Hypoplastic Coronary Artery Disease Presenting with Ventricular Fibrillation Cardiac Arrest

Hypoplastic coronary artery disease is a rare congenital anomaly that may present with ischaemic heart disease, heart failure or sudden cardiac death (SCD). We describe a case of cardiac arrest in a healthy young man. Work-up revealed a hypoplastic left anterior descending artery. The patient underwent cardioverter-defibrillator implantation for secondary prevention.

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Angiotensin II and coronary artery disease, congestive heart failure, and sudden cardiac death

Basic Research in Cardiology ◽

10.1007/s003950050230 ◽

1998 ◽

Vol 93 (0) ◽

pp. s101-s108 ◽

Cited By ~ 10

Author(s):

R. Dietz ◽

R. von Harsdorf ◽

M. Gross ◽

J. Krämer ◽

D. Gulba ◽

...

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Congestive Heart Failure ◽

Coronary Artery ◽

Angiotensin Ii ◽

Sudden Cardiac Death ◽

Cardiac Death ◽

Artery Disease

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Hypoplastic coronary artery disease and hypertension in a child: a case report

European Heart Journal - Case Reports ◽

10.1093/ehjcr/ytab526 ◽

2021 ◽

Author(s):

Yuji Doi ◽

Kenji Waki ◽

Kayo Ogino ◽

Tomohiro Hayashi

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Sudden Cardiac Death ◽

Rare Disease ◽

Pediatric Patient ◽

Cardiac Death ◽

Acute Myocarditis ◽

Close Observation ◽

Artery Disease

Abstract Background Hypoplastic coronary artery disease (HCAD) is an extremely rare disease associated with a risk of sudden cardiac death. It is rarely recognized in a live pediatric patient. Case summary We report a case of HCAD in a patient who first presented with vomiting and poor feeding, suggestive of acute heart failure due to cardiomyopathy or acute myocarditis in infancy. Hypertension and signs of ischemia became evident on electrocardiography and scintigraphy after his cardiac function fully recovered, and he was diagnosed with HCAD by angiography performed at the age of eight years. He has remained under close observation with anti-hypertensives, aspirin, and exercise restriction. Discussion Although HCAD is a rare disease, it may not only cause ischemia but may also result in heart failure and sudden cardiac death. It should be considered in any pediatric patient with heart failure. Mid-term follow-up visits might be necessary to detect signs of ischemia in pediatric patients presenting with features of heart failure.

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Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease

Heart Rhythm ◽

10.1016/j.hrthm.2014.01.015 ◽

2014 ◽

Vol 11 (4) ◽

pp. 646-652 ◽

Cited By ~ 10

Author(s):

Marwan M. Refaat ◽

Bradley E. Aouizerat ◽

Clive R. Pullinger ◽

Mary Malloy ◽

John Kane ◽

...

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Cardiac Arrest ◽

Coronary Artery ◽

Sudden Cardiac Arrest ◽

Artery Disease

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Wearable cardioverter-defibrillator to reduce the transient risk of sudden cardiac death in coronary artery disease

EP Europace ◽

10.1093/europace/euaa045 ◽

2020 ◽

Vol 22 (10) ◽

pp. 1600-1600 ◽

Cited By ~ 1

Author(s):

Claude S Elayi ◽

Julia W Erath-Honold ◽

Reza Jabbari ◽

François Roubille ◽

Johanne Silvain ◽

...

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

Sudden Cardiac Death ◽

Cardiac Death ◽

Cardioverter Defibrillator ◽

Wearable Cardioverter Defibrillator ◽

Artery Disease

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Wearable cardioverter-defibrillator to reduce the transient risk of sudden cardiac death in coronary artery disease: Authors’ reply

EP Europace ◽

10.1093/europace/euaa052 ◽

2020 ◽

Vol 22 (10) ◽

pp. 1600-1601

Author(s):

Jacob Tfelt-Hansen ◽

Jesper Hastrup Svendsen ◽

Zbigniew Kalarus ◽

Davide Capodanno ◽

Gheorghe-Andrei Dan ◽

...

