scholarly journals A neonate with hand, foot, and mouth disease complicated with brainstem encephalitis and pulmonary edema: A complete recovery

2014 ◽  
Vol 30 (4) ◽  
Author(s):  
Shi-Jie Guo ◽  
Dong-Xuan Wang ◽  
Chun-Lai Dai ◽  
Hui Wu
Keyword(s):  
Pulmonary Edema ◽  
Foot And Mouth Disease ◽  
Complete Recovery ◽  
Mouth Disease ◽  
Brainstem Encephalitis ◽  
Foot And Mouth

scholarly journals Irregular Poliovirus Vaccination Correlates to Pulmonary Edema of Hand, Foot, and Mouth Disease

2011 ◽  
Vol 18 (9) ◽  
pp. 1589-1590 ◽  
Author(s):  
Chaoyang Deng ◽  
Chunfu Yang ◽  
Junfeng Wan ◽  
Liye Zhu ◽  
Qibin Leng
Keyword(s):  
Pulmonary Edema ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Foot And Mouth

scholarly journals Interleukin-8 is elevated in severe hand, foot, and mouth disease

2014 ◽  
Vol 8 (01) ◽  
pp. 094-100 ◽  
Author(s):  
Wen Wang ◽  
Wei Li ◽  
Xue Yang ◽  
Tong Zhang ◽  
Yuxuan Wang ◽  
...  
Keyword(s):  
Disease Severity ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Length Of Hospital Stay ◽  
Mouth Disease ◽  
Brainstem Encephalitis ◽  
Laboratory Findings ◽  
Serum Cytokines ◽  
Foot And Mouth ◽  
Isolated Brainstem

Introduction: Enterovirus 71 (EV71) infections can cause hand, foot, and mouth disease (HFMD), which is a potentially fatal illness in children. Epidemics of HFMD are seen every year globally and present an increasing threat to public health worldwide. Methodology: To identify potential severity markers for severe HFMD, laboratory findings and levels of eight serum cytokines in 143 EV71-infected patients in Beijing You’an Hospital were analyzed. Patients were grouped by disease severity: Mild (no severe complications) (n = 59), isolated isolated brainstem encephalitis (BE) (n = 47), isolated pulmonary edema (PE) (n = 12), and BE+PE (n = 25). Results: IL-8 levels peaked at day one after admission and were found to be correlated to disease severity, maximal body temperature, and length of hospital stay. Among all tested cytokines, IL-8 was correlated to only IL-6 (p = 0.010). IL-6 and IL-10 were elevated in most patients (98.6% and 70.6%), but not correlated to disease severity (both p > 0.05). IFNg was only negatively correlated to mild cases (p = 0.025). Conclusions: IL-8 was correlated to disease severity of HFMD. IL-6 and IL-10, although elevated in most HFMD patients, were not correlated to disease severity.

scholarly journals Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema

2017 ◽  
Vol 13 (4) ◽  
pp. 1403-1407 ◽  
Author(s):  
Zhixin Yan ◽  
Yaokai Shang ◽  
Fengxian Li ◽  
Fei Xie ◽  
Huili Qian ◽  
...  
Keyword(s):  
Pulmonary Edema ◽  
Therapeutic Efficacy ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Foot And Mouth

Biophysical Measurement of Molecular Weight of Foot-and-Mouth Disease RNA Fragments

1974 ◽  
Vol 32 ◽  
pp. 262-263
Author(s):  
Sydney S. Breese ◽  
Howard L. Bachrach
Keyword(s):  
Chemical Properties ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Distilled Water ◽  
Bovine Plasma ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Carbon Coated ◽  
Rna Fragments ◽  
Physical And Chemical

Continuing studies on the physical and chemical properties of foot-and-mouth disease virus (FMDV) have included electron microscopy of RNA strands released when highly purified virus (1) was dialyzed against demlneralized distilled water. The RNA strands were dried on formvar-carbon coated electron microscope screens pretreated with 0.1% bovine plasma albumin in distilled water. At this low salt concentration the RNA strands were extended and were stained with 1% phosphotungstic acid. Random dispersions of strands were recorded on electron micrographs, enlarged to 30,000 or 40,000 X and the lengths measured with a map-measuring wheel. Figure 1 is a typical micrograph and Fig. 2 shows the distributions of strand lengths for the three major types of FMDV (A119 of 6/9/72; C3-Rezende of 1/5/73; and O1-Brugge of 8/24/73.

High resolution surface structure of foot-and-mouth disease virus

1978 ◽  
Vol 36 (2) ◽  
pp. 376-377
Author(s):  
S. S. Breese ◽  
H. L. Bachrach
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Surface Structure ◽  
Disease Virus ◽  
Potassium Phosphate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Physical Measurements ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.

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