scholarly journals USE OF TRANSCRANIAL MAGNETIC STIMULATION IN CHILDREN WITH CONSEQUENCES OF PERINATAL BRAIN LESIONS

2016 ◽  
Vol 1 (6) ◽  
pp. 71-75
Author(s):  
Тимофеева ◽  
Olga Timofeeva ◽  
Алимова ◽  
Elena Alimova ◽  
Шпрах ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Clinical Performance ◽  
Clinical Signs ◽  
Low Frequency ◽  
Speech Development ◽  
Psychological Status ◽  
Neuroprotective Therapy ◽  
Stimulation Method

1249children of 5–10years (716boys, 533girls) with consequences of perinatal lesions of the CNS were examined, 230 of them were treated with the transcranial magnetic stimulation method (TMS). Selection of the TMS regimens was carried out taking into account the specific clinical neurophysiological features of the patients both as monotherapy, as well as a part of complex neurorehabilitation. For example, when intensifying of the synchronizing influences of tha-lamic structures and EEG signs of a delay of formation of electrical cortical rhythmicity, in children with developmental dysphasia and difficulties of school training, a high-pitched stimulation in the projection of the sensomotor and speech zones of a cerebral cortex was chosen; when intensifying of desynchronization influences of a reticular formation of a brainstem; at motor type of a developmental dysphasia and clinical signs of ADHD syndrome, a low-frequency regimen of stimulation of front-parietal and central areas of a cerebral cortex were chosen. Efficiency of therapy within 55–60% concerning indicators of the speech sphere and the psychological status is reached at sessions of TMS together with correctional occupations with auxiliary specialists of the rehabilitation center – speech pathologists and psychologists. Efficiency of monotherapy of TMS in children with retardation of psycho-speech development made 30–35%. Sufficient clinical performance and safety of the technique, a possibility of holding sessions of TMS against the background of course neuroprotective therapy at children with cerebral palsy is shown.

scholarly journals Blood flow and oxygenation changes due to low-frequency repetitive transcranial magnetic stimulation of the cerebral cortex

2013 ◽  
Vol 18 (6) ◽  
pp. 067006 ◽  
Author(s):  
Rickson C. Mesquita ◽  
Olufunsho K. Faseyitan ◽  
Peter E. Turkeltaub ◽  
Erin M. Buckley ◽  
Amy Thomas ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Stimulation Of

scholarly journals Benefits of Repetitive Transcranial Magnetic Stimulation (rTMS) for Spastic Subjects: Clinical, Functional, and Biomechanical Parameters for Lower Limb and Walking in Five Hemiparetic Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Luc Terreaux ◽  
Raphael Gross ◽  
Fabien Leboeuf ◽  
Hubert Desal ◽  
Olivier Hamel ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Premotor Cortex ◽  
Clinical Signs ◽  
Low Frequency ◽  
Spinal Reflexes ◽  
Plantar Flexors ◽  
Double Blind

Introduction.Spasticity is a disabling symptom resulting from reorganization of spinal reflexes no longer inhibited by supraspinal control. Several studies have demonstrated interest in repetitive transcranial magnetic stimulation in spastic patients. We conducted a prospective, randomized, double-blind crossover study on five spastic hemiparetic patients to determine whether this type of stimulation of the premotor cortex can provide a clinical benefit.Material and Methods.Two stimulation frequencies (1 Hz and 10 Hz) were tested versus placebo. Patients were assessed clinically, by quantitative analysis of walking and measurement of neuromechanical parameters (HandTreflexes, musculoarticular stiffness of the ankle).Results.No change was observed after placebo and 10 Hz protocols. Clinical parameters were not significantly modified after 1 Hz stimulation, apart from a tendency towards improved recruitment of antagonist muscles on the Fügl-Meyer scale. Only cadence and recurvatum were significantly modified on quantitative analysis of walking. Neuromechanical parameters were modified with significant decreases inHmax⁡/Mmax⁡andT/Mmax⁡ratios and stiffness indices 9 days or 31 days after initiation of TMS.Conclusion.This preliminary study supports the efficacy of low-frequency TMS to reduce reflex excitability and stiffness of ankle plantar flexors, while clinical signs of spasticity were not significantly modified.

scholarly journals Repetitive transcranial magnetic stimulation as a prophylactic treatment in migraine

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Azza B. Hammad ◽  
Rasha E. Elsharkawy ◽  
Ghada S. Abdel Azim
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Serum Level ◽  
Pain Intensity ◽  
Magnetic Stimulation ◽  
Prophylactic Treatment ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Control Group ◽  
Neurokinin A ◽  
Abortive Treatment

Abstract Background Clinical applications of transcranial magnetic stimulation (TMS) have shown promising results in the treatment of headache disorders, with migraine being one of the most encountered. Objective To assess the role of low-frequency repetitive transcranial magnetic stimulation as a preventive treatment of migraine (with and without aura) and correlate the results with the serum level of the inflammatory biomarker (neurokinin A). Methods Forty patients, with age ranging from 15 to 55 years, diagnosed with migraine (30 migraine without aura and 10 with aura) and 20 apparently healthy individuals, who were age and sex matched with the patient group, were included in this study. A low-frequency (1 Hz) rTMS protocol was applied for all patients for five consecutive days interictally. Assessment of pain intensity using visual analogue scale and frequency and duration of attacks as well as number of pills taken by patients as an abortive treatment according to the Basic Diagnostic Headache Diary for 4 weeks before and 4 weeks after TMS sessions was done. In addition, the Migraine Disability Assessment scale (MIDAS) was applied to assess the severity and degree of disability caused by migraine. Measurement of neurokinin A serum level was done by using ELISA for all patients before and after TMS and for control group once. Results There was a significant reduction in pain intensity, frequency and duration of migraine attacks, migraine disability scores, and number of pills taken as abortive treatment for attacks after rTMS (P < 0.001). Also, serum level of neurokinin A in the patients was significantly reduced after rTMS (P < 0.001). Conclusion Low-frequency rTMS is an effective prophylactic treatment for migraine with and without aura.

Sign in / Sign up

Export Citation Format

Share Document