Brenner tumors

2021 ◽  
Author(s):  
Filipa de Sousa Costeira ◽  
Ana Félix ◽  
Teresa Margarida Cunha
Keyword(s):  
Differential Diagnosis ◽  
Ovarian Neoplasms ◽  
Fibrous Tissue ◽  
Ovarian Neoplasm ◽  
Imaging Features ◽  
The Past ◽  
Dense Fibrous Tissue ◽  
Brenner Tumor ◽  
Brenner Tumors ◽  
Asymptomatic Women

Brenner tumors are rare ovarian neoplasms composed of ovarian transition cells surrounded by dense fibrous tissue. Most of them are small tumors (<2 cm), detected incidentally in asymptomatic women. Its predominantly fibrous content results in relatively low signal on T2 weighted images, establishing differential diagnosis with ovarian fibroma and thecoma. Their imaging features are very similar, the differentiation is based on secondary characteristics, such as signs or symptoms of estrogen excess and the presence of a second ovarian neoplasm, which has been reported in up to 30% of patients with Brenner tumor. Although originally thought to be universally benign, there have been scattered reports in the past decades of borderline and malignant forms of Brenner tumors.

Transmission Electron Microscopy of the Brenner Tumor. Contribution to the Histopathogenesis

1975 ◽  
Vol 33 ◽  
pp. 380-381
Author(s):  
I.M. B accarini
Keyword(s):  
Fibrous Tissue ◽  
Uranyl Acetate ◽  
Fresh Tissue ◽  
Ovarian Cortex ◽  
Dense Fibrous Tissue ◽  
Brenner Tumor ◽  
Transmission Electron ◽  
Acetate Lead ◽  
Brenner Tumors ◽  
The Many

The histogenetic interpretation of the Brenner tumor remains obscure, despite the many contributions that attempts to explain their origin.Six human ovaries containing islands of Brenner tumors were studied by histologic procedures and by the electron microscope; special stains, PAS, Oil red 0, toluidin blue and Wilder reticulum were also used. Fresh tissue was fixed in 3% glutaraldehyde, embedded in Epon, stained with Uranyl-acetate, Lead citrate and viewed in RCA E.M. The islands of tumor were located in the cortex, in the stroma or in the deep medulla; they were classified in developing, well developed, and degenerated one, depending upon the comparison of the histologic findings with the ultrastructure of the cytoplasmic organelles. These islands were set in a dense fibrous tissue in the stroma. In one case, the tumor was in the periphery of an ovarian fibroma developed in the ovarian cortex.The ultrastructure of the cells were identical, except for the different degree of degeneration, noted in some cells.

scholarly journals A rare presentation of benign Brenner tumor of ovary: a case report

2018 ◽  
Vol 7 (7) ◽  
pp. 2971
Author(s):  
Sumathi Periasamy ◽  
Subha Sivagami Sengodan ◽  
Devipriya . ◽  
Anbarasi Pandian
Keyword(s):  
Abdominal Pain ◽  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Pelvic Mass ◽  
Ovarian Tumors ◽  
Pathological Examination ◽  
Rare Presentation ◽  
Brenner Tumor ◽  
Benign Nature ◽  
Brenner Tumors

Brenner tumors are rare ovarian tumors accounting for 2-3% of all ovarian neoplasms and about 2% of these tumors are borderline (proliferating) or malignant. These tumors are commonly seen in 4th-8th decades of life with a peak in late 40s and early 50s. Benign Brenner tumors are usually small, <2cm in diameter and often detected incidentally during surgery or on pathological examination. Authors report a case of a large, calcified benign Brenner tumor in a 55-year-old postmenopausal woman who presented with complaint of abdominal pain and mass in abdomen. Imaging revealed large complex solid cystic pelvic mass -peritoneal fibrosarcoma. She underwent laparotomy which revealed huge Brenner tumor weighing 9kg arising from left uterine cornual end extending up to epigastric region. Myomectomy and hysterectomy with bilateral salphingo oophorectomy, omentectomy done and the specimen was sent for histopathological and immunohistochemistry study which revealed benign Brenner tumor. Brenner tumors are rare ovarian neoplasms accounting for 2-3% of all ovarian tumors. Benign Brenner tumors are usually small and solid whereas borderline and malignant Brenner tumors are usually larger and cystic with solid areas. But it is possible to have a completely benign large Brenner tumor. Therefore, benign nature of the lesion should not be excluded even when the ovarian tumor is very large.

