A Diode Laser-Based Singlet Oxygen Monitor for Photodynamic Therapy; in- vitro and in- vivo Studies

2006 ◽  
Author(s):  
Seonkyung Lee ◽  
Danthu H. Vu ◽  
Michael F. Hinds ◽  
Steven J. Davis ◽  
Tayyaba Hasan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Diode Laser ◽  
In Vivo Studies ◽  
Oxygen Monitor

scholarly journals Errata: Pulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats

2009 ◽  
Vol 14 (1) ◽  
pp. 019801
Author(s):  
Seonkyung Lee ◽  
Danthu H. Vu ◽  
Michael F. Hinds ◽  
Steven J. Davis ◽  
Alvin Liang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Diode Laser ◽  
In Vivo Studies ◽  
Oxygen Monitor

scholarly journals Pulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats

2008 ◽  
Vol 13 (6) ◽  
pp. 064035 ◽  
Author(s):  
Seonkyung Lee ◽  
Danthu H. Vu ◽  
Michael F. Hinds ◽  
Steven J. Davis ◽  
Alvin Liang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Diode Laser ◽  
In Vivo Studies ◽  
Oxygen Monitor

The influence of photodynamic therapy parameters on the inactivation of Candida spp: in vitro and in vivo studies

Laser Physics ◽  
2014 ◽  
Vol 24 (4) ◽  
pp. 045601 ◽  
Author(s):  
F Alves ◽  
E G Mima ◽  
L N Dovigo ◽  
V S Bagnato ◽  
J H Jorge ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
In Vivo Studies ◽  
Candida Spp

Sodium 3-mercaptopropanesulphonate substituted phthalocyanine: Synthesis, photophysical properties, in vitro and in vivo PDT efficacy

2020 ◽  
pp. A-E
Author(s):  
Mack Biyiklioglu
Keyword(s):  
Tumor Growth ◽  
Singlet Oxygen ◽  
Hepg2 Cells ◽  
Photophysical Properties ◽  
Clinical Applications ◽  
In Vivo Studies ◽  
Cremophor El ◽  
Photochemical Properties

A new sulfonic zinc(II) phthalocyanine bearing sodium 3-mercaptopropanesulphonate (Pc) was synthesized and characterized, as to its photophysical and photochemical properties, in vitro and in vivo. Pc remain non-aggregated in [Formula: see text],[Formula: see text]-dimethylformamide and in water containing 0.1% Cremophor EL, with high singlet oxygen efficacy. In vitro studies showed that the IC[Formula: see text] value of Pc on HepG2 cells was 1.3 [Formula: see text]M. In addition, in vivo studies showed that Pc mainly accumulated in tumor sites and showed an obvious PDT effect, and ca.97% of tumor growth was inhibited. Therefore, the Pc could be applied as a very promising photosensitizer for PDT in future clinical applications.

scholarly journals Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies

2015 ◽  
Vol 99 (9) ◽  
pp. 4031-4043 ◽  
Author(s):  
Mariusz Grinholc ◽  
Joanna Nakonieczna ◽  
Grzegorz Fila ◽  
Aleksandra Taraszkiewicz ◽  
Anna Kawiak ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Photodynamic Therapy ◽  
In Vivo Studies ◽  
Antimicrobial Photodynamic Therapy

scholarly journals Sonodynamic and sono-photodynamic therapy in oncology

2019 ◽  
Vol 8 (2) ◽  
pp. 31-46
Author(s):  
D. A. Tzerkovsky ◽  
E. L. Protopovich ◽  
D. S. Stupak
Keyword(s):  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Pulse Frequency ◽  
Antitumor Efficacy ◽  
In Vivo Studies ◽  
Malignant Neoplasms ◽  
Serious Adverse Events ◽  
Treatment Methods

In the present publication, authors have analyzed the results of using sonodynamic and sono-photodynamic therapy with photosensitizing agents of various classes (hematoporphyrin, 5-aminolevulinic acid, chlorin derivatives, etc.) in experimental oncology. In a number of in vitro and in vivo studies, the high antitumor efficacy of the above treatment methods has been proven. Ultrasonic treatment with a pulse frequency of 1–3 MHz and an intensity of 0.7 to 5 W/cm2 , independently and in combination with photo-irradiation of experimental tumors, can significantly improve the cytotoxic properties of photosensitizers. This became the basisfor testing the methodsin patients with malignant neoplasms of various localizations. Scientists fromSouth-East Asia presented the preliminary results of the use of sonodynamic and sono-photodynamic therapy with photosensitizers in the treatment of malignant pathology of the mammary gland, stomach, esophagus, prostate, lung and brain. Analysis of the obtained data indicates the absence of serious adverse events and an increase in the antitumor efficacy of treatment, which included these treatment methods with chlorin-type photosensitizers. 

scholarly journals Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies

2004 ◽  
Vol 90 (8) ◽  
pp. 1660-1665 ◽  
Author(s):  
C Perotti ◽  
H Fukuda ◽  
G DiVenosa ◽  
A J MacRobert ◽  
A Batlle ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
In Vivo Studies ◽  
Porphyrin Synthesis
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