Risk Assessment of Zoonotic Cutaneous Leishmaniasis Cases among Manual Workers in Egypt

2017 ◽  
Vol 47 (3) ◽  
pp. 559-574
Author(s):  
Mohamed Bakr El-Attar ◽  
Ahmed Megahed Ahmed Saleh ◽  
Nargis Albert Labib
Keyword(s):  
Risk Assessment ◽  
Cutaneous Leishmaniasis ◽  
Zoonotic Cutaneous Leishmaniasis

Eco-epidemiological aspects of Zoonotic cutaneous leishmaniasis in Ouarzazate Province, Morocco

2021 ◽  
Author(s):  
Ahmed Karmaoui ◽  
Fadoua El Qorchi ◽  
Lhoussain Hajji ◽  
Siham Zerouali
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Zoonotic Cutaneous Leishmaniasis

scholarly journals Zoonotic cutaneous leishmaniasis due to Leishmania (Viannia) braziliensis associated with domestic animals in Venezuela and Brazil

1989 ◽  
Vol 84 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Cruz Manuel Aguilar ◽  
Elizabeth F. Rangel ◽  
Leonardo Garcia ◽  
Elio Fernandez ◽  
Hooman Momen ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Rio De Janeiro ◽  
Domestic Animals ◽  
Source Of Infection ◽  
Zoonotic Cutaneous Leishmaniasis ◽  
Significant Difference ◽  
Janeiro State ◽  
Enzootic Cycle

After outbreaks of cutaneous leishmaniasis in Solano State, Venezuela, 5% of the population had parasitized ulcers while after similar outbreaks in Mesquita, Rio de Janeiro State, Brazil, 9% had the disease. In these foci children, including some under six years of age, wre affected. There was no significant difference in the occurence of the disease according to sex or type of employment. In Solano, 3% of dogs and 28% of donkeys had parasitized lesions, while in Mesquita these indices were 19.8% and 30.8% respectively. The parasite from man, dogs and equines was identified as Leishmania (Viannia) braziliensis, by zymodeme and serodeme characterization. In these foci there is evidence suggesting that leishmaniasis is a zoonosis, possibly with equine and dogs as reservoirs, although both a wild enzootic cycle and the role of man as a source of infection can not be ruled out. Transmission is assumed to occur peridomestically by sandfly vectors such as Lutzomyia panamensis in Venezuela and Lutzomyia intermedia in Brazil. Information about the origin of these foci suggests that infected equines may be an important factor in the dissemination of the parasite in a peridomestic situation where these sandflies are abundant.

Outbreak of Zoonotic Cutaneous Leishmaniasis with Local Dissemination in Balkh, Afghanistan

2012 ◽  
Vol 158 (3) ◽  
pp. 225-228 ◽  
Author(s):  
Mark S Bailey ◽  
AJ Caddy ◽  
KA McKinnon ◽  
LF Fogg ◽  
M Roscoe ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Zoonotic Cutaneous Leishmaniasis

scholarly journals Epidemiological features of a recent zoonotic cutaneous leishmaniasis outbreak in Zagora province, southern Morocco

2019 ◽  
Vol 13 (4) ◽  
pp. e0007321 ◽  
Author(s):  
Adil El Hamouchi ◽  
Othmane Daoui ◽  
Mouad Ait Kbaich ◽  
Idris Mhaidi ◽  
Sofia El Kacem ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Epidemiological Features ◽  
Zoonotic Cutaneous Leishmaniasis

Relationship Between the Distribution and Biodiversity of Sand Flies (Diptera: Psychodidae) With the Incidence of Zoonotic Cutaneous Leishmaniasis in Endemic Foci of Golestan Province, Iran

2020 ◽  
Vol 57 (6) ◽  
pp. 1768-1774
Author(s):  
Aioub Sofizadeh ◽  
Kamran Akbarzadeh ◽  
Ehsan Allah Kalteh ◽  
Fatemeh Karimi
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Diversity Index ◽  
Wiener Index ◽  
Sand Flies ◽  
Phlebotomus Papatasi ◽  
Light Traps ◽  
Phlebotomine Sand Flies ◽  
Zoonotic Cutaneous Leishmaniasis ◽  
Golestan Province ◽  
The Relationship

Abstract Zoonotic cutaneous leishmaniasis (ZCL) is prevalent in Golestan Province, Iran. The current study determined the relationship between the distribution and biodiversity of sand flies with cutaneous leishmaniasis at 14 villages in plain and hillsides areas. In each village from July to September 2017, 60 sticky traps and 2 CDC light traps were laid. Spearman and Mann–Whitney tests were used to determine the relationship between the incidence of ZCL and the abundance of different species of sand flies. Simpson, Shannon-Wiener, Evenness, and Margalef indices were calculated to estimate the diversity of species. A total of 5,295 phlebotomine sand flies were collected, comprising 10 species of the genus Phlebotomus (3,947 flies) and 7 species of genus Sergentomyia (1,248 flies). The abundance of sand flies and incidence of ZCL in plain areas were greater than that of hillsides areas (P = 0.013, P = 0.002). There was a significant correlation between the incidence of ZCL and the abundance of Phlebotomus papatasi (r = 0.72, P = 0.004) and P. caucasicus groups (P = 0.006; 0.022). In the Shannon-Wiener index, the rest of the biodiversity indices were reduced in higher-altitude areas. Increasing Shannon-Wiener index showed higher diversity of sand flies in higher-altitude areas. Data of the reported cases of leishmaniasis in plain areas can reveal the relationship between less diversity index (Shannon-Wiener), higher dominant diversity index (Simpson), and incidence of leishmaniasis in these areas.

