scholarly journals Septic Shock and Purpura Fulminans Due to Streptococcus pneumoniae Bacteremia in an Unvaccinated Immunocompetent Adult: Case Report and Review

2020 ◽  
Vol 21 ◽  
Author(s):  
Nikola Djurdjevic ◽  
Pahnwat Tonya Taweesedt ◽  
Margaret Paulson ◽  
Abigail LaNou ◽  
Milan Radovanovic ◽  
...  
Keyword(s):  
Septic Shock ◽  
Case Report ◽  
Streptococcus Pneumoniae ◽  
Purpura Fulminans ◽  
Adult Case ◽  
Immunocompetent Adult

scholarly journals Streptococcus pneumoniae–induced purpura fulminans in a woman with functional asplenia

CJEM ◽  
2014 ◽  
Vol 16 (04) ◽  
pp. 339-342 ◽  
Author(s):  
Jeremy M. Wojtowicz ◽  
Graham Longden Jones
Keyword(s):  
Septic Shock ◽  
Streptococcus Pneumoniae ◽  
Early Diagnosis ◽  
Clinical Presentation ◽  
Rare Complication ◽  
Purpura Fulminans ◽  
Rare Condition ◽  
Emergency Physicians ◽  
Aggressive Management ◽  
Increased Risk

ABSTRACTPurpura fulminans is a rare complication of septic shock, often associated withStreptococcus pneumoniae. Patients with anatomic or functional asplenia are at increased risk for infection because of impairment of their ability to defend against encapsulated pathogens. We report the case of a previously healthy, unimmunized 33-year-old female with functional asplenia who presented in septic shock and purpura fulminans and died in spite of maximal resuscitative measures. The clinical presentation, diagnosis, and management of purpura fulminans are reviewed. Purpura fulminans is a rare condition that requires early diagnosis and aggressive management by emergency physicians.

scholarly journals Purpura fulminans manifesting with Staphylococcus aureus endocarditis: a case report

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Anirudh Kumar ◽  
Nishant P Shah ◽  
Venu Menon ◽  
Steven E Nissen
Keyword(s):  
Staphylococcus Aureus ◽  
Septic Shock ◽  
Case Report ◽  
Protein C ◽  
Purpura Fulminans ◽  
Serum Levels ◽  
Protein C Concentrate ◽  
Staphylococcus Aureus Endocarditis ◽  
Diagnostic Work ◽  
Severe Septic Shock

AbstractBackgroundPurpura fulminans (PF) is a haematologic emergency that can occur in the setting of severe septic shock. Its pathophysiology is not well-understood; however, some evidence suggests it may be mediated by excessive protein C consumption.Case summaryIn this case report, we describe a patient with PF secondary to methicillin-resistant Staphylococcus aureus endocarditis. She presented with severe septic shock and, despite haemodynamic improvement, developed a significant purpuric rash. Diagnostic work-up was notable for severely decreased serum levels of protein C. This patient was successfully treated with protein C concentrate and surgical valve replacement.DiscussionWhile PF is rarely associated with S. aureus infection, this presentation may be more frequently encountered among clinicians in the current opioid epidemic. Quick recognition is crucial and a multidisciplinary approach, including intravenous infusion of protein C, may be considered.

scholarly journals Primary Leptomeningeal B-cell Lymphoma in an Immunocompetent Adult: Case Report

Cureus ◽  
2021 ◽  
Author(s):  
Andrea Calderon-Castro ◽  
Leonardo Enciso ◽  
Rafael Tejada-Cabrera
Keyword(s):  
Case Report ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Adult Case ◽  
Immunocompetent Adult
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