scholarly journals PsicquicGraph, a BioJS component to visualize molecular interactions from PSICQUIC servers

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 44 ◽  
Author(s):  
Jose M. Villaveces ◽  
Rafael C. Jimenez ◽  
Bianca H. Habermann

Summary: Protein interaction networks have become an essential tool in large-scale data analysis, integration, and the visualization of high-throughput data in the context of complex cellular networks. Many individual databases are available that provide information on binary interactions of proteins and small molecules. Community efforts such as PSICQUIC aim to unify and standardize information emanating from these public databases. Here we introduce PsicquicGraph, an open-source, web-based visualization component for molecular interactions from PSIQUIC services. Availability: PsicquicGraph is freely available at the BioJS Registry for download and enhancement. Instructions on how to use the tool are available here http://goo.gl/kDaIgZ and the source code can be found at http://github.com/biojs/biojs and DOI:10.5281/zenodo.7709.

2020 ◽  
Author(s):  
Diogo Borges Lima ◽  
Ying Zhu ◽  
Fan Liu

ABSTRACTSoftware tools that allow visualization and analysis of protein interaction networks are essential for studies in systems biology. One of the most popular network visualization tools in biology is Cytoscape, which offers a large selection of plugins for interpretation of protein interaction data. Chemical cross-linking coupled to mass spectrometry (XL-MS) is an increasingly important source for such interaction data, but there are currently no Cytoscape tools to analyze XL-MS results. In light of the suitability of Cytoscape platform but also to expand its toolbox, here we introduce XlinkCyNET, an open-source Cytoscape Java plugin for exploring large-scale XL-MS-based protein interaction networks. XlinkCyNET offers rapid and easy visualization of intra and intermolecular cross-links and the locations of protein domains in a rectangular bar style, allowing subdomain-level interrogation of the interaction network. XlinkCyNET is freely available from the Cytoscape app store: http://apps.cytoscape.org/apps/xlinkcynet and at https://www.theliulab.com/software/xlinkcynet.


2006 ◽  
Vol 5 (2) ◽  
pp. 67-72
Author(s):  
Yousuke Kimura ◽  
Tomohiro Mashita ◽  
Atsushi Nakazawa ◽  
Takashi Machida ◽  
Kiyoshi Kiyokawa ◽  
...  

We propose a new rendering system for large-scale, 3D geometic data that can be used with web-based content man-agement systems (CMS). To achieve this, we employed a geometry hierarchical encoding method "QSplat" and implemented this in a Java and JOGL (Java bindings of OpenGL) environment. Users can view large-scale geometric data using conventional HTML browsers with a non-powerful CPU and low-speed networks. Further, this system is independent of the platforms. We add new functionalities so that users can easily understand the geometric data: Annotations and HTML Synchronization. Users can see the geometric data with the associated annotations that describe the names or the detailed explanations of the particular portions. The HTML Synchronization enables users to smoothly and interactively switch our rendering system and HTML contents. The experimental results show that our system performs an interactive frame rate even for a large-scale data whereas other systems cannot render them


F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 50 ◽  
Author(s):  
Gustavo A. Salazar ◽  
Ayton Meintjes ◽  
Nicola Mulder

Summary: We present two web-based components for the display of Protein-Protein Interaction networks using different self-organizing layout methods: force-directed and circular. These components conform to the BioJS standard and can be rendered in an HTML5-compliant browser without the need for third-party plugins. We provide examples of interaction networks and how the components can be used to visualize them, and refer to a more complex tool that uses these components. Availability: http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.7753


2017 ◽  
Author(s):  
Julie A McMurry ◽  
Nick Juty ◽  
Niklas Blomberg ◽  
Tony Burdett ◽  
Tom Conlin ◽  
...  

AbstractIn many disciplines, data is highly decentralized across thousands of online databases (repositories, registries, and knowledgebases). Wringing value from such databases depends on the discipline of data science and on the humble bricks and mortar that make integration possible; identifiers are a core component of this integration infrastructure. Drawing on our experience and on work by other groups, we outline ten lessons we have learned about the identifier qualities and best practices that facilitate large-scale data integration. Specifically, we propose actions that identifier practitioners (database providers) should take in the design, provision and reuse of identifiers; we also outline important considerations for those referencing identifiers in various circumstances, including by authors and data generators. While the importance and relevance of each lesson will vary by context, there is a need for increased awareness about how to avoid and manage common identifier problems, especially those related to persistence and web-accessibility/resolvability. We focus strongly on web-based identifiers in the life sciences; however, the principles are broadly relevant to other disciplines.


2016 ◽  
Vol 6 (2) ◽  
pp. 76-82
Author(s):  
Antonius Rachmat ◽  
Yuan Lukito

Crowdsourced Labelling is a large scale data labelling process, solicits a large group of people to label the data, usually via Internet.  This paper discusses about design and implementation of Web-based Crowdsourced Labelling.  Supervised learning classification methods need labelled training data for its training phase.  Unfortunately, in many cases, there aren’t any already available labelled training data.  Large scale data labelling is a tedious and time consuming work.  This research develops a web-based crowdsourced labelling which able to solicit a large group of people as data labeler to speed up the data labelling process.  This system also allows multiple labeler for every data.  The final label is calculated using Weighted Majority Voting method.  We grabbed and used Facebook comments from the two candidates’ Facebook Page of 2014 Indonesian Presidential Election as testing data.  Based on the testing conducted we can conclude that this system is able to handle all the labelling steps well and able to handle collision occurred when multiple labeler labelling a same data in the same time. The system successfully produces final label in CSV format, which can be processed further with many sentiment analysis tools or machine learning tools. Index Terms - Crowdsources labeling, web-based system, supervised learning, weighted majority voting.


2009 ◽  
Vol 28 (11) ◽  
pp. 2737-2740
Author(s):  
Xiao ZHANG ◽  
Shan WANG ◽  
Na LIAN

Sign in / Sign up

Export Citation Format

Share Document