Insight into Structural Demand for Cold Crystallization of a Small Molecule. A Case Study for Schiff Base Compounds that Exhibit Prototropic Tautomerization

2018 ◽  
Vol 91 (4) ◽  
pp. 669-677 ◽  
Author(s):  
Katsunori Iwase ◽  
Yasuhiro Toyama ◽  
Isao Yoshikawa ◽  
Yasuhisa Yamamura ◽  
Kazuya Saito ◽  
...  
Keyword(s):  
Schiff Base ◽  
Small Molecule ◽  
Cold Crystallization ◽  
Structural Demand ◽  
Insight Into

scholarly journals Illustrated step by step protocol to perform molecular docking: Human estrogen receptor complex with 4-hydroxytamoxifen as a case study

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Shafi Ullah Khan ◽  
Nafees Ahemad ◽  
Lay-Hong Chuah ◽  
Rakesh Naidu ◽  
Thet Thet Htar
Keyword(s):  
Estrogen Receptor ◽  
Molecular Docking ◽  
Small Molecule ◽  
Receptor Complex ◽  
Structure Based Drug Design ◽  
Human Estrogen Receptor ◽  
Docking Calculations ◽  
Basic Insight ◽  
Insight Into

Molecular docking is one of the most frequently used technique in structure-based drug design. Molecular docking can predict the binding-conformation and interactions of small molecule to the appropriate binding site within the target protein. This tutorial aimed to design a step by step protocol to get the basic insight into the molecular docking calculations employing very simple and easy to follow procedure

Margins and Modernity: A Geocritical Approach to Anna Seward's Llangollen Vale

Romanticism ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 69-80
Author(s):  
Ruth Knezevich
Keyword(s):  
Analytic Approach ◽  
Romantic Era ◽  
Insight Into

The genre of annotated verse represents an under-explored form of transporting romanticism. In annotated, locodescriptive poems like those in Anna Seward's Llangollen Vale, readers are invited to read not only the spatiality of the landscapes depicted in the verse but also the landscape of the page itself. Seward's poems, with their focus on understanding geographical, political, and historical spaces both real and imaginary, provide geocritical insight into poetic productions of the early Romantic era. Likewise, geocriticism offers a fresh and useful – even necessary – analytic approach to such poems. I adopt Anna Seward as a case study in annotated verse and argue that attending to the materiality and paratextuality of her work allows us to access the complexities of her poetry and prose as well as her position within the wider framework of transporting Romanticism.

Transformative Encounters and Uncanny Intimacies: Biotechnology and Contemporary Art – A Practitioner's Approach and Perspective

Somatechnics ◽  
2012 ◽  
Vol 2 (2) ◽  
pp. 263-283 ◽  
Author(s):  
Svenja J. Kratz
Keyword(s):  
Tissue Culture ◽  
Human Skin ◽  
Contemporary Art ◽  
Skin Equivalent ◽  
Biomedical Innovation ◽  
Equivalent Models ◽  
Science Projects ◽  
Insight Into ◽  
Human Skin Equivalent

Abstract: Presented from an ArtScience practitioner's perspective, this paper provides an overview of Svenja Kratz's experience working as an artist within the area of cell and tissue culture at QUT's Institute of Health and Biomedical Innovation (IHBI). Using The Absence of Alice, a multi-medium exhibition based on the experience of culturing cells, as a case study, the paper gives insight into the artist's approach to working across art and science and how ideas, processes, and languages from each discipline can intermesh and extend the possibilities of each system. The paper also provides an overview of her most recent artwork, The Human Skin Equivalent/Experience Project, which involves the creation of personal jewellery items incorporating human skin equivalent models grown from the artist's skin and participant cells. Referencing this project, and other contemporary bioart works, the value of ArtScience is discussed, focusing in particular on the way in which cross-art-science projects enable an alternative voice to enter into scientific dialogues and have the potential to yield outcomes valuable to both disciplines.

