Overview of Factors Associated with HIV Viral Load Suppression in Transgender Women

2020 ◽  
Author(s):  
Zil G Goldstein
Keyword(s):  
Viral Load ◽  
Transgender Women ◽  
Hiv Treatment ◽  
Viral Load Suppression ◽  
Hiv Viral Load ◽  
Treatment Cascade ◽  
Factors Associated ◽  
The World ◽  
Hiv Treatment Cascade ◽  
Almost All

Abstract Background Transgender women face a significantly higher HIV burden than their cisgender counterparts around the world with worse treatment outcomes in almost all categories. Content A mini-review of the available literature discussing HIV risk and factors associated with HIV viral load suppression in transgender women. Summary This review discusses the disparities transgender women face that contribute to both of these factors including race as well as social determinants of health and how they affect the HIV treatment cascade in this population.

scholarly journals Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam

2016 ◽  
Vol 2 (2) ◽  
pp. 94-101 ◽  
Author(s):  
Suresh Rangarajan ◽  
Donn J. Colby ◽  
Le Truong Giang ◽  
Duc Duong Bui ◽  
Huu Hung Nguyen ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Viral Load Suppression ◽  
Hiv Viral Load ◽  
Factors Associated

scholarly journals The Shinyanga Patient: A Patient’s Journey through HIV Treatment Cascade in Rural Tanzania

2021 ◽  
Vol 18 (16) ◽  
pp. 8418
Author(s):  
Nwanneka E. Okere ◽  
Veryeh Sambu ◽  
Yudas Ndungile ◽  
Eric van Praag ◽  
Sabine Hermans ◽  
...  
Keyword(s):  
Control Program ◽  
Hiv Treatment ◽  
People Living With Hiv ◽  
Load Testing ◽  
Hiv Viral Load ◽  
Treatment Cascade ◽  
For Profit ◽  
Rural Tanzania ◽  
Hiv Test ◽  
Hiv Treatment Cascade

The 2016–2017 Tanzania HIV Impact Survey (THIS) reported the accomplishments towards the 90-90-90 global HIV targets at 61-94-87, affirming the need to focus on the first 90 (i.e., getting 90% of people living with HIV (PLHIV) tested). We conducted a patient-pathway analysis to understand the gap observed, by assessing the alignment between where PLHIV seek healthcare and where HIV services are available in the Shinyanga region, Tanzania. We used existing and publicly available data from the National AIDS Control program, national surveys, registries, and relevant national reports. Region-wide, the majority (n = 458/722, 64%) of THIS respondents accessed their last HIV test at public sector facilities. There were 65.9%, 45.1%, and 74.1% who could also access antiretroviral therapy (ART), CD4 testing, and HIV viral load testing at the location of their last HIV test, respectively. In 2019, the viral suppression rate estimated among PLHIV on ART in the Shinyanga region was 91.5%. PLHIV access HIV testing mostly in public health facilities; our research shows that synergies can be achieved to improve access to services further down the cascade in this sector. Furthermore, effective engagement with the private sector (not-for-profit and for-profit) will help to achieve the last mile toward ending the HIV epidemic.

HIV treatment cascade among transgender women in a San Francisco respondent driven sampling study

2014 ◽  
Vol 90 (5) ◽  
pp. 430-433 ◽  
Author(s):  
Glenn-Milo Santos ◽  
Erin C Wilson ◽  
Jenna Rapues ◽  
Oscar Macias ◽  
Tracey Packer ◽  
...  
Keyword(s):  
San Francisco ◽  
Transgender Women ◽  
Hiv Treatment ◽  
Respondent Driven Sampling ◽  
Treatment Cascade ◽  
Hiv Treatment Cascade

Transgender women and HIV-related health disparities: falling off the HIV treatment cascade

Sexual Health ◽  
2017 ◽  
Vol 14 (5) ◽  
pp. 469 ◽  
Author(s):  
Seth C. Kalichman ◽  
Dominica Hernandez ◽  
Stephanie Finneran ◽  
Devon Price ◽  
Redd Driver
Keyword(s):  
Social Support ◽  
Health Disparities ◽  
Transgender Women ◽  
Hiv Treatment ◽  
Treatment Cascade ◽  
Women Living With Hiv ◽  
Hiv Treatment Cascade ◽  
Hiv Viral Suppression ◽  
Hiv Continuum Of Care ◽  
Living With Hiv

