scholarly journals Sophoraside A, a new aromatic glycoside from the roots of Sophora japonica.

1987 ◽  
Vol 35 (4) ◽  
pp. 1637-1640 ◽  
Author(s):  
Yoshiaki Shirataki ◽  
Yayoi Tagaya ◽  
Ichiro Yokoe ◽  
Manki Komatsu
Keyword(s):  
Sophora Japonica ◽  
Aromatic Glycoside

Structure Identification and Evaluation of Chemical Components from the Flos Sophorae Immaturus for Inhibitory Effects against HepG2

2021 ◽  
Vol 19 (4) ◽  
pp. 452-457
Author(s):  
Zhaohui Xue ◽  
Weichen Song ◽  
Xin Gao ◽  
Wancong Yu ◽  
Xiaonan Hou ◽  
...  
Keyword(s):  
Standard Of Care ◽  
Scientific Basis ◽  
Added Value ◽  
Structure Identification ◽  
Chemical Components ◽  
Active Components ◽  
Sophora Japonica ◽  
Beneficial Effects ◽  
Cell Proliferation Inhibition ◽  
Inhibition Potency

Flos Sophorae Immaturus, dried buds of Sophora japonica, exhibits multiple pharmacologic activities including anti-inflammatory, antiaging, and antiallergy effects as well as adjunct to standard of care cancer therapy. However, active components responsible for beneficial effects in cancer are not known. In this study, Flos Sophorae Immaturus was obtained by ethanol extraction, and eight components were purified, identified, and tested for HepG2 cell proliferation inhibition potency. The compounds identified to be the most effective inhibitors were campherol > isorhamnetin > quercetin. These data provide theoretical and scientific basis for the further development, utilization, and the promotion of added value of Flos Sophorae Immaturus.

Sign in / Sign up

Export Citation Format

Share Document