scholarly journals Performance of an ELISA and Indirect Immunofluorescence Assay in Serological Diagnosis of Zoonotic Cutaneous Leishmaniasis in Iran

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Bahador Sarkari ◽  
Marzieh Ashrafmansouri ◽  
GholamReza Hatam ◽  
Parvaneh Habibi ◽  
Samaneh Abdolahi Khabisi
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Sensitivity And Specificity ◽  
Leishmania Major ◽  
Serological Test ◽  
Antibody Test ◽  
Immunofluorescence Assay ◽  
Enzyme Linked Immunosorbent Assay ◽  
Zoonotic Cutaneous Leishmaniasis ◽  
Proper Diagnosis ◽  
Indirect Immunofluorescent

Serological assays have been extensively evaluated for diagnosis of visceral leishmaniasis (VL) and considered as a routine method for diagnosis of VL while these methods are not properly evaluated for diagnosis of cutaneous leishmaniasis (CL). This study aimed to assess the performance of indirect immunofluorescent-antibody test (IFA) and enzyme-linked immunosorbent assay (ELISA) for serodiagnosis of cutaneous leishmaniasis in Iran. Sixty-one sera samples from parasitologically confirmed CL patients and 50 sera from healthy controls along with 50 sera from non-CL patients were collected. Antigen was prepared from promastigotes and amastigotes ofLeishmania major. IFA was used to detect anti-LeishmaniaIgG while ELISA was used to detect anti-LeishmaniaIgM, total IgG, or IgG subclasses (IgG1 and 4). ELISA, for detection of total IgG and IgM, showed sensitivity of 83.6% and 84.7% and specificity of 62.7% and 54.6%, respectively. Sensitivity and specificity of ELISA for detecting IgG1 and IgG4 were 64%, 75% and 85%, 49%, respectively. Sensitivity and specificity of IFA were 91.6% and 81%.Conclusion. Findings of this study demonstrated that serological test, especially IFA, can be used for proper diagnosis of CL.

scholarly journals Forecasting zoonotic cutaneous leishmaniasis using meteorological factors in eastern Fars province, Iran: a SARIMA analysis

2018 ◽  
Vol 23 (8) ◽  
pp. 860-869 ◽  
Author(s):  
Hamid Reza Tohidinik ◽  
Mehdi Mohebali ◽  
Mohammad Ali Mansournia ◽  
Sharareh R. Niakan Kalhori ◽  
Mohsen Ali-Akbarpour ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Meteorological Factors ◽  
Fars Province ◽  
Zoonotic Cutaneous Leishmaniasis

scholarly journals Histological and immunological differences between zoonotic cutaneous leishmaniasis due to Leishmania major and sporadic cutaneous leishmaniasis due to Leishmania infantum

Parasite ◽  
2019 ◽  
Vol 26 ◽  
pp. 9 ◽  
Author(s):  
Thouraya Boussoffara ◽  
Mohamed Samir Boubaker ◽  
Melika Ben Ahmed ◽  
Mourad Mokni ◽  
Ikram Guizani ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Histological Analysis ◽  
Quantitative Polymerase Chain Reaction ◽  
Immunohistochemical Analysis ◽  
Interferon Γ ◽  
Mrna Levels ◽  
Zoonotic Cutaneous Leishmaniasis ◽  
Chemotactic Protein ◽  
Polymerase Chain

Lesion features in cutaneous leishmaniasis (CL) depend on the infecting Leishmania species as well as on host immune reponse. In this study, we evaluated the histological and immunological differences between two forms of CL described in Tunisia: zoonotic cutaneous leishmaniasis (ZCL) caused by L. major and sporadic cutaneous leishmaniasis (SCL) caused by L. infantum. Histological analysis showed a mild to moderate infiltrate within ZCL lesions. In contrast, massive infiltration of the dermis was observed within SCL lesions. Contrary to ZCL, infiltrates within SCL lesions were organized and showed granuloma composed of macrophages and lymphocytes. In addition, immunohistochemical analysis showed a predominance of CD4+ T cells within both CL forms. Furthermore, expression of interferon-γ, interleukin (IL)-10, IL-8, IL-13 and monocyte chemotactic protein (MCP)-1 was evaluated using real-time quantitative polymerase chain reaction (RT-qPCR). MCP-1 and IL-10 were expressed at comparable levels in ZCL and SCL lesions. Interestingly, IL-8 mRNA levels were significantly higher in ZCL lesions compared to SCL lesions, but interferon-γ was significantly higher in SCL lesions than in ZCL lesions.

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