Background Transgender women living with HIV infection experience poorer health outcomes across the HIV continuum of care. While disparities are well established, their underlying mechanisms are not well understood. This study examined the HIV continuum of care (also known as the HIV treatment cascade), including linkage and engagement in care and health status among transgender women and cisgender women and cisgender men living with HIV. Method: Case-control matching was applied to a cohort of 1101 people living with HIV; 70 transgender women living with HIV were matched on years since testing HIV positive with cisgender women and cisgender men. Participants provided measures indicative of the HIV treatment cascade that included linkage and engagement in care, receiving and adhering to antiretroviral therapy (ART), and HIV viral suppression. Common correlates of HIV-related health status: depression symptoms, HIV-related stress, alcohol and drug use, healthcare conspiracy beliefs, medical mistrust, emotional social support and tangible social support, were also assessed. Results: Transgender women were significantly less likely to receive ART, were less adherent to ART and had poorer HIV viral suppression than cisgender persons. Multivariable models demonstrated that health disparities were predicted by transgender women having poorer tangible social support over and above the other correlates of health outcomes. Conclusion: Tangible support is amenable by interventions such as building and strengthening supportive networks and paraprofessional services. Socially supportive interventions should be considered critical in efforts to decrease HIV health disparities among transgender women.

scholarly journals Engaging the ‘Missing Men’ in the HIV Treatment Cascade: Creating a Tailored Intervention to Improve Men’s Uptake of HIV Care Services in Rural South Africa: A Study Protocol

2021 ◽  
Vol 18 (7) ◽  
pp. 3709
Author(s):  
Oluwafemi Adeagbo ◽  
Kammila Naidoo
Keyword(s):  
South Africa ◽  
Health Outcomes ◽  
Hiv Treatment ◽  
Hiv Care ◽  
Treatment Cascade ◽  
Hiv Care Cascade ◽  
Care Services ◽  
The Social ◽  
Hiv Treatment Cascade ◽  
Male Specific

Men, especially young men, have been consistently missing from the HIV care cascade, leading to poor health outcomes in men and ongoing transmission of HIV in young women in South Africa. Although these men may not be missing for the same reasons across the cascade and may need different interventions, early work has shown similar trends in men’s low uptake of HIV care services and suggested that the social costs of testing and accessing care are extremely high for men, particularly in South Africa. Interventions and data collection have hitherto, by and large, focused on men in relation to HIV prevention in women and have not approached the problem through the male lens. Using the participatory method, the overall aim of this study is to improve health outcomes in men and women through formative work to co-create male-specific interventions in an HIV-hyper endemic setting in rural KwaZulu-Natal, South Africa.

scholarly journals Threefold Increases in Population HIV Viral Load Suppression Among Men and Young Adults — Bukoba Municipal Council, Tanzania, 2014–2017

2019 ◽  
Vol 68 (30) ◽  
pp. 658-663
Author(s):  
Duncan MacKellar ◽  
Claire Steiner ◽  
Oscar E. Rwabiyago ◽  
Haddi J. Cham ◽  
Sherri Pals ◽  
...  
Keyword(s):  
Young Adults ◽  
Viral Load ◽  
Viral Load Suppression ◽  
Hiv Viral Load ◽  
Municipal Council

scholarly journals HIV virologic response better with single-tablet once daily regimens compared to multiple-tablet daily regimens

2018 ◽  
Vol 6 ◽  
pp. 205031211881691 ◽  
Author(s):  
Shashi N Kapadia ◽  
Robert R Grant ◽  
Susan B German ◽  
Baljinder Singh ◽  
Amy L Davidow ◽  
...  
Keyword(s):  
Viral Load ◽  
Confidence Interval ◽  
Undetectable Viral Load ◽  
The United States ◽  
Virologic Response ◽  
Hiv Treatment ◽  
Viral Load Suppression ◽  
Relative Risks ◽  
Treatment Naïve ◽  
Virologic Control

Background: Single-tablet regimens are preferred prescription choices for HIV treatment, but there are limited outcomes data comparing single-tablet regimens to multiple-tablet regimens. Methods: We retrospectively assessed treatment-naïve patients at a single urban HIV clinic in the United States for viral load suppression at 6 and 12 months after initiating either single-tablet or multiple-tablet regimens. Multivariate regression was performed to obtain relative risks and adjust for potential confounders. Results: Of 218 patients, 47% were on single-tablet regimens and 53% on multiple-tablet regimens; 77% of single-tablet regimen patients had undetectable viral load at 6 months compared to 61% of multiple-tablet regimen patients (p = 0.012). At 12 months, 82% on single-tablet regimens and 66% on multiple-tablet regimens (p = 0.019) had undetectable viral load. Relative risk of any detectable viral load was 1.6 (95% confidence interval: 1.1–2.5) for patients on multiple-tablet regimens compared to single-tablet regimens at 6 months, and 2.2 (95% confidence interval: 1.2–4.0) at 12 months. Conclusion: Single-tablet regimens may provide better virologic control than multiple-tablet regimens in urban HIV-infected persons.

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