N-Methyl-D-Aspartate Receptor-Mediated Chronic Pain: New Approaches to Fibromyalgia Syndrome Etiology and Therapy

2007 ◽  
Vol 15 (2) ◽  
pp. 33-44 ◽  
Author(s):  
Samuel DeMaria ◽  
Afton L. Hassett ◽  
Leonard H. Sigal
Keyword(s):  
Chronic Pain ◽  
Fibromyalgia Syndrome ◽  
New Approaches ◽  
Aspartate Receptor

scholarly journals Ketamine for pain

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1711 ◽  
Author(s):  
Kelly Jonkman ◽  
Albert Dahan ◽  
Tine van de Donk ◽  
Leon Aarts ◽  
Marieke Niesters ◽  
...  
Keyword(s):  
Emergency Department ◽  
Chronic Pain ◽  
Side Effects ◽  
Postoperative Pain ◽  
Cancer Pain ◽  
Literature Search ◽  
Analgesic Agent ◽  
Aspartate Receptor ◽  
Persistent Postoperative Pain ◽  
Meta Analyses

The efficacy of theN-methyl-D-aspartate receptor antagonist ketamine as an analgesic agent is still under debate, especially for indications such as chronic pain. To understand the efficacy of ketamine for relief of pain, we performed a literature search for relevant narrative and systematic reviews and meta-analyses. We retrieved 189 unique articles, of which 29 were deemed appropriate for use in this review. Ketamine treatment is most effective for relief of postoperative pain, causing reduced opioid consumption. In contrast, for most other indications (that is, acute pain in the emergency department, prevention of persistent postoperative pain, cancer pain, and chronic non-cancer pain), the efficacy of ketamine is limited. Ketamine’s lack of analgesic effect was associated with an increase in side effects, including schizotypical effects.

Evaluation of Cytokine Levels in Fibromyalgia Syndrome Patients and its Relationship to the Severity of Chronic Pain†

2012 ◽  
Vol 20 (3) ◽  
pp. 164-169 ◽  
Author(s):  
Dipti Malhotra ◽  
Ashok Kr. Saxena ◽  
Sajjad A. Dar ◽  
Vivek Kumar ◽  
Namita Nasare ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Fibromyalgia Syndrome ◽  
Cytokine Levels

scholarly journals Toward a Transdisciplinary Integration of the Health Disciplines: The Case of the Fibromyalgia Syndrome

2017 ◽  
Vol 23 (1-2) ◽  
pp. 155-171
Author(s):  
Emanuele Maria Giusti
Keyword(s):  
Chronic Pain ◽  
Fibromyalgia Syndrome ◽  
Pain Disorder ◽  
Social Aspects ◽  
Care Providers ◽  
Chronic Pain Disorder ◽  
Disciplinary Boundaries ◽  
Interdisciplinary Programs

Abstract Fibromyalgia is a chronic pain disorder with a multifaceted nature and its biological, psychological and social aspects are strongly interconnected. Therefore, the integration of the different health disciplines is strongly recommended for its care. There is a growing number of interventions based on this principle but each of them is heterogeneous with regards to how the included disciplines are integrated with each other. With this regards, multidisciplinary and interdisciplinary programs are distinguished. The former are organized in order to treat the various aspects of the syndrome using different perspectives and their various treatment components are usually provided separately by the different care providers. Conversely, interdisciplinary treatments are planned in order to foster a dialogue between the operators by providing a joint conduction of the treatment or scheduling plenary discussions about the cases. In the field of chronic pain, some authors are suggesting to move beyond these approaches and to plan transdisciplinary treatments, which would allow the professionals to move across their disciplinary boundaries. Although no examples of these interventions have been proposed for the treatment of fibromyalgia, there is a visible trend in the literature toward more holistic forms of care.

Vibroacoustic treatment for chronic pain and mood disorders in a specialized healthcare setting

2017 ◽  
Vol 9 (3) ◽  
pp. 187
Author(s):  
Elsa Anne Campbell ◽  
Jouko Hynynen ◽  
Esa Ala-Ruona
Keyword(s):  
Chronic Pain ◽  
Clinical Trials ◽  
Fibromyalgia Syndrome ◽  
Case Reports ◽  
Healthcare Setting ◽  
Positive Outcomes ◽  
Central Hospital ◽  
Rehabilitation Unit ◽  
Visual Analog Scales ◽  
Patient Responses

Much of what we know about vibroacoustic treatment and its efficacy has been published in case reports. Recent clinical trials have increased awareness and understanding of this treatment for people with Parkinson’s disease or Fibromyalgia Syndrome. There are no standardized protocols for using vibroacoustic treatment although research has focused on using 40Hz. The rehabilitation unit of [blinded] Central Hospital in [blinded] has used vibroacoustic treatment for more than two decades as part of specialized healthcare in the [blinded] healthcare district. Patient responses have been recorded using Visual Analog Scales showing positive outcomes on several measures including pain and mood. This paper describes vibroacoustic treatment used within this unit, focusing on pain and mood outcomes reported in subjective patient evaluations and comments. 

