СIRCADIAN RHYTHMS OF BLOOD GAS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

2016 ◽  
Vol 1 (60) ◽  
pp. 34-38
Author(s):  
Горячева ◽  
Svetlana Goryacheva ◽  
Приходько ◽  
Olga Prikhodko ◽  
Кострова ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Circadian Rhythm ◽  
Respiratory System ◽  
Carbon Dioxide Tension ◽  
Capillary Blood ◽  
Chronic Obstructive ◽  
Gas Composition ◽  
Blood Gas ◽  
Healthy Individuals ◽  
Partial Oxygen

Chronobiological aspects of blood gas composition in 24 patients with COPD were studied. To achieve this goal, the gas composition of the arterialized capillary blood simultaneously with the investigation of respiratory function was studied with an interval of 6 hours over 2 days. In healthy individuals and patients with mild COPD two types of gas composition of blood biorhythm – daytime and nighttime – were found. In patients with moderate, severe and very severe disease 3 types of biorhythm of partial oxygen and carbon dioxide tension – morning time, noontime and evening time were registered. In healthy individuals and patients with mild COPD gas composition of blood was characterized by significant degrees of freedom in relation to functioning of the respiratory system, which indicated the stored processes of adaptation to changing conditions of the external and internal environment. In patients with moderate, severe and very severe COPD at the moment of acrophase of circadian rhythm of lung function maximum partial oxygen pressure in the arterialized capillary blood was observed. During the batiphaze of circadian rhythm of the respiratory system the highest values of the partial carbon dioxide tension were revealed. Thus, it was found out that with the growth of the severity of the disease in patients with COPD abnormal rhythms of blood gas composition are registered; the dependence of circadian rhythm of blood gas composition on the functioning of the respiratory apparatus increases.

Clinical evaluation of an instrument to measure carbon dioxide tension at the oxygenator gas outlet in cardiopulmonary bypass

Perfusion ◽  
2006 ◽  
Vol 21 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Frode Kristiansen ◽  
Jan Olav Høgetveit ◽  
Thore H Pedersen
Keyword(s):  
Carbon Dioxide ◽  
Cardiopulmonary Bypass ◽  
Venous Blood ◽  
Carbon Dioxide Tension ◽  
Circuit Board ◽  
Separate Analysis ◽  
Blood Gas ◽  
Arterial Blood ◽  
Gas Measurement ◽  
Venous Blood Gas

This paper presents the clinical testing of a new capno-graph designed to measure the carbon dioxide tension at the oxygenator exhaust outlet in cardiopulmonary bypass (CPB). During CPB, there is a need for reliable, accurate and instant estimates of the arterial blood CO2 tension (PaCO2) in the patient. Currently, the standard practice for measuring PaCO2 involves the manual collection of intermittent blood samples, followed by a separate analysis performed by a blood gas analyser. Probes for inline blood gas measurement exist, but they are expensive and, thus, unsuitable for routine use. A well-known method is to measure PexCO2, ie, the partial pressure of CO2 in the exhaust gas output from the oxygenator and use this as an indirect estimate for PaCO2. Based on a commercially available CO2 sensor circuit board, a laminar flow capnograph was developed. A standard sample line with integrated water trap was connected to the oxygenator exhaust port. Fifty patients were divided into six different groups with respect to oxygenator type and temperature range. Both arterial and venous blood gas samples were drawn from the CPB circuit at various temperatures. Alfa-stat corrected pCO2 values were obtained by running a linear regression for each group based on the arterial temperature and then correcting the PexCO2 accordingly. The accuracy of the six groups was found to be (±SD): ±4.3, ±4.8, ±5.7, ±1.0, ±3.7 and ±2.1%. These results suggest that oxygenator exhaust capnography is a simple, inexpensive and reliable method of estimating the PaCO2 in both adult and pediatric patients at all relevant temperatures.

An Extremely Simple and Fast Microlitre Method for the Determination of Total Carbon Dioxide in Biological Samples

1985 ◽  
Vol 22 (5) ◽  
pp. 509-513 ◽  
Author(s):  
G J Van Stekelenburg ◽  
C Valk ◽  
M J G Van Wijngaarden-Penterman
Keyword(s):  
Carbon Dioxide ◽  
Biological Fluids ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Capillary Blood ◽  
Total Carbon ◽  
Blood Gas ◽  
Carbon Dioxide Content ◽  
Simple Method

For those clinical laboratories equipped with a microprocessor-controlled gas analyser, an extremely simple method is described for the determination of the total carbon dioxide content in various biological fluids. Since this method needs only 20 μL of blood plasma or is less dependent on the original total carbon dioxide content, it is especially suited for paediatric purposes. With our procedure the time necessary for one determination equals the time for one capillary blood gas analysis.

Comparing arterial and end-tidal carbon dioxide values in hyperventilated neurosurgical patients

1995 ◽  
Vol 4 (2) ◽  
pp. 116-121 ◽  
Author(s):  
MA Christensen ◽  
J Bloom ◽  
KR Sutton
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Tension ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Arterial Carbon Dioxide ◽  
Arterial Blood ◽  
Neurosurgical Patients ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Monitoring ◽  
End Tidal

BACKGROUND: Hyperventilation is a frequently used method for inducing hypercarbia in neurosurgical patients. This practice requires careful carbon dioxide monitoring that might be replaced by a less expensive and less invasive alternative to arterial blood gas monitoring. OBJECTIVE: To determine the accuracy of end-tidal carbon dioxide monitoring in hyperventilated neurosurgical patients. METHODS: Nineteen adult patients requiring hyperventilation for the reduction of intracranial pressure following head injury or neurosurgery were enrolled from the surgical intensive care unit of a level I trauma center. A correlation design was used to compare arterial carbon dioxide tensions and end-tidal carbon dioxide measurements during specific periods; secondary analysis with bias and precision estimates was performed. Also, changes in arterial carbon dioxide tensions were compared with simultaneous changes in end-tidal carbon dioxide values. RESULTS: End-tidal carbon dioxide values showed a moderately acceptable correlation with arterial blood gas measurements. However, changes in end-tidal carbon dioxide values failed to correlate with simultaneous changes in arterial carbon dioxide tension measures. Bias and precision measures confirmed these findings. CONCLUSION: In this patient sample, changes in end-tidal carbon dioxide values did not accurately reflect changes in arterial carbon dioxide tension levels in the intensive care setting. Further technological advances in noninvasive carbon dioxide monitoring may lead to a significant cost savings over traditional arterial blood gas analysis.

Measuring carbon dioxide tension in saline and alternative solutions: Quantification of bias and precision in two blood gas analyzers

1994 ◽  
Vol 22 (1) ◽  
pp. 96-100 ◽  
Author(s):  
David Riddington ◽  
Keith Balasubramanian Venkatesh ◽  
Thomas Clutton-Brock ◽  
Julian Bion
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Tension ◽  
Blood Gas ◽  
Alternative Solutions
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