scholarly journals Radiographic Features of a Benign Mixed Brenner Tumor and Mucinous Cystadenoma: A Rarely Identified Ovarian Neoplasm on Imaging

2020 ◽  
Vol 10 ◽  
pp. 22
Author(s):  
Mitchell P. Wilson ◽  
Prayash Katlariwala ◽  
June Hwang ◽  
Gavin Low
Keyword(s):  
Mucinous Cystadenoma ◽  
Ovarian Neoplasm ◽  
Imaging Features ◽  
Radiographic Features ◽  
Brenner Tumor ◽  
Mucinous Cystadenomas

Imaging features of benign mixed Brenner tumor and mucinous cystadenomas are rarely reported. This report aims to describe the case of a benign mixed Brenner tumor and mucinous cystadenoma with a dominant Brenner tumor component and to review the typical imaging features of this ovarian neoplasm.

A Case of an Extraosseous Pretibial Ganglion Cyst

2019 ◽  
Vol 1 ◽  
pp. 114-116
Author(s):  
Catrin Wigley ◽  
Guy Morris ◽  
Scott Evans ◽  
Rajesh Botchu
Keyword(s):  
Differential Diagnosis ◽  
Ganglion Cyst ◽  
Imaging Features ◽  
Oncology Service ◽  
Orthopedic Oncology

Pretibial lesion can have a plethora of differential diagnosis. We report a case of extraosseous pretibial ganglion cyst which was referred to our orthopedic oncology service and described the imaging features.

Borderline Brenner Tumor of the Ovary Coexisting With an Ovarian Mucinous Cystadenoma With Focal Atypical Epithelial Proliferation: A Rare Case With Review of the Literature

2021 ◽  
pp. 106689692199945
Author(s):  
Christine J. Salibay ◽  
Valentina Zanfagnin ◽  
Heather Miller ◽  
Saloni Walia ◽  
Laurie L. Brunette ◽  
...  
Keyword(s):  
Mucinous Cystadenoma ◽  
Clinicopathological Characteristics ◽  
Clinicopathological Features ◽  
Review Of The Literature ◽  
Epithelial Proliferation ◽  
Unique Case ◽  
Mucinous Neoplasm ◽  
Brenner Tumor ◽  
Clinical Presentations ◽  
Brenner Tumors

Ovarian Brenner tumors, accounting for ∼5% of overall ovarian epithelial neoplasm, are often reported in association with mucinous neoplasm. Histogenetically, the two tumors are thought to arise from similar precursors. To date, fewer than 60 borderline Brenner tumors alone have been reported, and the concomitant presence of atypical proliferative components in Brenner and mucinous tumors is even rarer. Therefore, the clinicopathological characteristics and prognosis of patients with the borderline Brenner tumors alone or coexisting with mucinous neoplasm are extremely limited. Herein, we report a unique case of a 53-year-old woman with a unilateral ovarian borderline Brenner tumor associated with focal atypical mucinous epithelial proliferation and her clinical presentations. The clinicopathological features of the tumor are documented and the literature review along with the clinical molecular advances are summarized in this study.

scholarly journals Not all that glitters is COVID! Differential diagnosis of FDG-avid interstitial lung disease in low-prevalence regions

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Annalisa Papa ◽  
Chiara Pozzessere ◽  
Francesco Cicone ◽  
Fabiola Rizzuto ◽  
Giuseppe Lucio Cascini
Keyword(s):  
Differential Diagnosis ◽  
Interstitial Lung Diseases ◽  
Routine Activity ◽  
Imaging Features ◽  
Pet Ct ◽  
Oncologic Patients ◽  
The Many ◽  
Fdg Pet Ct ◽  
Low Prevalence ◽  
Similar Imaging

