Factors associated with viral load suppression in HIV-infected pregnant women in Rio de Janeiro, Brazil

2012 ◽  
Vol 23 (1) ◽  
pp. 44-47 ◽  
Author(s):  
E C Joao ◽  
M I Gouvêa ◽  
J A Menezes ◽  
L C Sidi ◽  
M L S Cruz ◽  
...  
Keyword(s):  
Viral Load ◽  
Pregnant Women ◽  
Rio De Janeiro ◽  
Viral Load Suppression ◽  
Factors Associated

scholarly journals Factors associated with time to achieve an undetectable HIV RNA viral load after start of antiretroviral treatment in HIV-1-infected pregnant women

2017 ◽  
Vol 3 (1) ◽  
pp. 34-39 ◽  
Author(s):  
W. Snippenburg ◽  
F.J.B. Nellen ◽  
C. Smit ◽  
A.M.J. Wensing ◽  
M.H. Godfried ◽  
...  
Keyword(s):  
Viral Load ◽  
Pregnant Women ◽  
Antiretroviral Treatment ◽  
Factors Associated ◽  
Hiv Rna ◽  
Hiv 1

Overview of Factors Associated with HIV Viral Load Suppression in Transgender Women

2020 ◽  
Author(s):  
Zil G Goldstein
Keyword(s):  
Viral Load ◽  
Transgender Women ◽  
Hiv Treatment ◽  
Viral Load Suppression ◽  
Hiv Viral Load ◽  
Treatment Cascade ◽  
Factors Associated ◽  
The World ◽  
Hiv Treatment Cascade ◽  
Almost All

Abstract Background Transgender women face a significantly higher HIV burden than their cisgender counterparts around the world with worse treatment outcomes in almost all categories. Content A mini-review of the available literature discussing HIV risk and factors associated with HIV viral load suppression in transgender women. Summary This review discusses the disparities transgender women face that contribute to both of these factors including race as well as social determinants of health and how they affect the HIV treatment cascade in this population.

scholarly journals Prevalência e fatores associados ao consumo de álcool em gestantes adultas de uma maternidade pública no Rio de Janeiro / Prevalence and factors associated with alcohol consumption in adult pregnant women in a public maternity in Rio de Janeiro

2021 ◽  
Vol 7 (9) ◽  
pp. 87986-88004
Author(s):  
Gabriela Fernandes Moraes Fonseca ◽  
Patricia de Carvalho Padilha ◽  
Mayara Silva Dos Santos ◽  
Thaissa Santana Vieira Lima ◽  
Cláudia Saunders
Keyword(s):  
Alcohol Consumption ◽  
Pregnant Women ◽  
Rio De Janeiro ◽  
Factors Associated

scholarly journals Factors associated with non-adherence to prescribed iron supplement use: a study with pregnant women in the city of Rio de Janeiro

2016 ◽  
Vol 16 (2) ◽  
pp. 189-199 ◽  
Author(s):  
Roberta Pereira Niquini ◽  
Sonia Duarte de Azevedo Bittencourt ◽  
Elisa Maria de Aquino Lacerda ◽  
Cláudia Saunders ◽  
Maria do Carmo Leal
Keyword(s):  
Pregnant Women ◽  
Rio De Janeiro ◽  
National Health System ◽  
Cross Sectional Study ◽  
Multiple Regression Model ◽  
Deficiency Anemia ◽  
Cross Sectional ◽  
Factors Associated ◽  
Supplement Use ◽  
Basic Care

Abstract Objectives: to identify factors associated with non-use of iron supplements (IS) by pregnant women attending National Health System (SUS) prenatal care in the Municipality of Rio de Janeiro. Methods: a cross-sectional study was conducted in 2007/2008 with a representative sample of pregnant women using SUS hospitals and basic care in the Municipality of Rio de Janeiro. The group that had gestational age of ≥ 20 weeks at the time of the interview and who had been prescribed IS (n=1407) was subjected to a Poisson multiple regression model to estimate the association between use and independent variables. Results: of the 1407 pregnant women, 65% reported use of IS. Younger age, black skin/race, larger number of births, not having received guidance on use of IS, not having tried to obtain IS at the SUS (with a stronger association between pregnant women with lower levels of education and lower household assets indicator - HAI) and not having been able to obtain them at the SUS (amongpregnant women with lower HAI) were significantly associated with non-use. Conclusions: the guidance of health professionals regarding use of IS and their regular availability may increase adherence to prescription among pregnant women and prevent iron deficiency anemia.

