684 ◽

Author(s):

S. Goldstein ◽

E. J. Moerman ◽

R. A. Jones ◽

R. C. Baxter

Keyword(s):

Growth Factor ◽

Culture Medium ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

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Insulin-like growth factor binding protein-3 is overexpressed in senescent and quiescent human fibroblasts

Experimental Gerontology ◽

10.1016/0531-5565(93)90063-j ◽

1993 ◽

Vol 28 (4-5) ◽

pp. 361-370 ◽

Author(s):

Elena J. Moerman ◽

Ray Thweatt ◽

Andrea M. Moerman ◽

Richard A. Jones ◽

Samuel Goldstein

Keyword(s):

Growth Factor ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

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Accumulation of insulin-like growth factor binding protein-3 in conditioned medium of human fibroblasts increases with chronologic age of donor and senescence in vitro

Journal of Cellular Physiology ◽

10.1002/jcp.1041560211 ◽

1993 ◽

Vol 156 (2) ◽

pp. 294-302 ◽

Author(s):

Samuel Goldstein ◽

Elena J. Moerman ◽

Robert C. Baxter

Keyword(s):

Growth Factor ◽

Conditioned Medium ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

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Control of Insulin-Like Growth Factor Binding Protein-5 Protease Synthesis and Secretion by Human Fibroblasts and Porcine Aortic Smooth Muscle Cells

Endocrinology ◽

10.1210/en.2002-220896 ◽

2003 ◽

Vol 144 (6) ◽

pp. 2489-2495 ◽

Author(s):

Anna Moralez ◽

Walker H. Busby ◽

David Clemmons

Keyword(s):

Smooth Muscle ◽

Growth Factor ◽

Smooth Muscle Cells ◽

Binding Protein ◽

Human Fibroblasts ◽

Muscle Cells ◽

Insulin Like Growth Factor ◽

Aortic Smooth Muscle Cells ◽

Aortic Smooth Muscle ◽

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Characterization and determination of the relative abundance of two types of insulin-like growth factor binding protein-5 proteases that are secreted by human fibroblasts.

Endocrinology ◽

10.1210/endo.137.12.8940380 ◽

1996 ◽

Vol 137 (12) ◽

pp. 5530-5536 ◽

Author(s):

T J Nam ◽

W H Busby ◽

D R Clemmons

Keyword(s):

Growth Factor ◽

Relative Abundance ◽

Binding Protein ◽

Human Fibroblasts ◽

Insulin Like Growth Factor ◽

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Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts. Insulin-like growth factor dependence and biological studies.

Journal of Clinical Investigation ◽

10.1172/jci116272 ◽

1993 ◽

Vol 91 (3) ◽

pp. 1129-1137 ◽

Author(s):

C A Conover ◽

M C Kiefer ◽

J Zapf

Keyword(s):

Growth Factor ◽

Binding Protein ◽

Human Fibroblasts ◽

Posttranslational Regulation ◽

Insulin Like Growth Factor ◽

Factor Binding ◽

Biological Studies

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