scholarly journals Introducing high school students to the Gene Ontology classification system

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 241
Author(s):  
Mehek Dedhia ◽  
Kenneth Kohetuk ◽  
Wim E. Crusio ◽  
Anna Delprato

We present a tutorial that introduces high school students to the Gene Ontology classification system which is widely used in genomics and systems biology studies to characterize large sets of genes based on functional and structural information. This classification system is a valuable and standardized method used to identify genes that act in similar processes and pathways and also provides insight into the overall architecture and distribution of genes and gene families associated with a particular tissue or disease. By means of this tutorial, students learn how the classification system works through analyzing a gene set using DAVID the Database for Annotation, Visualization and Integrated Discovery that incorporates the Gene Ontology system into its suite of analysis tools. This method of profiling genes is used by our high school student interns to categorize gene expression data related to behavioral neuroscience. Students will get a feel for working with genes and gene sets, acquire vocabulary, obtain an understanding of how a database is structured and gain an awareness of the vast amount of information that is known about genes as well as the online analysis tools to manage this information that is nowadays available. Based on survey responses, students intellectually benefit from learning about the Gene Ontology System and using the DAVID tools, they are better prepared for future database use and they also find it enjoyable.

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 241
Author(s):  
Mehek Dedhia ◽  
Kenneth Kohetuk ◽  
Wim E. Crusio ◽  
Anna Delprato

We present a tutorial that introduces high school students to the Gene Ontology classification system which is widely used in genomics and systems biology studies to characterize large sets of genes based on functional and structural information. This classification system is a valuable and standardized method used to identify genes that act in similar processes and pathways and also provides insight into the overall architecture and distribution of genes and gene families associated with a particular tissue or disease. By means of this tutorial, students learn how the classification system works through analyzing a gene set using DAVID the Database for Annotation, Visualization and Integrated Discovery that incorporates the Gene Ontology system into its suite of analysis tools. This method of analyzing genes is used by our high school student interns to categorize gene expression data related to behavioral neuroscience. Students will get a feel for working with genes and gene sets, acquire vocabulary, obtain an understanding of how a database is structured and gain an awareness of the vast amount of information that is known about genes as well as the online analysis tools to manage this information that is nowadays available. Based on survey responses, students intellectually benefit from learning about the Gene Ontology System and using the DAVID tools, they are better prepared for future database use and they also find it enjoyable.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 241
Author(s):  
Mehek Dedhia ◽  
Kenneth Kohetuk ◽  
Wim E. Crusio ◽  
Anna Delprato

We present an activity that introduces high school students to the Gene Ontology classification system which is widely used in genomics and systems biology studies to characterize large sets of genes based on functional and structural information. This is a valuable and standardized method used to identify genes that act in similar processes and pathways and also to gain insight into the overall architecture and distribution of genes and gene families associated with a particular tissue or disease. Through this exercise, students will learn how the classification system works by analyzing a list of genes using DAVID the Database for Annotation, Visualization and Integrated Discovery that incorporates the Gene Ontology system into its suite of analysis tools. This method of profiling genes is used by our high school student interns to categorize gene expression data related to behavioral neuroscience. Students will get a feel for working with genes and gene sets, gain vocabulary, obtain an understanding of how a database is structured and gain an awareness of the vast amount of information that is known about genes as well as the online analysis tools that are available.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 241 ◽  
Author(s):  
Mehek Dedhia ◽  
Kenneth Kohetuk ◽  
Wim E. Crusio ◽  
Anna Delprato

We present a tutorial that introduces high school students to the Gene Ontology classification system which is widely used in genomics and systems biology studies to characterize large sets of genes based on functional and structural information. This classification system is a valuable and standardized method used to identify genes that act in similar processes and pathways and also provides insight into the overall architecture and distribution of genes and gene families associated with a particular tissue or disease. By means of this tutorial, students learn how the classification system works through analyzing a gene set using DAVID the Database for Annotation, Visualization and Integrated Discovery that incorporates the Gene Ontology system into its suite of analysis tools. This method of profiling genes is used by our high school student interns to categorize gene expression data related to behavioral neuroscience. Students will get a feel for working with genes and gene sets, acquire vocabulary, obtain an understanding of how a database is structured and gain an awareness of the vast amount of information that is known about genes as well as the online analysis tools to manage this information that is nowadays available. Based on survey responses, students intellectually benefit from learning about the Gene Ontology System and using the DAVID tools, they are better prepared for future database use and they also find it enjoyable.


1979 ◽  
Vol 10 (3) ◽  
pp. 139-144
Author(s):  
Cheri L. Florance ◽  
Judith O’Keefe

A modification of the Paired-Stimuli Parent Program (Florance, 1977) was adapted for the treatment of articulatory errors of visually handicapped children. Blind high school students served as clinical aides. A discussion of treatment methodology, and the results of administrating the program to 32 children, including a two-year follow-up evaluation to measure permanence of behavior change, is presented.


1999 ◽  
Vol 15 (1) ◽  
pp. 3-13 ◽  
Author(s):  
Robert J. Sternberg ◽  
Elena L. Grigorenko ◽  
Michel Ferrari ◽  
Pamela Clinkenbeard

Summary: This article describes a triarchic analysis of an aptitude-treatment interaction in a college-level introductory-psychology course given to selected high-school students. Of the 326 total participants, 199 were selected to be high in analytical, creative, or practical abilities, or in all three abilities, or in none of the three abilities. The selected students were placed in a course that either well matched or did not match their pattern of analytical, creative, and practical abilities. All students were assessed for memory, analytical, creative, and practical achievement. The data showed an aptitude-treatment interaction between students' varied ability patterns and the match or mismatch of these abilities to the different instructional groups.


2006 ◽  
Vol 11 (4) ◽  
pp. 268-276 ◽  
Author(s):  
Aida Orgocka ◽  
Jasna Jovanovic

This study examined how social opportunity structure influences identity exploration and commitment of Albanian high school students. A total of 258 students completed a questionnaire that gauged their identity exploration and commitment in three domains: education, occupation, and family. ANOVA results indicated that, overall, students scored highest in exploration in the domain of education and in commitment in the domain of family. Students' exploration and commitment were linked to gender. Albanian female students scored higher than male students in exploration and commitment regarding education and family. Perceived work opportunities in Albania or abroad also significantly moderated participants' exploration in the domain of education and were associated with commitment in education and occupation. As one of the first studies to explore Albanian youth's identity development in relation to social opportunity structure, findings are discussed in light of furthering the field of Albanian adolescent and youth development.


2016 ◽  
Vol 28 (3) ◽  
pp. 123-135 ◽  
Author(s):  
Raffael Heiss ◽  
Jörg Matthes

Abstract. This study investigated the effects of politicians’ nonparticipatory and participatory Facebook posts on young people’s political efficacy – a key determinant of political participation. We employed an experimental design, using a sample of N = 125 high school students (15–20 years). Participants either saw a Facebook profile with no posts (control condition), nonparticipatory posts, or participatory posts. While nonparticipatory posts did not affect participants’ political efficacy, participatory posts exerted distinct effects. For those high in trait evaluations of the politician presented in the stimulus material or low in political cynicism, we found significant positive effects on external and collective efficacy. By contrast, for those low in trait evaluations or high in cynicism, we found significant negative effects on external and collective efficacy. We did not find any effects on internal efficacy. The importance of content-specific factors and individual predispositions in assessing the influence of social media use on participation is discussed.


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