scholarly journals Evaluation of Nootropic Potential of Leucaena leucocephala on Wister Rats

2022 ◽  
Vol 10 (1) ◽  
pp. 8-17
Author(s):  
Jesanto Mathew ◽  
Chakrakodi Shashidhara Shastry ◽  
Sharad Chand
2018 ◽  
Vol 2 (2) ◽  
pp. 63-70 ◽  
Author(s):  
R. Obour

Broussonetia papyrifera is an exotic tree widely grown for paper production. Due to its prolific regeneration it has invaded forestcanopy gaps and degraded farmlands and has now become an invasive species in Ghana. In enhancing its value for use the plantwas evaluated as potential forage for grazing animals vis-à-vis other two existing forage plants: Ficus exasperata and Leucaenaleucocephala.The study assessed the palatability and preference of Broussonetia papyrifera using sheep and goats for the wet anddry seasons.The species were assessed in indoor pen feeding trials using eight-unit (3×3 m) pens with the cafeteria method.The amount of forage offered was 100g (fresh material) in all instances for each species and for ten minutes. Adesign basedon 3×2×2 factorial in Randomized Complete Block Design (RCBD) was used to test the differences in palatability betweenthe three forage species.Results revealed that palatability was higher (P<0.05) in Leucaena leucocephala compared with Ficusexasperata and Broussonetia papyrifera for sheep and goats across seasons. The trend shown might be the result of the effectsof familiarity with the Leucaena leucocephala since animals tend to select plants that are familiar than newly introduced andunfamiliar plants. The study also revealed high level of condensed tannin (CT) in Broussonetia papyrifera which might haveinterfered with forage intake by the animals.There were no significant differences in palatability of Broussonetia papyrifera forgoat in both dry and wet season interactions and Ficus exasperata for goat in both dry and wet season interactions (P>0.05).Thestudy concluded that Broussonetia papyrifera could be a potential feed for both sheep and goats across seasons.The researchrecommended that livestock farmers should incorporate Broussonetia papyrifera feed into their programmes for both sheep andgoats and should be introduced to animals from infancy so that it may become a familiar feed for them.


Author(s):  
Jena Hayu Widyasti ◽  
Fitri Kurniasari

Diabetes melitus merupakan suatu penyakit dengan adanya gangguan sekresi insulin baik karena penurunan sensitifitas maupun kerusakan pada sel beta. Tujuan penelitian ini adalah membuktikan ekstrak daun petai cina (Leucaena leucocephala (Lam.) de Wit) memiliki aktivitas menurunkan kadar gula darah mencit hiperglikemik pada dosis yang efektif. Penelitian antihiperglikemik ini menggunakan mencit putih sebanyak 30 ekor. Pengujian aktivitas antihiperglikemik dilakukan pada 6 kelompok perlakuan yaitu kelompok I (kontrol normal), kelompok II (kontrol negatif, induksi aloksan 200 mg/kg BB dan akuades), kelompok III (induksi aloksan dan glibenklamida 10 mg/kg BB), kelompok IV (induksi aloksan dan ekstrak daun petai cina 200 mg/kg BB), kelompok V (induksi aloksan dan ekstrak daun petai cina 400 mg/kg BB), kelompok VI (induksi aloksan dan ekstrak daun petai cina 300 mg/kg BB). Semua kelompok perlakuan diberikan perlakuan tersebut selama 14 hari dan dilakukan pengukuran kadar gula darah pada hari ke-0, 3, 10, dan 17. Aktivitas antihiperglikemik ekstrak daun petai cina ditunjukkan dengan cara menghitung daya hipoglikemik masing-masing perlakuan. Hasil penelitian menunjukkan bahwa ekstrak etanol daun petai cina mempunyai aktivitas antihiperglikemik pada mencit yang diinduksi aloksan. Pada dosis uji ekstrak etanol daun petai cina 600 mg/kg BB mempunyai aktivitas antihiperglikemik yang efektif dibanding dengan dosis 400 mg/kg BB dan 200 mg/kg BB yang sebanding dengan kelompok kontrol positif.


