Bulk hemoglobin, lipid and water content in the female breast from multi-wavelength time-resolved optical mammography

2004 ◽  
Author(s):  
Lorenzo Spinelli ◽  
Alessandro Torricelli ◽  
Antonio Pifferi ◽  
Paola Taroni ◽  
Rinaldo Cubeddu ◽  
...  
Keyword(s):  
Water Content ◽  
Time Resolved ◽  
Optical Mammography ◽  
Female Breast ◽  
Multi Wavelength

Characterization of female breast lesions from multi-wavelength time-resolved optical mammography

2005 ◽  
Vol 50 (11) ◽  
pp. 2489-2502 ◽  
Author(s):  
Lorenzo Spinelli ◽  
Alessandro Torricelli ◽  
Antonio Pifferi ◽  
Paola Taroni ◽  
Gianmaria Danesini ◽  
...  
Keyword(s):  
Breast Lesions ◽  
Time Resolved ◽  
Optical Mammography ◽  
Female Breast ◽  
Multi Wavelength

Multi-wavelength Time Domain Optical Mammography

2005 ◽  
Vol 4 (5) ◽  
pp. 527-537 ◽  
Author(s):  
P. Taroni ◽  
L. Spinelli ◽  
A. Torricelli ◽  
A. Pifferi ◽  
G.M. Danesini ◽  
...  
Keyword(s):  
Diffusion Theory ◽  
Lesion Detection ◽  
Tissue Composition ◽  
Absorption Properties ◽  
Time Resolved ◽  
Optical Mammography ◽  
Composition And Structure ◽  
Fitting Procedures ◽  
Multi Wavelength ◽  
Intensity Images

A time-resolved optical mammograph operating at 7 wavelengths (637, 683, 785, 832, 905, 916, and 975 nm) in compressed breast geometry was developed. Its clinical application was started on patients bearing malignant and benign lesions. Late gated intensity images are used to obtain information on the spatial distribution of the absorption properties of breast. Scattering images derived from the diffusion theory are also applied for lesion detection and characterization. Cancers are identified in intensity images at short wavelengths, due to the high blood content, while cysts are typically characterized by low scattering at all wavelengths. The increase (from 4 to 7) in the number of wavelengths as compared to the previous versions of the instrument aims at improving the robustness of the fitting procedures for a better estimate of tissue composition and structure and of physiological parameters. Moreover, the new wavelengths contribute to the qualitatively identify tissue composition from intensity images, and could assist lesion detection.

Multi-wavelength time-resolved optical mammography

2004 ◽  
Author(s):  
P. Taroni ◽  
L. Pallaro ◽  
A. Pifferi ◽  
L. Spinelli ◽  
A. Torricelli ◽  
...  
Keyword(s):  
Time Resolved ◽  
Optical Mammography ◽  
Multi Wavelength

Bulk optical properties and tissue components in the female breast from multiwavelength time-resolved optical mammography

2004 ◽  
Vol 9 (6) ◽  
pp. 1137 ◽  
Author(s):  
Lorenzo Spinelli ◽  
Alessandro Torricelli ◽  
Antonio Pifferi ◽  
Paola Taroni ◽  
Gian Maria Danesini ◽  
...  
Keyword(s):  
Optical Properties ◽  
Time Resolved ◽  
Optical Mammography ◽  
Female Breast

scholarly journals Design and Analysis of a Continuous and Non-Invasive Multi-Wavelength Optical Sensor for Measurement of Dermal Water Content

Sensors ◽  
2021 ◽  
Vol 21 (6) ◽  
pp. 2162
Author(s):  
Mohammad Mamouei ◽  
Subhasri Chatterjee ◽  
Meysam Razban ◽  
Meha Qassem ◽  
Panayiotis A. Kyriacou
Keyword(s):  
Water Content ◽  
Optical Sensor ◽  
Broad Band ◽  
Gravimetric Analysis ◽  
Skin Damage ◽  
Biophysical Parameter ◽  
Non Invasive ◽  
Multi Wavelength ◽  
Invasive Measurement