Abstract Coronavirus disease-19 (COVID-19) is only one of the many possible infectious and non-infectious diseases that may occur with similar imaging features in patients undergoing [18F]-fluorodeoxyglucose (18FDG) monitoring, particularly in the most fragile oncologic patients. We briefly summarise some key radiological elements of differential diagnosis of interstitial lung diseases which, in our opinion, could be extremely useful for physicians reporting 18FDG PET/CT scans, not only during the COVID-19 pandemic, but also for their normal routine activity.

scholarly journals Extraosseous Ewing’s Sarcoma: Pictorial Review of Imaging Findings, Differential Diagnosis, and Pathologic Correlation

2021 ◽  
Author(s):  
Alan Alexander ◽  
Kyle Hunter ◽  
Michael Rubin ◽  
Ambarish P. Bhat
Keyword(s):  
Differential Diagnosis ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Multimodality Imaging ◽  
Imaging Features ◽  
Older Children ◽  
Radiologic Findings ◽  
Pictorial Review ◽  
Malignant Mesenchymal Tumor ◽  
Extraosseous Ewing’S Sarcoma

AbstractExtraosseous Ewing’s sarcoma (EES), first described in 1969, is a malignant mesenchymal tumor just like its intraosseous counterpart. Although Ewing’s sarcomas are common bone tumors in young children, EESs are rarer and more commonly found in older children/adults, often carrying a poorer prognosis. We discuss the multimodality imaging features of EES and the differential diagnosis of an aggressive appearing mass in proximity to skeletal structures, with pathologic correlates. This review highlights the need to recognize the variability of radiologic findings in EES such as the presence of hemorrhage, rich vascularity, and cystic or necrotic regions and its imaging similarity to other neoplasms that are closely related pathologically.

scholarly journals Petrous apex cholesterol granuloma: pictorial review of radiological considerations in diagnosis and surgical histopathology

2013 ◽  
Vol 127 (4) ◽  
pp. 339-348 ◽  
Author(s):  
M Hoa ◽  
J W House ◽  
F H Linthicum ◽  
J L Go
Keyword(s):  
Differential Diagnosis ◽  
Surgical Management ◽  
Fibrous Tissue ◽  
Tissue Reaction ◽  
Petrous Apex ◽  
Cholesterol Granuloma ◽  
Surgical Drainage ◽  
Radiological Features ◽  
Pictorial Review ◽  
Appropriate Treatment

AbstractBackground:Petrous apex cholesterol granulomas are expansile, cystic lesions containing cholesterol crystals surrounded by foreign body giant cells, fibrous tissue reaction and chronic inflammation. Appropriate treatment relies on an accurate radiological diagnosis and an understanding of the distinguishing radiological features of relevant entities in the differential diagnosis of this condition.Methods:Firstly, this paper presents a pictorial review of the relevant radiological features of petrous apex cholesterol granuloma, and highlights unique features relevant to the differential diagnosis. Secondly, it reviews the histopathological and radiological findings associated with surgical drainage of these lesions.Results:Radiological features relevant to the differential diagnosis of petrous apex cholesterol granuloma are reviewed, together with radiological and histopathological features relevant to surgical management. Following surgical management, histopathological and radiological evidence demonstrates that the patency of the surgical drainage pathway is maintained.Conclusion:Accurate diagnosis of petrous apex cholesterol granuloma is essential in order to instigate appropriate treatment. Placement of a stent in the drainage pathway may help to maintain patency and decrease the likelihood of symptomatic recurrence.