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

Sudden Cardiac Death ◽

Cardiac Death ◽

Cardioverter Defibrillator ◽

Wearable Cardioverter Defibrillator ◽

Artery Disease

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Diagnostic Value of Angiography-Derived IMR for Coronary Microcirculation and Its Prognostic Implication After PCI

Frontiers in Cardiovascular Medicine ◽

10.3389/fcvm.2021.735743 ◽

2021 ◽

Vol 8 ◽

Author(s):

Neng Dai ◽

Wenliang Che ◽

Lu Liu ◽

Wen Zhang ◽

Guoqing Yin ◽

...

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Cardiac Death ◽

Prognostic Value ◽

Moderate Correlation ◽

Fractional Flow ◽

Flow Reserve ◽

Artery Disease ◽

Diagnostic And Prognostic Value

Background: Angiography-derived index of microcirculatory resistance (angio-IMR) is an emerging pressure-wire-free index to assess coronary microvascular function, but its diagnostic and prognostic value remains to be elucidated.Methods and Results: The study population consisted of three independent cohorts. The internal diagnostic cohort enrolled 53 patients with available hyperemic microcirculatory resistance (HMR) calculated from myocardial blood flow and pressure. The external diagnostic cohort included 35 ischemia and no obstructive coronary artery disease (INOCA) patients and 45 controls. The prognostic cohort included 138 coronary artery disease (CAD) patients who received PCI. Angio-IMR was calculated after the estimation of angiography-derived fractional flow reserve (angio-FFR) using the equation of angio-IMR = estimated hyperemic Pa × angio-FFR × [vessel length/(K × Vdiastole)]. The primary outcome was a composite of cardiac death or readmission due to heart failure at 28 months after index procedure. Angio-IMR demonstrated a moderate correlation with HMR (R = 0.74, p < 0.001) and its diagnostic accuracy, sensitivity, specificity, and area under the curve to diagnose INOCA were 79.8, 83.1, 78.0, and 0.84, respectively, with a best cut-off of 25.1. Among prognostic cohort, patients with angio-IMR ≥25.1 showed a significantly higher risk of cardiac death or readmission due to heart failure than those with an angio-IMR <25.1 (18.6 vs. 5.4%, adjusted HR 9.66, 95% CI 2.04–45.65, p = 0.004). Angio-IMR ≥25.1 was an independent predictor for cardiac death or readmission due to heart failure (HR 11.15, 95% CI 1.76–70.42, p = 0.010).Conclusions: Angio-IMR showed a moderate correlation with HMR and high accuracy to predict microcirculatory dysfunction. Angio-IMR measured after PCI predicts the risk of cardiac death or readmission due to heart failure in patients with CAD.Clinical Trial Registration: Diagnostic and Prognostic Value of Angiography-derived IMR (CHART-MiCro), NCT04825028.

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Cardiac Arrest Prediction by Using Brain Wave

International Journal of Scientific Research in Science Engineering and Technology ◽

10.32628/ijsrset196283 ◽

2019 ◽

pp. 342-344

Author(s):

R. Gayathri ◽

Kanchi Harinath Jahnavi ◽

B. Shreenidhi ◽

D. Arul Kumar

Keyword(s):

Coronary Artery Disease ◽

Cardiac Arrest ◽

Coronary Artery ◽

Sudden Cardiac Death ◽

Cardiac Death ◽

Threshold Value ◽

Brain Wave ◽

Artery Disease

Sudden cardiac death (SCD) is a major cause of mortality secondary coronary artery disease (CAD) in modern societies. To avoid and create aware on that we are presenting a paper on idea about brain wave, brain and heart relation with this we can predict cardiac arrest. By this we can automatically operate defibrillator with setting a threshold value to avoid sudden cardiac death.

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Incidence of cardiovascular diseases in a nationwide HIV/AIDS patient cohort in Taiwan from 2000 to 2014

Epidemiology and Infection ◽

10.1017/s0950268818002339 ◽

2018 ◽

Vol 146 (16) ◽

pp. 2066-2071 ◽

Cited By ~ 1

Author(s):

Yun-Ju Lai ◽

Yu-Yen Chen ◽

Hsin-Hui Huang ◽

Ming-Chung Ko ◽

Chu-Chieh Chen ◽

...

