Current status and future prospects for enabling chemistry technology in the drug discovery process
Keyword(s):
This review covers recent advances in the implementation of enabling chemistry technologies into the drug discovery process. Areas covered include parallel synthesis chemistry, high-throughput experimentation, automated synthesis and purification methods, flow chemistry methodology including photochemistry, electrochemistry, and the handling of “dangerous” reagents. Also featured are advances in the “computer-assisted drug design” area and the expanding application of novel mass spectrometry-based techniques to a wide range of drug discovery activities.
2002 ◽
Vol 38
(6)
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pp. 355-364
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2020 ◽
Keyword(s):
2015 ◽
Vol 22
(15)
◽
pp. 1793-1807
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2009 ◽
Keyword(s):
2000 ◽
Vol 504
(1-3)
◽
pp. ix-x
1999 ◽
Vol 64
(23)
◽
pp. 8434-8456
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Keyword(s):