The cardiac conduction system in Hurler syndrome: pathological features and clinical implications

1992 ◽  
Vol 2 (2) ◽  
pp. 196-199
Author(s):  
Louis Tsun-cheung Chow ◽  
Wing-Hing Chow
Keyword(s):  
Sinus Node ◽  
Fibrous Tissue ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
Clinical Implications ◽  
Hurler Syndrome ◽  
Pathological Features ◽  
Hydropic Degeneration ◽  
Dense Fibrous Tissue

SummaryWe studied the cardiac conduction system in a case of Hurler syndrome. There was dense fibrosis of the supporting matrix of the sinus node and accumulation of mucopolysaccharide in the nodal cells. The bundle branches showed prominent hydropic degeneration, being encased and punctuated by dense fibrous tissue. These changes in the conduction system may predispose to the development of arrhythmias, accounting for the sudden deaths in Hurler syndrome.

DIAGNOSIS OF OVARIAN CANCER AND ACUTE ENDOMETRITIS BY NETWORK MODELING OF CHANGES IN BLOOD FLOW IN THE PELVIC ARTERIES

2021 ◽  
pp. 88-93
Author(s):  
Виталий Вячеславович Аксёнов ◽  
Николай Михайлович Агарков ◽  
Александра Игоревна Сурнина
Keyword(s):  
Ovarian Cancer ◽  
Blood Flow ◽  
Differential Diagnosis ◽  
Network Modeling ◽  
Correct Diagnosis ◽  
Arterial Blood Flow ◽  
Diagnostic Significance ◽  
The Past ◽  
Arterial Blood ◽  
High Level

Заболеваемость раком яичников в России в последнее время остается на высоком уровне. В мире более ста тысяч женщин умирают вследствие протекания данного заболевания. За последнее десятилетие заболеваемость острым эндометритом также неуклонно возрастает. Острый эндометрит обладает полиморфизмом симптомов, лабораторных и ультразвуковых изменений и вследствие этого тяжело поддается диагностике и дифференциальной диагностике. В условиях стационара обследованы 100 пациенток с раком яичников II-III стадии и 90 пациенток с диагнозом острого эндометрита. Им выполнялось ультразвуковое исследование. Полученные результаты подвергались обработке и математико-статистическому анализу, включающему расчёт показателей дезинтеграции, сетевое моделирование, математическое ранжирование. Изучение ультразвуковых изменений кровотока в маточных и яичниковых сосудах и венах у 100 заболевших раком яичников и 90 заболевших острым эндометритом дал возможность выделить ведущие дифференциально-диагностические аспекты. Характеристики дезинтеграции, в одном ряду со средними значениями локального кровотока, объективизируют дифференциацию рака яичников и острого эндометрита. В согласовании с дифференциально-диагностической значимостью ультразвуковых характеристик артериального кровотока в маточных и яичниковых сосудах построена сетевая модель дифференциальной диагностики рака яичников и острого эндометрита по более приоритетным переменам, собственно, что разрешает уменьшить размер и время обследования пациента и постановки верного диагноза The incidence of ovarian cancer in Russia has recently remained at a high level. In the world, more than a hundred thousand women die as a result of the course of this disease. The incidence of acute endometritis has also been steadily increasing over the past decade. Acute endometritis has a polymorphism of symptoms, laboratory and ultrasound changes and, as a result, is difficult to diagnose and differential diagnosis. 100 patients with stage II-III ovarian cancer and 90 patients with acute endometritis were examined in the hospital. They performed an ultrasound examination. The obtained results were processed and subjected to mathematical and statistical analysis, including the calculation of disintegration indicators, network modeling, and mathematical ranking. The study of ultrasound changes in blood flow in the uterine and ovarian vessels and veins in 100 patients with ovarian cancer and 90 patients with acute endometritis made it possible to identify the leading differential diagnostic aspects. The characteristics of disintegration, along with the average values of local blood flow, objectify the differentiation of ovarian cancer and acute endometritis. In accordance with the differential diagnostic significance of the ultrasound characteristics of arterial blood flow in the uterine and ovarian vessels, a network model for the differential diagnosis of ovarian cancer and acute endometritis is constructed according to higher priority changes, which actually allows reducing the size and time of the patient's examination and making the correct diagnosis

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