scholarly journals Case Report: Kikuchi-Fujimoto Disease: A case of supraclavicular lymphadenopathy

F1000Research ◽  
2021 ◽  
Vol 8 ◽  
pp. 1652
Author(s):  
Shiza Sarfraz ◽  
Hamza Rafique ◽  
Hassam Ali ◽  
Syed Zawahir Hassan
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Lymph Nodes ◽  
Cervical Lymphadenopathy ◽  
Tuberculous Lymphadenitis ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Supraclavicular Lymph Nodes ◽  
Necrotizing Lymphadenitis

Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare cause of cervical lymphadenopathy. Patients usually present with localized lymphadenopathy, fever and fatigue. Because of the poorly understood etiology, it can be mistaken for an infectious disease or even malignance. Here we discuss a case of KFD that initially presented with left sided cervical lymphadenopathy that later progressed to left supraclavicular lymph nodes. Due to its characteristic overlap with other disorders like tuberculous lymphadenitis and lymphoma, KFD remains an arduous diagnosis for physicians. Therefore, one should be made aware of symptoms that can lead to misdiagnosis in patients.

scholarly journals Case Report: Kikuchi-Fujimoto Disease: A case of supraclavicular lymphadenopathy

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1652
Author(s):  
Shiza Sarfraz ◽  
Hamza Rafique ◽  
Hassam Ali ◽  
Syed Zawahir Hassan
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Lymph Nodes ◽  
Cervical Lymphadenopathy ◽  
Tuberculous Lymphadenitis ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Supraclavicular Lymph Nodes ◽  
Necrotizing Lymphadenitis

Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare cause of cervical lymphadenopathy. Patients usually present with localized lymphadenopathy, fever and fatigue. Because of the poorly understood etiology, it can be mistaken for an infectious disease or even malignance. Here we discuss a case of KFD that initially presented with left sided cervical lymphadenopathy that later progressed to left supraclavicular lymph nodes. Due to its characteristic overlap with other disorders like tuberculous lymphadenitis and lymphoma, KFD remains an arduous diagnosis for physicians. Therefore, one should be made aware of symptoms that can lead to misdiagnosis in patients.

Histiocytic Necrotizing Lymphadenitis With Autoimmune Phenomena and Meningitis in a 14-Year-Old Girl

PEDIATRICS ◽  
1996 ◽  
Vol 98 (1) ◽  
pp. 130-133 ◽  
Author(s):  
Jason S. Debley ◽  
David J. Rozansky ◽  
Michael L. Miller ◽  
Ben Z. Katz ◽  
Marianne E. Greene
Keyword(s):  
United States ◽  
Weight Loss ◽  
Lymph Nodes ◽  
Cervical Lymphadenopathy ◽  
The United States ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Common Presentation ◽  
Necrotizing Lymphadenitis ◽  
Autoimmune Phenomena

Histiocytic necrotizing lymphadenitis, also known as Kikuchi-Fujimoto disease, is a disorder of lymph nodes originally described by Kikuchi1 and Fujimoto2 in 1972. Since 1982 this disorder has been increasingly recognized in the United States and worldwide, with the most extensive analyses of the disease presented by Dorfman et al.3-5 There has been little discussion of this entity in the pediatric literature. The most common presentation of necrotizing lymphadenitis includes fever and painless cervical lymphadenopathy. Patients may also present with weight loss, nausea, vomiting, diarrhea, chills, or diaphoresis. On occasion, myalgias, arthralgias, malar or butterfly rash, hepatomegaly, and splenomegaly have been noted.3

scholarly journals Kikuchi-Fujimoto Disease: A Rare Case Report from Nepal

2021 ◽  
Author(s):  
Rahul Rauniyar ◽  
Kshitiz Acharya ◽  
Aman Mishra ◽  
Nibesh Pathak ◽  
Gajendra Chaudhary ◽  
...  
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Rare Case ◽  
Cervical Lymphadenopathy ◽  
Differential Diagnoses ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Rare Case Report ◽  
Necrotizing Lymphadenitis ◽  
Limiting Condition

Kikuchi-Fujimoto Disease (KFD), also called histiocytic necrotizing lymphadenitis, is a rare benign self-limiting condition, commonly characterized by cervical lymphadenopathy and fever. KFD must be included in the differential diagnoses of lymphadenopathy. Clinicians and pathologists should be aware of the occurrence of this entity, for early diagnosis.

scholarly journals Is recurrent Kikuchi-Fujimoto disease a precursor to systemic lupus erythematosus?

