scholarly journals Inhibitory Effects of Morinda citrifolia Extract and Its Constituents on Melanogenesis in Murine B16 Melanoma Cells

2012 ◽  
Vol 35 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Megumi Masuda ◽  
Kimihisa Itoh ◽  
Kazuya Murata ◽  
Shunsuke Naruto ◽  
Akemi Uwaya ◽  
...  
2014 ◽  
Vol 9 (4) ◽  
pp. 1934578X1400900
Author(s):  
Prasit Sirwannalert ◽  
Ryusho Kariya ◽  
Ikuko Suzu ◽  
Seiji Okada

The purposes of this study were to investigate the inhibitory effects of Salacia reticulata Tul. root extract on cellular oxidants and melanogenesis in B16 melanoma cells. Cells treated with non-toxic doses of S. reticulata root extract were investigated for their effects on melanogenesis, cellular tyrosinase activity and cellular oxidant scavenging activity. The results indicated that S. reticulata extract inhibited melanin synthesis and tyrosinase activity in α-MSH-induced or UV-irradiated B16 melanoma cells in a dose dependent manner. Additionally, the extract also exhibited anti-cellular oxidants in UV-induced radical melanoma cells. Altogether, these results suggested that S. reticulata root extract has roles in suppression of melanogenesis and oxidant inhibition. S. reticulata root extract may be a potential source for the development of pharmaceutical products for treatment of skin hyperpigmentation disorders.


2012 ◽  
Vol 7 (8) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Enos Tangke Arung ◽  
Shoko Furuta ◽  
Kazuhiro Sugamoto ◽  
Kuniyoshi Shimizu ◽  
Hiroya Ishikawa ◽  
...  

In our effort to find new whitening agents, we evaluated the effects of representative chalcones [4-hydroxyderricin (1), xanthoangelol (2), xanthoangelol H (3), deoxyxanthoangelol H (4), and deoxydihydroxanthoangelol H (5)] contained in the stem of Angelica keiskei on tyrosinase and melanin formation in B16 melanoma cells. In addition, the antioxidant effects of these chalcones in ORAC and DPPH assays were also determined. Interestingly, all chalcones (1–5) inhibit melanin formation in B16 melanoma cells, with low cytotoxicity.


2017 ◽  
Vol 46 (3) ◽  
pp. 320-326 ◽  
Author(s):  
Bo Yeon Shin ◽  
Bo Ram Jung ◽  
Jong Gi Jung ◽  
Seung Sik Cho ◽  
Mi Ae Bang

2013 ◽  
Vol 23 (18) ◽  
pp. 5178-5181 ◽  
Author(s):  
Takahiro Matsumoto ◽  
Seikou Nakamura ◽  
Souichi Nakashima ◽  
Masayuki Yoshikawa ◽  
Katsuyoshi Fujimoto ◽  
...  

2011 ◽  
Vol 75 (12) ◽  
pp. 2278-2282 ◽  
Author(s):  
Sayaka YOSHIOKA ◽  
Takao TERASHITA ◽  
Hajime YOSHIZUMI ◽  
Norifumi SHIRASAKA

2018 ◽  
Vol 9 (2) ◽  
pp. 1058-1069 ◽  
Author(s):  
Li-Xia Wang ◽  
Jia Qian ◽  
Li-Nan Zhao ◽  
Shao-Hua Zhao

Volatile oil from ginger suppressed melanogenesis through its antioxidant properties and the inhibitory effects on tyrosinase activity and melanogensis-related proteins.


2008 ◽  
Vol 72 (4) ◽  
pp. 1107-1110 ◽  
Author(s):  
Kenji OHGUCHI ◽  
Minako KOIKE ◽  
Yoshihide SUWA ◽  
Seiichi KOSHIMIZU ◽  
Yuki MIZUTANI ◽  
...  

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