Association Between Major Adverse Cardiovascular Events and the Ratio of Subcutaneous Fat Area to Visceral Fat Area in Patients Who Have Undergone Multidetector Row Computed Tomography

OBJECTIVE: Hepatic steatosis may occur in association with insulin resistance and obesity, two features commonly seen in Cushing's syndrome (CS). The aim of this report is to assess the prevalence of hepatic steatosis in patients with active CS using computed tomography (CT) and to identify any associations between hepatic steatosis, endocrine and biochemical variables and body fat distribution. PATIENTS AND MEASUREMENTS: We identified 50 patients with active CS in whom appropriate CT was available to allow measurement of liver and spleen attenuation. In 26 patients, abdominal fat measurements were also available. Serum markers of CS and liver function tests were recorded. RESULTS: Ten of 50 patients had a liver-to-spleen CT attenuation ratio (L/S) of less than 1, indicating hepatic steatosis. There was a significant negative correlation between both liver attenuation and L/S ratio with total abdominal fat area, visceral fat area, the percentage of visceral fat and the visceral to subcutaneous fat ratio; the strongest negative correlation was found between visceral fat area and L/S ratio (r=-0.638, P<0.001, n=26). L/S ratio positively correlated with alkaline phosphatase levels (r=+0.423, P=0.044, n=23) but with no other serum marker of CS activity or liver enzyme. CONCLUSIONS: We have demonstrated hepatic steatosis on CT in 20% of patients with active CS. The presence of hepatic steatosis was significantly correlated with total abdominal fat area and visceral fat area.

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Higher visceral fat area/subcutaneous fat area ratio measured by computed tomography is associated with recurrence and poor survival in patients with mid and low rectal cancers

International Journal of Colorectal Disease ◽

10.1007/s00384-018-3065-z ◽

2018 ◽

Vol 33 (9) ◽

pp. 1303-1307 ◽

Cited By ~ 6

Author(s):

Kang Hong Lee ◽

Bo-kyeong Kang ◽

Byung Kyu Ahn

Keyword(s):

Computed Tomography ◽

Visceral Fat ◽

Subcutaneous Fat ◽

Area Ratio ◽

Poor Survival ◽

Visceral Fat Area ◽

Rectal Cancers

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The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Journal of Obesity & Metabolic Syndrome ◽

10.7570/jomes.2019.28.3.186 ◽

2019 ◽

Vol 28 (3) ◽

pp. 186-193 ◽

Cited By ~ 2

Author(s):

SoHee Kwon ◽

A Lum Han

Keyword(s):

Computed Tomography ◽

Cardiovascular Risk ◽

Visceral Fat ◽

Lipid Accumulation ◽

Subcutaneous Fat ◽

Lipid Accumulation Product ◽

Visceral Fat Area

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Visceral Fat Area Evaluation by Computed Tomography Correlates with Visceral Fat Volume

Global Journal of Health Science ◽

10.5539/gjhs.v9n10p78 ◽

2017 ◽

Vol 9 (10) ◽

pp. 78

Author(s):

Masato Mizui ◽

Yuji Mizoguchi ◽

Yutaka Senda ◽

Masayuki Yokoi ◽

Takao Tashiro

Keyword(s):

Computed Tomography ◽

Visceral Fat ◽

Subcutaneous Fat ◽

Area Measurement ◽

Abdominal Circumference ◽

Ct Scans ◽

Visceral Fat Area ◽

Visceral Fat Accumulation ◽

Fat Volume ◽

Very High

In Japan, the measurement of abdominal circumference is commonly used in diagnosis of visceral fat accumulation. It is also recommended that visceral fat at the umbilical level be measured using CT scans. If CT is used to measure the visceral fat area, we do not have to consider the possibility of measurement error due to subcutaneous fat. However, it is unknown whether the visceral fat area measurement by CT reflects the visceral fat volume of the entire abdomen.We examined the correlation between the visceral fat area at the umbilical level and the visceral fat volume of the entire abdomen using CT images taken from the diaphragm to the pubic bone.The results showed that there was a very high correlation between the visceral fat area and the visceral fat volume. The correlation was not affected by gender differences, old age or whether visceral fat was accumulated or not.Therefore, we concluded that it is possible to estimate the visceral fat volume of the entire abdomen by measuring the visceral fat area at the umbilical level.