2019 ◽  
Vol 57 (1) ◽  
pp. 72-77
Author(s):  
Taro Horino ◽  
Osamu Ichii ◽  
Yoshio Terada
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Cervical Lymphadenopathy ◽  
Clinical Entity ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Systemic Lupus ◽  
Necrotizing Lymphadenitis

Abstract Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign, self-limiting disease characterized by cervical lymphadenopathy and fever. Since KFD was first reported in 1972, the validity of this clinical entity has been controversial and its aetiology remains unknown. Herein, we report a case of a patient with KFD, which was believed to be associated with systemic lupus erythematosus.

scholarly journals Kikuchi necrotizing lymphadenopathy: a tip of the iceberg disease?

2021 ◽  
Vol 8 (9) ◽  
pp. 1602
Author(s):  
Sushil Singla ◽  
Mohitesh Kumar ◽  
Vinod Kumar Jat ◽  
Deepika Parwan
Keyword(s):  
Lymph Node ◽  
Laboratory Test ◽  
Young Patient ◽  
Healthy Individual ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Benign Condition ◽  
Node Biopsy ◽  
Necrotizing Lymphadenitis

Kikuchi-Fujimoto disease (KFD) is a rare benign condition also called histiocytic necrotizing lymphadenitis, which typically presented as fever with cervical lymphadenopathy in previously healthy individual. We presented a case of 11 year old boy with fever and cervical lymphadenopathy since 2 months. Lymph node biopsy was performed which suggested of KFD and was treated symptomatically. KFD incidence is rare but clinicians should be alert if young patient comes with fever and cervical lymphadenopathy to lower the chance of unwanted laboratory test and harmful treatment. 

scholarly journals Features of Sequential CT and US-guided Biopsy in Recurrent Kikuchi Disease of the Neck: A Case Report

2013 ◽  
Vol 92 (9) ◽  
pp. 442-448 ◽  
Author(s):  
Sang Kwon Lee ◽  
Young Eun Bahn ◽  
Dong Eun Kim
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Lymph Nodes ◽  
Complete Resolution ◽  
Tuberculous Lymphadenitis ◽  
Guided Biopsy ◽  
Initial Episode ◽  
Extensive Necrosis

A 26-year-old woman presented with recurrent Kikuchi disease 7 years after her initial episode. Computed tomography (CT) and ultrasonography demonstrated enlarged lymph nodes with extensive necrosis at the same site as the initial episode. Cytologic and histologic examinations were not conclusive. CT performed 1 month later demonstrated a complete resolution of the lymphadenopathy, which confirmed the diagnosis of recurrent Kikuchi disease. Care must be taken to avoid misdiagnosis of recurrent Kikuchi disease as tuberculous lymphadenitis.

scholarly journals Kikuchi-Fujimoto Disease: A Report of 3 Cases

2007 ◽  
Vol 86 (7) ◽  
pp. 412-413 ◽  
Author(s):  
Eimear Phelan ◽  
Emer Lang ◽  
Peter Gormley ◽  
John Lang
Keyword(s):  
Weight Loss ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Accurate Diagnosis ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Kikuchi’S Disease ◽  
Node Biopsy ◽  
Night Sweats ◽  
Necrotizing Lymphadenitis ◽  
Kikuchi's Disease

Cervical lymphadenopathy has many underlying etiologies. One of its rare causes is Kikuchi-Fujimoto disease (Kikuchi's disease, histiocytic necrotizing lymphadenitis). We discovered such a cause in a 37-year-old woman who had presented with malaise, night sweats, and weight loss in addition to cervical lymphadenopathy. We based our diagnosis on excisional lymph node biopsy. We also review 2 other cases of Kikuchi's disease that were diagnosed by others at our institution. Clinically and histologically, Kikuchi's disease is very similar to lymphoma, and distinguishing the two is difficult. However, despite the fact that Kikuchi's disease is benign, an accurate diagnosis is important because misdiagnosis might lead to unnecessary surgery and/or chemotherapy.

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