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Cardiac Death ◽

Coronary Artery Bypass Surgery ◽

Bypass Surgery ◽

Artery Bypass ◽

Coronary Intervention ◽

Percutaneous Coronary ◽

Artery Disease

AbstractThe purpose of the study was to determine the incidence of cardiovascular disease (CVD) among people living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (PLWHA) in Taiwan. PLWHA were identified from the Taiwan Centers for Disease Control HIV Surveillance System between 2000 and 2014. To examine the effect of active antiretroviral therapy (HAART) on CVD incidence, incidence densities and standardised incidence rates (SIRs) of CVD were calculated after stratifying PLWHA by HAART. Of 26 272 PLWHA (mean age, 32.3 years) identified, 73.4% received HAART. Compared with general population, SIRs (95% confidence interval) were higher for incident coronary artery disease (1.11 (1.04–1.19)), percutaneous coronary intervention (1.32 (1.18–1.47)), coronary artery bypass surgery (1.47 (1.29–1.66)), sudden cardiac death (3.01 (2.39–3.73)), heart failure (1.50 (1.31–1.70)) and chronic kidney disease (1.95 (1.81–2.10)), but was lower for incident atrial fibrillation (0.53 (0.37–0.73)). Considering the effect of HAART on incident CVD, the SIRs for all-cause, ischaemic and haemorrhagic stroke were higher in PLWHA who did not receive HAART, but were lower in PLWHA who received HAART. PLWHA had higher risks of incident coronary artery disease, percutaneous coronary intervention, coronary artery bypass surgery, sudden cardiac death, heart failure and chronic kidney disease. HAART reduces risks of incident CVD in PLWHA.

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Does multivessel revascularization fit all patients with STEMI and multivessel coronary artery disease? a systematic review and meta-analysis

European Journal of Preventive Cardiology ◽

10.1093/eurjpc/zwab061.073 ◽

2021 ◽

Vol 28 (Supplement_1) ◽

Author(s):

H Mengjin ◽

YJ Yang

Keyword(s):

Heart Failure ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Cardiogenic Shock ◽

Cardiac Death ◽

Meta Analysis ◽

Multivessel Coronary Artery Disease ◽

Short Term ◽

All Cause Mortality ◽

Artery Disease

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): CAMS Innovation Fund for Medical Sciences Objective We sought to assess the relative merits of different revascularization strategies in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease complicated by cardiogenic shock or chronic total occlusion (CTO). Background Recent randomized trials and meta-analysis have suggested that multivessel percutaneous coronary intervention (PCI) is associated with better outcomes in patients with STEMI and multivessel coronary artery disease, however, patients complicated by cardiogenic shock or CTO were excluded. Methods Studies that compared multivessel PCI (immediate or staged) with culprit-only PCI in patients with STEMI and multivessel coronary artery disease complicated by cardiogenic shock or CTO were included. Random odd ratio (OR) and 95% confidence interval (CI) were conducted. Results Sixteen studies with 8695 patients complicated by cardiogenic shock and eight studies with 2259 patients complicated by CTO were included. In patients complicated by cardiogenic shock, a strategy of CO-PCI was associated with lower risk for short-term renal failure (OR: 0.75; 95% CI: 0.61 to 0.93; I2 = 0.0%), with no significant difference in MACE, all-cause mortality, re-infarction, revascularization, cardiac death, heart failure, major bleeding, or stroke compared with an immediate MV-PCI strategy. In patients complicated by CTO, a strategy of CO-PCI was associated with higher risk for long-term MACE (OR: 2.06; 95% CI: 1.39 to 3.06; I2 = 54.0%), all-cause mortality (OR: 2.89; 95% CI: 2.09 to 4.00; I2 = 0.0%), cardiac death (OR: 3.12; 95% CI: 2.05 to 4.75; I2 = 16.8%), heart failure (OR: 1.99; 95% CI: 1.22 to 3.24; I2 = 0.0%), and stroke (OR: 2.80; 95% CI: 1.04 to 7.53; I2 = 0.0%) compared with a staged MV-PCI strategy, without any difference in re-infarction, revascularization, or major bleeding. Conclusions For patients with STEMI and multivessel coronary artery disease complicated by cardiogenic shock, an immediate multivessel PCI was not advocated due to higher risk for short-term renal failure, whereas for patients complicated by CTO, a staged multivessel PCI was advocated due to reduced risks for MACE, all-cause mortality, cardiac death, heart failure, and stroke.

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