scholarly journals Potential Role of Metal Chelation to Prevent the Cardiovascular Complications of Diabetes

2019 ◽  
Vol 104 (7) ◽  
pp. 2931-2941
Author(s):  
Rossana Calderon Moreno ◽  
Ana Navas-Acien ◽  
Esteban Escolar ◽  
David M Nathan ◽  
Jonathan Newman ◽  
...  
Keyword(s):  
Potential Role ◽  
Cardiovascular Complications ◽  
Metal Chelation ◽  
Complications Of Diabetes

scholarly journals Self-monitoring of blood glucose in patients with diabetes and cardiac pathology with the Meter Contour TS use

2014 ◽  
Vol 5 (3-4) ◽  
pp. 14-19
Author(s):  
I. I Kochergina
Keyword(s):  
Blood Glucose ◽  
Early Detection ◽  
Cardiovascular Complications ◽  
Self Monitoring ◽  
Cardiac Pathology ◽  
Complications Of Diabetes ◽  
Acute Complications ◽  
Patients With Diabetes

The article presents data on the prevalence of diabetes, the role of hyper - and hypoglycemia in the development of cardiovascular complications, the importance of self-monitoring for early detection of acute complications of diabetes and compensation, as well as the use of Contour TS meter for this purpose.

scholarly journals Cardiorenal Syndrome in Acute Heart Failure Syndromes

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Mohammad Sarraf ◽  
Robert W. Schrier
Keyword(s):  
Heart Failure ◽  
Water Retention ◽  
Potential Role ◽  
Cardiorenal Syndrome ◽  
Cardiovascular Complications ◽  
Pharmacological Agents ◽  
Sequence Of Events ◽  
Acute Heart Failure Syndromes ◽  
Impaired Cardiac Function

Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome. This is different from the increase in cardiovascular complications which occur with primary kidney disease, that is, the so-called Renocardiac Syndrome. The present review discusses the pathogenesis of the Cardiorenal Syndrome followed by the benefits and potential deleterious effects of pharmacological agents that have been used in this setting. The agents discussed are diuretics, aquaretics, natriuretic peptides, vasodilators, inotropes and adenosineα1 receptor antagonists. The potential role of ultrafiltration is also briefly discussed.

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

The Effect of Path Length and Display Size on Memory for Spatial Information

2012 ◽  
Vol 59 (3) ◽  
pp. 147-152 ◽  
Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay
Keyword(s):  
Path Length ◽  
Potential Role ◽  
Spatial Information ◽  
Recall Performance ◽  
Minor Role ◽  
Length Effect ◽  
Serial Memory ◽  
Fixed Reference ◽  
A Minor

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.

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