Dermal water content is an important biophysical parameter in preserving skin integrity and preventing skin damage. Traditional electrical-based and open-chamber evaporimeters have several well-known limitations. In particular, such devices are costly, sizeable, and only provide arbitrary outputs. They also do not permit continuous and non-invasive monitoring of dermal water content, which can be beneficial for various consumer, clinical, and cosmetic purposes. We report here on the design and development of a digital multi-wavelength optical sensor that performs continuous and non-invasive measurement of dermal water content. In silico investigation on porcine skin was carried out using the Monte Carlo modeling strategy to evaluate the feasibility and characterize the sensor. Subsequently, an in vitro experiment was carried out to evaluate the performance of the sensor and benchmark its accuracy against a high-end, broad band spectrophotometer. Reference measurements were made against gravimetric analysis. The results demonstrate that the developed sensor can deliver accurate, continuous, and non-invasive measurement of skin hydration through measurement of dermal water content. Remarkably, the novel design of the sensor exceeded the performance of the high-end spectrophotometer due to the important denoising effects of temporal averaging. The authors believe, in addition to wellbeing and skin health monitoring, the designed sensor can particularly facilitate disease management in patients presenting diabetes mellitus, hypothyroidism, malnutrition, and atopic dermatitis.

scholarly journals Six-year source apportionment of submicron organic aerosols from near-continuous measurements at SIRTA (Paris area, France)

2019 ◽  
Author(s):  
Yunjiang Zhang ◽  
Olivier Favez ◽  
Jean-Eudes Petit ◽  
Francesco Canonaco ◽  
Francois Truong ◽  
...  
Keyword(s):  
Source Apportionment ◽  
Biomass Burning ◽  
Ambient Air ◽  
Carbonaceous Aerosols ◽  
Time Resolved ◽  
Pronounced Increase ◽  
Paris Area ◽  
Multi Wavelength ◽  
High Concentrations

Abstract. Organic aerosol (OA) particles are recognized as key factors influencing air quality and climate change. However, highly-time resolved year-round characterizations of their composition and sources in ambient air are still very limited due to challenging continuous observations. Here, we present an analysis of long-term variability of submicron OA using the combination of Aerosol Chemical Speciation Monitor (ACSM) and multi-wavelength aethalometer from November 2011 to March 2018 at a background site of the Paris region (France). Source apportionment of OA was achieved via partially constrained positive matrix factorization (PMF) using the multilinear engine (ME-2). Two primary OA (POA) and two oxygenated OA (OOA) factors were identified and quantified over the entire studied period. POA factors were designated as hydrocarbon-like OA (HOA) and biomass burning OA (BBOA). The latter factor presented a significant seasonality with higher concentrations in winter with significant monthly contributions to OA (18–33 %) due to enhanced residential wood burning emissions. HOA mainly originated from traffic emissions but was also influenced by biomass burning in cold periods. OOA factors were distinguished between their less- and more-oxidized fractions (LO-OOA and MO-OOA, respectively). These factors presented distinct seasonal patterns, associated with different atmospheric formation pathways. A pronounced increase of LO-OOA concentrations and contributions (50–66 %) was observed in summer, which may be mainly explained by secondary OA (SOA) formation processes involving biogenic gaseous precursors. Conversely high concentrations and OA contributions (32–62 %) of MO-OOA during winter and spring seasons were partly associated with anthropogenic emissions and/or long-range transport from northeastern Europe. The contribution of the different OA factors as a function of OA mass loading highlighted the dominant roles of POA during pollution episodes in fall and winter, and of SOA for highest springtime and summertime OA concentrations. Finally, long-term trend analyses indicated a decreasing feature (of about 200 ng m−3 yr−1) for MO-OOA, very limited or insignificant decreasing trends for primary anthropogenic carbonaceous aerosols (BBOA and HOA, along with the fossil fuel and biomass burning black carbon components), and no trend for LO-OOA over the 6+-year investigated period.

A phosphorescent Ir(iii) complex with formamide for the luminescence determination of low-level water content in organic solvents

2016 ◽  
Vol 4 (25) ◽  
pp. 6110-6116 ◽  
Author(s):  
Song Guo ◽  
Yun Ma ◽  
Shujuan Liu ◽  
Qi Yu ◽  
Aqiang Xu ◽  
...  
Keyword(s):  
Water Content ◽  
Organic Solvents ◽  
Time Resolved ◽  
Low Level

A novel formamide-containing Ir(iii) complex was designed and synthesized for the determination of water content with low LOD and LOQ by a time-resolved luminescence technique.

Development of optical mammography based on analysis of time-resolved photon path distribution

2010 ◽  
Author(s):  
Y. Ueda ◽  
D. Yamashita ◽  
K. Yoshimoto ◽  
E. Ohmae ◽  
T. Suzuki ◽  
...  
Keyword(s):  
Time Resolved ◽  
Optical Mammography ◽  
Photon Path
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