scholarly journals Prevalence of Nonsuppressed Viral Load and Associated Factors Among Adults Receiving Antiretroviral Therapy in Eswatini, Lesotho, Malawi, Zambia, and Zimbabwe (2015-2017): Results from Population-Based Nationally-Representative Surveys

2020 ◽  
Author(s):  
Andreas D Haas ◽  
Elizabeth Radin ◽  
Avi J Hakim ◽  
Andreas Jahn ◽  
Neena Philip ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Virologic Failure ◽  
Scale Up ◽  
Female Gender ◽  
Antiretroviral Drugs ◽  
People Living With Hiv ◽  
Second Line ◽  
Viral Load Suppression ◽  
Factors Associated

Introduction: The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a target of ≥90% of people living with HIV (PLHIV) receiving antiretroviral therapy (ART) to have viral load suppression (VLS). We examined factors associated with nonsuppressed viral Load (NVL). Methods: We included PLHIV receiving ART aged 15-59 years from Eswatini, Lesotho, Malawi, Zambia, and Zimbabwe. Blood samples from PLHIV were analyzed for HIV RNA and recent exposure to antiretroviral drugs (ARVs). Outcomes were NVL (viral load ≥1000 copies/mL), virologic failure (VF; ARVs present and viral load ≥1000 copies/mL), interrupted ART (ARVs absent and viral load ≥1000 copies/mL), and receiving second-line ART. We calculated odds ratios and incidence rate ratios for factors associated with NVL, VF, interrupted ART, and switching to second-line ART. Results: The prevalence of NVL was 11.2%: 8.2% experienced VF, and 3.0% interrupted ART. Younger age, male gender, less education, suboptimal adherence, receiving nevirapine, HIV non-disclosure, never having married, and residing in Zimbabwe, Lesotho, or Zambia were associated with higher odds of NVL. Among people with NVL, marriage, female gender, shorter ART duration, higher CD4 count, and alcohol use were associated with higher odds for interrupted ART and lower odds for VF. Many people with VF (44.8%) had CD4 counts <200 cells/μL, but few (0.31% per year) switched to second-line ART. Conclusions: Countries are approaching UNAIDS VLS targets for adults. Treatment support for people initiating ART with asymptomatic HIV infection, scale-up of viral load monitoring, and optimized ART regimens may further reduce NVL prevalence.

scholarly journals Detectable HIV-RNA Viral Load Among HIV-Infected Pregnant Women on Treatment in Northern Uganda

2020 ◽  
Vol 9 (2) ◽  
pp. 232-241
Author(s):  
Agnes Napyo ◽  
James K Tumwine ◽  
David Mukunya ◽  
Josephine Tumuhamye ◽  
Anna Agnes Ojok Arach ◽  
...  
Keyword(s):  
Viral Load ◽  
Global Health ◽  
Protease Inhibitor ◽  
Pregnant Women ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Northern Uganda ◽  
Detectable Viral Load ◽  
Factors Associated ◽  
National Implementation