2013 ◽  
Vol 43 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Geraldo Pereira Junior ◽  
Manoel Pereira Filho ◽  
Rodrigo Roubach ◽  
Paula de Sousa Barbosa ◽  
Eduardo Shimoda

O tambaqui (Colossoma macropomum) é um peixe onívoro, natural da bacia amazônica, que possui elevado valor comercial. Características de rusticidade e desempenho produtivo destacam esta espécie para criação em cativeiro. Contudo, em criações comerciais de peixes, os custos com alimentação podem corresponder de 60 a 80% dos custos totais de produção, sendo a proteína o nutriente mais caro da dieta. O objetivo deste trabalho foi avaliar o desempenho produtivo de juvenis de tambaqui alimentados com rações contendo farinha de folha de leucena como fonte protéica. 240 juvenis foram distribuídos em 12 aquários experimentais (350 L), em um delineamento experimental inteiramente casualizado com quatro tratamentos (0%, 8%, 16%, 24% de inclusão de farinha de folha de leucena na ração) e três repetições. Foram determinados o ganho de peso, conversão alimentar aparente, taxa de crescimento específico, taxa de eficiência protéica e custo de produção do quilograma de peso vivo ganho. Para as variáveis estudadas, não houve diferença significativa (p>0,05) entre os tratamentos, indicando que é possível incluir até 24% de farinha de folha de leucena em rações para juvenis de tambaqui, sem comprometimento das variáveis estudadas, embora a substituição não tenha representado redução no custo de produção do quilograma de peixe.


Author(s):  
Sridevi Chigurupati ◽  
Shantini Vijayabalan ◽  
Kesavanarayanan Krishnan Selvarajan ◽  
Ahmad Alhowail ◽  
Fatema Kauser

AbstractObjectivesResearch on endosymbionts is emerging globally and is considered as a potential source of bioactive phytochemicals. The present study examines the antioxidant and antidiabetic of the endophytic crude extract isolated from Leucaena leucocephala leaves.MethodsEndophytic bacteria were isolated from the leaves of L. leucocephala and 16S rRNA gene sequencing was used to establish their identity. The in vitro antioxidant effect of endophytic crude extract (LL) was evaluated using 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) free radical scavenging methods. The in vitro antidiabetic properties of LL were evaluated using α-amylase and α-glucosidase enzyme inhibition assay.ResultsThe isolated endophytic bacteria were identified as Cronobacter sakazakii. LL displayed potent free radical scavenging effect against ABTS and DPPH radicals with an inhibitory concentration 50% (IC50) value of 17.49 ± 0.06 and 11.3 ± 0.1 μg/mL respectively. LL exhibited α-amylase and α-glucosidase inhibition with an IC50 value of 23.3 ± 0.08 and 23.4 ± 0.1 μg/mL respectively compared to the standard drug (acarbose). Both glucose loaded normoglycemic rats and STZ induced diabetic rats treated with LL (200 mg/kg) exhibited a considerable reduction in blood glucose levels p<0.01 after 8 h of treatment when compared to normal and diabetic control rats respectively.ConclusionsThus, the study shows that LL has a wellspring of natural source of antioxidants, and antidiabetic agents and phytoconstituents present in endophytes could be the rich source for bioactive compounds.


Author(s):  
S. Pramod ◽  
M. Anju ◽  
H. Rajesh ◽  
A. Thulaseedharan ◽  
Karumanchi S. Rao

AbstractPlant growth regulators play a key role in cell wall structure and chemistry of woody plants. Understanding of these regulatory signals is important in advanced research on wood quality improvement in trees. The present study is aimed to investigate the influence of exogenous application of 24-epibrassinolide (EBR) and brassinosteroid inhibitor, brassinazole (BRZ) on wood formation and spatial distribution of cell wall polymers in the xylem tissue of Leucaena leucocephala using light and immuno electron microscopy methods. Brassinazole caused a decrease in cambial activity, xylem differentiation, length and width of fibres, vessel element width and radial extent of xylem suggesting brassinosteroid inhibition has a concomitant impact on cell elongation, expansion and secondary wall deposition. Histochemical studies of 24-epibrassinolide treated plants showed an increase in syringyl lignin content in the xylem cell walls. Fluorescence microscopy and transmission electron microscopy studies revealed the inhomogenous pattern of lignin distribution in the cell corners and middle lamellae region of BRZ treated plants. Immunolocalization studies using LM10 and LM 11 antibodies have shown a drastic change in the micro-distribution pattern of less substituted and highly substituted xylans in the xylem fibres of plants treated with EBR and BRZ. In conclusion, present study demonstrates an important role of brassinosteroid in plant development through regulating xylogenesis and cell wall chemistry in higher plants.


2021 ◽  
Vol 709 (1) ◽  
pp. 012058
Author(s):  
N I Wiratmini ◽  
I Setyawati ◽  
D A Warmadewi ◽  
N L E Setiasih

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