scholarly journals Effects of Contraceptive Use on Bone Biochemical Markers in Young Women1

2001 ◽  
Vol 86 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Susan M. Ott ◽  
Delia Scholes ◽  
Andrea Z. LaCroix ◽  
Laura E. Ichikawa ◽  
Cathleen K. Yoshida ◽  
...  
2013 ◽  
Author(s):  
Swolin-Eide Diana ◽  
Braathen Gunnar ◽  
Emilsson Roger ◽  
Glansen Ulla ◽  
Soderpalm Ann-Charlott ◽  
...  

2011 ◽  
Vol 33 (4) ◽  
pp. 171-177 ◽  
Author(s):  
Soha Eldessouki Ibrahim ◽  
Heba F. ElShishtawy ◽  
Amir Helmy ◽  
Zeinab A. Galal ◽  
Maha Hussein Abdel Salam

2004 ◽  
Vol 50 (6) ◽  
pp. 619-624 ◽  
Author(s):  
Masayoshi Yamaguchi ◽  
Aki Igarashi ◽  
Satoshi Uchiyama ◽  
Seiichi Morita ◽  
Kuniaki Sugawara ◽  
...  

2006 ◽  
Vol 24 (5) ◽  
pp. 380-385 ◽  
Author(s):  
Yin-Zhen Pi ◽  
Xian-Ping Wu ◽  
Shi-Ping Liu ◽  
Xiang-Hang Luo ◽  
Xing-Zhi Cao ◽  
...  

2021 ◽  
pp. bmjmilitary-2020-001745
Author(s):  
Charlotte V Coombs ◽  
T J O'Leary ◽  
J C Y Tang ◽  
W D Fraser ◽  
J P Greeves

IntroductionHormonal contraceptive use might impair bone health and increase the risk of stress fracture by decreasing endogenous oestrogen production, a central regulator of bone metabolism. This cross-sectional study investigated bone density and biochemical markers of bone metabolism in women taking hormonal contraceptives on entry to basic military training.MethodsForty-five female British Army recruits had biochemical markers of bone metabolism, areal bone mineral density (aBMD) and tibial speed of sound (tSOS) measured at the start of basic military training. Participants were compared by their method of hormonal contraception: no hormonal contraception (NONE), combined contraceptive pill (CP) or depot-medroxyprogesterone acetate (DMPA) (20±2.8 years, 1.64±0.63 m, 61.7±6.2 kg).ResultsaBMD was not different between groups (p≥0.204), but tSOS was higher in NONE (3%, p=0.014) when compared with DMPA users. Beta C-terminal telopeptide was higher in NONE (45%, p=0.037) and DMPA users (90%, p=0.003) compared with CP users. Procollagen type 1 N-terminal propeptide was higher in DMPA users compared with NONE (43%, p=0.045) and CP users (127%, p=0.001), and higher in NONE compared with CP users (59%, p=0.014). Bone alkaline phosphatase was higher in DMPA users compared with CP users (56%, p=0.044).ConclusionsDMPA use was associated with increased bone turnover and decreased cortical bone integrity of the tibia. Lower cortical bone integrity in DMPA users was possibly mediated by increased intracortical remodelling, but trabecular bone was not affected by contraceptive use.


Sign in / Sign up

Export Citation Format

Share Document