Pain-Related Activity Management Patterns as Predictors of Treatment Outcomes in Patients with Fibromyalgia Syndrome

Pain Medicine ◽  
2019 ◽  
Author(s):  
Mélanie Racine ◽  
Elisabet Sánchez-Rodríguez ◽  
Rocío de la Vega ◽  
Santiago Galán ◽  
Ester Solé ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Physical Function ◽  
Fibromyalgia Syndrome ◽  
Activity Patterns ◽  
Post Treatment ◽  
Pain Interference ◽  
Psychological Function ◽  
Related Activity ◽  
Activity Management ◽  
Treatment Changes

Abstract Objectives This study sought to determine if pre- to post-treatment changes in pain-related activity patterns (i.e., overdoing, avoidance, and pacing) were associated with pre- to post-treatment changes in function (i.e., pain interference, psychological function, and physical function) in patients with fibromyalgia syndrome who participated in either an operant learning– or an energy conservation–based training in activity management. Methods Sixty-nine patients with fibromyalgia syndrome participated in an activity management treatment (32 in an operant learning group and 37 in an energy conservation group). Outcomes were assessed at pre- and post-treatment, and patients provided demographic information and completed measures assessing pain intensity, pain interference, psychological function, physical function, and pain management activity patterns. Three linear hierarchical regression analyses predicting changes in pain outcomes from changes in pacing, overdoing, and avoidant activity patterns were performed. Results Changes in pain-related activity patterns made significant contributions to the prediction of changes in patients’ function. Specifically: (a) increases in overdoing predicted reductions in pain interference; (b) decreases in avoidance predicted improvements in psychological function; and (c) increases in pacing predicted improvements in physical function. Conclusions This study provides support for a role of activity management treatments in improved adjustment to chronic pain. Research is needed to replicate and extend these findings in order to build an empirical basis for developing more effective chronic pain treatments for facilitating improved physical and psychological function in individuals with chronic pain.

Fibrositis/fibromyalgia syndrome: the key to the puzzle of chronic pain

1990 ◽  
Vol 152 (5) ◽  
pp. 226-228 ◽  
Author(s):  
Paul A. Reilly ◽  
Geoffrey O. Littlejohn
Keyword(s):  
Chronic Pain ◽  
Fibromyalgia Syndrome

scholarly journals Management of fibromyalgia syndrome

2018 ◽  
Vol 87 (1) ◽  
pp. 34-37
Author(s):  
Joshua Y Lee ◽  
Stacey D Guy ◽  
Michael J Lukacs ◽  
Zoe A Letwin ◽  
Mohamad F Fakhereddin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Emotional Response ◽  
Fibromyalgia Syndrome ◽  
Behavioral Therapy ◽  
Exercise Program ◽  
Thought Processes ◽  
Chronic Pain Condition ◽  
Maladaptive Thought

Fibromyalgia syndrome is a chronic pain condition that affects 440,000 Canadians above the age of 12. People with fibromyalgia report lifelong biological, emotional, cognitive and social complications. Recent clinical practice guidelines indicate management of symptoms is limited outside of analgesics. Cognitive-behavioral therapy (CBT) is one emerging treatment that displays promise for these individuals. CBT helps individuals to realize their maladaptive thought processes and how these can affect their own emotional response as well as the significance they attribute to potentially noxious stimuli. In conjunction with a physical exercise program, CBT shows promise in both the management of pain, and an improvement of quality of life.

scholarly journals SIMULACIÓN DE SÍNTOMAS EN PACIENTES CON FIBROMIALGIA

2017 ◽  
Vol 2 (1) ◽  
pp. 571
Author(s):  
Carlos Barbosa Torres ◽  
Sixto Cubo Delgado ◽  
Florencio Vicente Castro
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Health Survey ◽  
Fibromyalgia Syndrome ◽  
Pain Scale ◽  
Psychological Variables ◽  
Calidad De Vida ◽  
Sf 36 ◽  
Methods Of Control

Abstract.SIMULATION OF SYMPTOMS IN PATIENTS WITH FIBROMYALGIAIn this paper we find a study about the variable of simulation of symptoms in fibromyalgia syndrome regarding to other psychological variables such as quality of life, depression, anxiety as well as gradation of pain. The study was performed with 40 patients, all diagnosed with fibromyalgia by the criteria of the American Rheumatology Association. The instruments used were the Structured Inventory of Malingered Symptomatology (SIMS), the Graded Chronic Pain Scale and SF-36 Health Survey (SF-36v2). The results show that there is a relationship between the simulation of symptoms and chronic pain but not with quality of life. The simulation of symptoms in patients with fibromyalgia is a very complex phenomenon that depends on several methods of control among which it is possible to emphasize the use of screening like the SIMS supported with important physical and psychological examinations by experts.Key words: Fibromyalgia, chronic pain, symptom simulation.Resumen.En el presente trabajo encontramos un estudio sobre la variable simulación de síntomas en pacientes con fibromialgia en relación con otras variables psicológicas como calidad de vida, depresión y ansiedad al igual que la gradación del dolor. El estudio se realizó con un total de 40 pacientes todos diagnosticados con fibromialgia por los criterios de la Asociación Americana de Reumatología. Los instrumentos utilizados fueron, el Inventario Estructurado de Simulación de síntomas (SIMS), el Graded Chronic Pain Scale y el SF-36 Health Survey (SF-36v2) o Cuestionario autogestionado de Salud SF-36. Los resultados expuestos muestran que existen relación entre la simulación de síntomas dolor crónico pero no con la calidad de vida. La simulación de síntomas en pacientes con fibromialgia es un fenómeno muy complejo que depende de varios métodos de control entre los que cabe destacar la utilización de screening como el SIMS apoyados con importantes exámenes físicos y psicológicos por expertos.Palabras clave: Fibromialgia, dolor crónico, simulación de síntomas.

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