scholarly journals Impacts of Long-term Exposure to Fine Particulate Matter on Mortality Among the Elderly

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
X. Wu ◽  
D. Braun ◽  
J. Schwartz ◽  
M. Kioumourtzoglou ◽  
F. Dominici
2020 ◽  
Vol 189 (6) ◽  
pp. 602-612 ◽  
Author(s):  
Jinjun Ran ◽  
Aimin Yang ◽  
Shengzhi Sun ◽  
Lefei Han ◽  
Jinhui Li ◽  
...  

Abstract Numerous studies have indicated that ambient particulate matter is closely associated with increased risk of cardiovascular disease, yet the evidence for its association with renal disease remains underrecognized. We aimed to estimate the association between long-term exposure to fine particulate matter, defined as particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5), and mortality from renal failure (RF) among participants in the Elderly Health Service Cohort in Hong Kong, China, from 1998 to 2010. PM2.5 concentration at the residential address of each participant was estimated based on a satellite-based spatiotemporal model. We used Cox proportional hazards regression to estimate risks of overall RF and cause-specific mortality associated with PM2.5. After excluding 5,373 subjects without information on residential address or relevant covariates, we included 61,447 participants in data analyses. We identified 443 RF deaths during the 10 years of follow-up. For an interquartile-range increase in PM2.5 concentration (3.22 μg/m3), hazard ratios for RF mortality were 1.23 (95% confidence interval: 1.06, 1.43) among all cohort participants and 1.42 (95% confidence interval: 1.16, 1.74) among patients with chronic kidney disease. Long-term exposure to atmospheric PM2.5 might be an important risk factor for RF mortality in the elderly, especially among persons with existing renal diseases.


2019 ◽  
Vol 247 ◽  
pp. 874-882 ◽  
Author(s):  
Yang Yang ◽  
Zengliang Ruan ◽  
Xiaojie Wang ◽  
Yin Yang ◽  
Tonya G. Mason ◽  
...  

Author(s):  
Cavin K. Ward‐Caviness, ◽  
Mahdieh Danesh Yazdi, ◽  
Joshua Moyer, ◽  
Anne M. Weaver, ◽  
Wayne E. Cascio, ◽  
...  

Background Long‐term air pollution exposure is a significant risk factor for inpatient hospital admissions in the general population. However, we lack information on whether long‐term air pollution exposure is a risk factor for hospital readmissions, particularly in individuals with elevated readmission rates. Methods and Results We determined the number of readmissions and total hospital visits (outpatient visits+emergency room visits+inpatient admissions) for 20 920 individuals with heart failure. We used quasi‐Poisson regression models to associate annual average fine particulate matter at the date of heart failure diagnosis with the number of hospital visits and 30‐day readmissions. We used inverse probability weights to balance the distribution of confounders and adjust for the competing risk of death. Models were adjusted for age, race, sex, smoking status, urbanicity, year of diagnosis, short‐term fine particulate matter exposure, comorbid disease, and socioeconomic status. A 1‐µg/m 3 increase in fine particulate matter was associated with a 9.31% increase (95% CI, 7.85%–10.8%) in total hospital visits, a 4.35% increase (95% CI, 1.12%–7.68%) in inpatient admissions, and a 14.2% increase (95% CI, 8.41%–20.2%) in 30‐day readmissions. Associations were robust to different modeling approaches. Conclusions These results highlight the potential for air pollution to play a role in hospital use, particularly hospital visits and readmissions. Given the elevated frequency of hospitalizations and readmissions among patients with heart failure, these results also represent an important insight into modifiable environmental risk factors that may improve outcomes and reduce hospital use among patients with heart failure.


2019 ◽  
Vol 126 ◽  
pp. 568-575 ◽  
Author(s):  
Fengchao Liang ◽  
Xueli Yang ◽  
Fangchao Liu ◽  
Jianxin Li ◽  
Qingyang Xiao ◽  
...  

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