Background / Objectives: Detectable HIV viral load among HIV-infected pregnant women remains a public health threat. We aimed to determine factors associated with detectable viral load among HIV-infected pregnant women in Lira, Northern Uganda. Methods: We conducted a cross-sectional survey among 420 HIV-infected pregnant women attending Lira Regional Referral Hospital using a structured questionnaire and combined it with viral load tests from Uganda National Health Laboratories. We conducted multivariable logistic regression while adjusting for confounders to determine the factors associated with detectable viral load and we report adjusted odds ratios and proportion of women with viral load less than 50 copies/ml and above 1000 copies, respectively. Results: The prevalence of detectable viral load (>50 copies/ml) was 30.7% (95%CI: 26.3% - 35.4%) and >1000 copies/ml was 8.1% (95% CI: 5.7% – 11.1%). Factors associated with detectable viral load were not belonging to the Lango ethnicity (adjusted odds ratio = 1.92, 95%CI: 1.05 – 3.90) and taking a second-line (protease inhibitor-based) regimen (adjusted odds ratio = 4.41, 95%CI: 1.13 – 17.22). Conclusions and Global Health Implications: HIV-infected pregnant women likely to have detectable viral load included those taking a protease inhibitor-based regimen and those who were not natives of Lira. We recommend intensified clinical and psychosocial monitoring for medication compliance among HIVinfected pregnant women that are likely to have a detectable viral load to significantly lower the risk of vertical transmission of HIV in Lira specifically those taking a protease inhibitor-based regimen and those who are non-natives to the study setting. Much as the third 90% of the global UNAIDS 90-90-90 target has been achieved, the national implementation of PMTCT guidelines should be tailored to its contextual needs. Key words: • HIV • Women • Pregnancy • Pregnant women • Viral load • Viral suppression • PMTCT • Antiretroviral therapy • Uganda   Copyright © 2020 Napyo et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited.

scholarly journals Determinants of viral load non-suppression among people living with HIV on antiretroviral therapy in Kumasi, Ghana

2021 ◽  
Vol 55 (2) ◽  
pp. 111-117
Author(s):  
David Ansah ◽  
Emmanuel Kumah ◽  
Vitalis Bawontuo ◽  
Peter Agyei-Baffour ◽  
Emmanuel K Afriyie
Keyword(s):  
Viral Load ◽  
Educational Level ◽  
Viral Suppression ◽  
Outcome Measure ◽  
People Living With Hiv ◽  
Viral Load Suppression ◽  
Cross Sectional ◽  
Factors Associated ◽  
Comorbidity Status ◽  
Living With Hiv

Objectives: To determine the rate and factors associated with viral load non-suppression among adults living with HIV/AIDS on active anti-retroviral therapy (ART).Design: A retrospective cross-sectional studySetting: Three ART clinics in Kumasi, GhanaParticipants: All HIV-infected adults who were ≥18 years and on active ART for 12 months and whose viral loadnhad been estimated were included.Main outcome measure: Unsuppressed viral load among patients on ARTResults: In all, 483 HIV patients were included in the study, with 369 (76.4%) achieving viral load suppression. Gender, educational level, comorbidity status, and duration on ART were independently associated with viral nonsuppression (p < 0.05).Conclusions: This study has revealed that the rate of viral suppression in the study area is lower than the UNAIDS 90% target. The findings have implications on designing new and stemming up implementation of existing interventions to improve the rate of viral suppression among patients in the study area. It is also necessary that more of such studies are replicated in other parts of the country to identify risk factors for virological failure among patients on ART.

scholarly journals Maternal deaths following nevirapine-based antiretroviral therapy

2012 ◽  
Vol 13 (4) ◽  
pp. 196
Author(s):  
E Bera ◽  
D Naidoo ◽  
M Williams
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Adverse Effects ◽  
Hypersensitivity Reaction ◽  
Pregnant Women ◽  
Plasma Viral Load ◽  
Viral Load Suppression ◽  
Maternal Deaths ◽  
Cutaneous Eruption ◽  
Hiv Exposed

We report 2 cases illustrating that it is too simplistic to link nevirapine (NVP) toxicity exclusively to individuals with immune preservation. Not enough is known about the mechanism of hepatotoxicity or cutaneous eruption to predict these events. This type of hypersensitivity reaction occurs rarely among HIV-exposed infants taking NVP prophylaxis or antiretroviral therapy (ART)-experienced adults with complete plasma viral load suppression. Conversely, HIV-uninfected adults and ART-naive pregnant women appear to be disproportionately affected by the adverse effects of NVP.

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