A Novel Integrated Reliability Test System for BEOL TDDB Study

2012 ◽  
Author(s):  
Jifeng Chen ◽  
Peilin Song ◽  
Thomas M. Shaw ◽  
Franco Stellari ◽  
Lynne Gignac ◽  
...  
Keyword(s):  
Preliminary Analysis ◽  
Dielectric Breakdown ◽  
Test System ◽  
Accurate Information ◽  
Reliability Test ◽  
Electrical Measurements ◽  
Time Dependent Dielectric Breakdown ◽  
Microscopy Images ◽  
Insight Into

Abstract In this paper, we propose a new methodology and test system to enable the early detection and precise localization of Time-Dependent-Dielectric-Breakdown (TDDB) occurrence in Back-End-of-Line (BEOL) interconnection. The methodology is implemented as a novel Integrated Reliability Test System (IRTS). In particular, through our methodology and test system, we can easily synchronize electrical measurements and emission microscopy images to gather more accurate information and thereby gain insight into the nature of the defects and their relationship to chip manufacturing steps and materials, so that we can ultimately better engineer these steps for higher reliable systems. The details of our IRTS will be presented along with a case study and preliminary analysis results.

Radical Subject Acceleration for Gifted Students: One School's Response

2019 ◽  
pp. 29-46
Author(s):  
Kaye Chalwell ◽  
Therese Cumming
Keyword(s):  
Gifted And Talented ◽  
Gifted Students ◽  
Subject Area ◽  
Lessons Learned ◽  
Gifted Student ◽  
Learning Needs ◽  
Mathematically Gifted ◽  
Support Students ◽  
Insight Into

Radical subject acceleration, or moving students through a subject area faster than is typical, including skipping grades, is a widely accepted approach to support students who are gifted and talented. This is done in order to match the student’s cognitive level and learning needs. This case study explored radical subject acceleration for gifted students by focusing on one school’s response to the learning needs of a ten year old mathematically gifted student. It provides insight into the challenges, accommodations and approach to radical subject acceleration in an Australian school. It explored the processes and decisions made to ensure that a gifted student’s learning needs were met and identified salient issues for radical subject acceleration. Lessons learned from this case study may be helpful for schools considering radical acceleration.

Ethnic Enterprises, Class Resources and Market Conditions: Indian owned SMEs in Malaysia

2018 ◽  
Vol 35 (2) ◽  
pp. 5-29
Author(s):  
JESRINA ANN XAVIER ◽  
EDMUND TERENCE GOMEZ
Keyword(s):  
Food Industry ◽  
Case Study Method ◽  
Market Conditions ◽  
New Generation ◽  
Insight Into

This article investigates changes in the conduct of ethnic enterprises followingthe emergence of a new generation of owners with varying class resources andas market conditions transform. The case study method is used to examinethe impact of changing class resources and market conditions on ethnicallybasedenterprises, exploring the effects of generational transitions among smallIndian owned companies in the food industry in Malaysia. The results providean insight into key changes in the evolution of Indian owned enterprises. Theyindicate that changes in class resources and market conditions have enabledIndian owned food-based companies to alter their products to fit a largermarket, while responding to the demands of a rapidly modernizing society.

A NEW INSIGHT INTO THE TRANSPORT AND STORAGE OF MAGMA IN SUBVOLCANIC SYSTEMS: A CASE STUDY FROM THE REYDARA LACCOLITH, SE ICELAND

2019 ◽  
Author(s):  
Michael Petronis ◽  
◽  
Vincent Twomey ◽  
William McCarthy ◽  
Craig MaGee
Keyword(s):  
And Storage ◽  
Insight Into

Insight into the formation of H-bonds propagating the monomeric zinc complexes of a tridentate reduced Schiff base to form an infinite chain

CrystEngComm ◽  
2021 ◽  
Author(s):  
Mainak Karmakar ◽  
Antonio Frontera ◽  
Shouvik Chattopadhyay
Keyword(s):  
Schiff Base ◽  
Solid State ◽  
Dft Calculations ◽  
Zinc Complexes ◽  
Infinite Chain ◽  
State Structure ◽  
Computational Tools ◽  
Solid State Structure ◽  
Reduced Schiff Base ◽  
Insight Into