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Coronary Angiography with Multidetector row Computed Tomography: Part II - Clinical Aspects

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2005.51.4.409 ◽

2004 ◽

Vol 51 (4) ◽

pp. 409

Author(s):

Dong Hun Kim ◽

Sang Il Choi ◽

Kyung Won Lee ◽

Hyuk Jae Chang ◽

Woo Young Chung ◽

...

Keyword(s):

Computed Tomography ◽

Coronary Angiography ◽

Clinical Aspects ◽

Multidetector Row Computed Tomography ◽

Multidetector Row

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Coronary Angiography with Multidetector row Computed Tomography: Part I - Technical Aspects

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2005.51.4.401 ◽

2004 ◽

Vol 51 (4) ◽

pp. 401

Author(s):

Dong Hun Kim ◽

Sang Il Choi ◽

Kyung Won Lee ◽

Sung Kwon Kang ◽

Seong Hoon Choi ◽

...

Keyword(s):

Computed Tomography ◽

Coronary Angiography ◽

Multidetector Row Computed Tomography ◽

Technical Aspects ◽

Multidetector Row

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Faculty Opinions recommendation of Plain radiography does not add any clinically significant advantage to multidetector row computed tomography in diagnosing cervical spine injuries in blunt trauma patients.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1157915.617976 ◽

2009 ◽

Author(s):

Elfyn Thomas

Keyword(s):

Computed Tomography ◽

Cervical Spine ◽

Blunt Trauma ◽

Plain Radiography ◽

Multidetector Row Computed Tomography ◽

Trauma Patients ◽

Cervical Spine Injuries ◽

Multidetector Row ◽

Spine Injuries ◽

Clinically Significant

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Visceral fat obesity is the key risk factor for the development of reflux erosive esophagitis in 40–69-years subjects

Esophagus ◽

10.1007/s10388-021-00859-5 ◽

2021 ◽

Author(s):

Shinya Ohashi ◽

Takahisa Maruno ◽

Keita Fukuyama ◽

Osamu Kikuchi ◽

Tomohiko Sunami ◽

...

Keyword(s):

Risk Factor ◽

Visceral Fat ◽

Subcutaneous Fat ◽

Erosive Esophagitis ◽

Smoking History ◽

Related Factors ◽

Visceral Fat Area ◽

Daily Alcohol Intake ◽

Gastrointestinal Reflux ◽

Total Fat

Abstract Background Visceral fat obesity can be defined quantitatively by abdominal computed tomography, however, the usefulness of measuring visceral fat area to assess the etiology of gastrointestinal reflux disease has not been fully elucidated. Methods A total of 433 healthy subjects aged 40–69 years (234 men, 199 women) were included in the study. The relationship between obesity-related factors (total fat area, visceral fat area, subcutaneous fat area, waist circumference, and body mass index) and the incidence of reflux erosive esophagitis was investigated. Lifestyle factors and stomach conditions relevant to the onset of erosive esophagitis were also analyzed. Results The prevalence of reflux erosive esophagitis was 27.2% (118/433; 106 men, 12 women). Visceral fat area was higher in subjects with erosive esophagitis than in those without (116.6 cm2 vs. 64.9 cm2, respectively). The incidence of erosive esophagitis was higher in subjects with visceral fat obesity (visceral fat area ≥ 100 cm2) than in those without (61.2% vs. 12.8%, respectively). Visceral fat obesity had the highest odds ratio (OR) among obesity-related factors. Multivariate analysis showed that visceral fat area was associated with the incidence of erosive esophagitis (OR = 2.18), indicating that it is an independent risk factor for erosive esophagitis. In addition, daily alcohol intake (OR = 1.54), gastric atrophy open type (OR = 0.29), and never-smoking history (OR = 0.49) were also independently associated with the development of erosive esophagitis. Conclusions Visceral fat obesity is the key risk factor for the development of reflux erosive esophagitis in subjects aged 40–69 years.

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