Rising mother-to-child HIV transmission in a resource-limited breastfeeding population

2010 ◽  
Vol 40 (2) ◽  
pp. 70-73 ◽  
Author(s):  
Felicity Zvanyadza Gumbo ◽  
Nyaradzai Edith Kurewa ◽  
Gwendoline Quintoline Kandawasvika ◽  
Kerina Duri ◽  
Munyaradzi Paul Mapingure ◽  
...  

The objective of this study was to determine mother to child HIV transmission rates at different time points in a breastfeeding cohort enrolled in a single dose nevirapine program in Harare, Zimbabwe. Between 2002–2004, 434 HIV-positive mothers and their infants were recruited and followed up from delivery to 15 months. Infant blood specimens were collected for HIV testing at these time points. The majority of the patients (78%) received single dose nevirapine. The overall HIV transmission rate was 21.8% (17.8–25.8). Receiving single dose nevirapine was protective against HIV vertical transmission although statistically insignificant (relative risk: 0.76; 95% CI: 0.49–1.19). Breastfeeding was not found to be associated with HIV vertical transmission ( P = 0.612). In this resource-limited setting, HIV transmission rates are high. Efforts to use more efficacious regimens to arrest HIV vertical transmission are required.

2009 ◽  
Vol 50 (2) ◽  
pp. 223-230 ◽  
Author(s):  
Thérèse Delvaux ◽  
Batya Elul ◽  
Felix Ndagije ◽  
Elevanie Munyana ◽  
Dominique Roberfroid ◽  
...  

AIDS ◽  
2006 ◽  
Vol 20 (9) ◽  
pp. 1281-1288 ◽  
Author(s):  
Roger L Shapiro ◽  
Ibou Thior ◽  
Peter B Gilbert ◽  
Shahin Lockman ◽  
Carolyn Wester ◽  
...  

2006 ◽  
Vol 41 (1) ◽  
pp. 114-118 ◽  
Author(s):  
Sandra Albrecht ◽  
Katherine Semrau ◽  
Prisca Kasonde ◽  
Moses Sinkala ◽  
Chipepo Kankasa ◽  
...  

AIDS ◽  
2006 ◽  
Vol 20 (7) ◽  
pp. 995-1002 ◽  
Author(s):  
Shayne Loubser ◽  
Peter Balfe ◽  
Gayle Sherman ◽  
Scott Hammer ◽  
Louise Kuhn ◽  
...  

Author(s):  
Elidiana De Araújo Rosa ◽  
Hilda Jussara Santos de Souza ◽  
Janize Carlos da Silva

A AIDS é uma doença que representa um dos maiores problemas de saúde da atualidade em virtude de seu caráter pandêmico e gravidade. O índice de casos de AIDS vem crescendo em mulheres, acarretando aumento de crianças infectadas por transmissão vertical: transmissão do vírus do HIV da mãe para o filho durante a gestação. O governo brasileiro vem se empenhando para reduzir as taxas de transmissão vertical, implantando o Projeto Nascer, baseado no protocolo 076. Este estudo tem como objetivo demonstrar a eficácia do protocolo de prevenção da transmissão vertical a gestantes HIV+, evidenciando a importância do papel do enfermeiro no ciclo gravídico puerperal. Trata-se de uma pesquisa exploratória, sistemática, realizada a partir de uma revisão bibliográfica. Conclui-se que o Projeto Nascer é eficaz, no entanto, enfrenta algumas dificuldades na implantação. O enfermeiro, como participante da equipe, tem um papel fundamental para adesão da gestante ao protocolo.Descritores: HIV, Transmissão Vertical, Aconselhamento, Enfermagem. Project was born: the nurse in the prevention of vertical transmission of HIVAbstractAIDS is a disease that represents one of the biggest health problems of today because of his character and pandemic severity. The rate of AIDS cases is increasing in women, causing an increase in children infected by vertical transmission: transmission of the HIV virus from mother to child during pregnancy. The Brazilian government has been striving to reduce vertical transmission rates, by deploying the Sunrise Project, based in Protocol 076. This study aims to demonstrate the effectiveness of the protocol for the prevention of vertical HIV+ pregnant women, highlighting the important role of nurses en the puerperal pregnancy. This is an exploratory and systematic, made from a literature review. We concluded that the Sunrise Project is effective, however, faces some difficulties in implementation. The nurse, as part of the team, has a key role in the pregnant woman's accession to the Protocol.Descriptors: HIV, Transmission, Counseling, Nursing. Proyecto nació: lo enfermero em la prevención de la transmisión vertical del HIVResumenSIDA es una enfermedad que representa uno de mayores problemas de salud de la actualidad,debido a su carácter pandemia y una elevada mortalidad. Índice de casos de SIDA está aumentando en mujeres, causando aumento en los niños infectados por transmisión vertical: la transmisión del virus VIH de madre a hijo durante el embarazo. Gobierno brasileño se ha esforzado por reducir tasas de transmisión vertical, mediante implementación del Proyecto Nascer, basado en Protocolo 076. Este estudio tiene objetivo demonstrar la eficacia del protocolo de prevención de transmisión vertical en mujeres embarazadas VIH+, destacando el importante papel de las enfermeros en puerperio. Este es un estudio exploratorio, sistemático y teórico, efectuado a partir de revisión bibliográfica. Se concluye que el Proyecto Nascer es eficaz, sin embargo, se enfrenta a algunas dificultades en la aplicación. Enfermera, como parte del equipo, tiene un papel clave en adhesión de la mujer embarazada al Protocolo.Descriptores: VIH, Transmisión Vertical, Consejería, Enfermería.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Ghad Benali ◽  
Tanusha Ramdin ◽  
Daynia Ballot

Abstract Objective The aim of this study was to explore the prevalence of congenital HIV infection of neonates at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) between 2015 and 2017, as well as compare the HIV PCR positive and HIV PCR negative neonates. Results A total number of 1443 HIV exposed neonates was examined for the study period out of a total of 5029 admissions (HIV exposure 28.6%) The study found that the rate of HIV transmission at birth was 2.52%. The majority of infants had low birth weight and were also born prematurely. These results show that, despite the introduction of the extended mother to child transmission programme, HIV transmission is high.


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