The formation of an infinite 1D assembly is governed by the H-bonding interactions in the solid state structure of the two zinc complexes. It has been analyzed energetically using DFT calculations and several computational tools.

scholarly journals Whose Landscape Is It? Remapping Memory and History in Interwar Central Europe

2021 ◽  
pp. 1-26
Author(s):  
Nóra Veszprémi
Keyword(s):  
Visual Culture ◽  
Interwar Period ◽  
Historical Memory ◽  
Political Agenda ◽  
Mental Maps ◽  
Habsburg Empire ◽  
Cultural Traditions ◽  
Place Memory ◽  
Insight Into

Abstract After the collapse of the Habsburg Empire and the sanctioning of new national borders in 1920, the successor states faced the controversial task of reconceptualizing the idea of national territory. Images of historically significant landscapes played a crucial role in this process. Employing the concept of mental maps, this article explores how such images shaped the connections between place, memory, and landscape in Hungary and Czechoslovakia. Hungarian revisionist publications demonstrate how Hungarian nationalists visualized the organic integrity of “Greater Hungary,” while also implicitly adapting historical memory to the new geopolitical situation. As a counterpoint, images of the Váh region produced in interwar Czechoslovakia reveal how an opposing political agenda gave rise to a different imagery, while drawing on shared cultural traditions from the imperial past. Finally, the case study of Dévény/Devín/Theben shows how the idea of being positioned “between East and West” lived on in overlapping but politically opposed mental maps in the interwar period. By examining the cracks and continuities in the picturesque landscape tradition after 1918, the article offers new insight into the similarities and differences of nation-building processes from the perspective of visual culture.

scholarly journals A Case Study of a Negotiated Tender within a Small-to-Medium Construction Contractor: Modelling Project Cost Variance

Buildings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 260
Author(s):  
James Ellis ◽  
David John Edwards ◽  
Wellington Didibhuku Thwala ◽  
Obuks Ejohwomu ◽  
Ernest Effah Ameyaw ◽  
...  
Keyword(s):  
Construction Industry ◽  
Study Data ◽  
Review Literature ◽  
Third Party ◽  
Open Book ◽  
Competitive Tendering ◽  
Construction Contractor ◽  
The Uk ◽  
Insight Into

This research explores the failure of competitively tendered projects in the UK construction industry to procure the most suited contractor(s) to conduct the works. Such work may have equal relevance for other developed nations globally. This research seeks to teach clients and their representatives that “lowest price” does not mean “best value”, by presenting a case study of a successfully negotiated tender undertaken by a small-to-medium enterprise (SME) contractor; SME studies are relatively scant in academic literature. By applying the “lessons learnt” principle, this study seeks to improve future practice through the development of a novel alternative procurement option (i.e., negotiation). A mixed philosophical stance combining interpretivism and pragmatism was used—interpretivism to critically review literature in order to form the basis of inductive research to discuss negotiation as a viable procurement route, and pragmatism to analyse perceptions of tendering and procurement. The methods used follow a three-stage waterfall process including: (1) literature review and pilot study; (2) quantitative analysis of case study data; and (3) qualitative data collection via a focus group. Our research underscores the need to advise clients and their representatives of the importance of understanding the scope of works allowed within a tender submission before discounting it based solely on price. In addition, we highlight the failings of competitive tendering, which results in increased costs and project duration once the works commence on site. These findings provide new contemporary insight into procurement and tendering in the construction industry, with emphasis on SME contractors, existing relationships, and open-book negotiation. This research illustrates the adverse effects of early cost estimates produced without first securing a true understanding of project buildability and programming. Our work concludes with a novel insight into an alternative procurement option that involves early SME contractor involvement in an open-book environment, without the need for a third-party cost control.

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