Full-Field Spectral-Domain Optical Coherence Microscopy for Snapshot Three-Dimensional Imaging

Author(s):  
Rishyashring R. Iyer ◽  
Mantas Zurauskas ◽  
Qi Cui ◽  
Liang Gao ◽  
R. Theodore Smith ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0181676 ◽  
Author(s):  
Séverine Coquoz ◽  
Paul J. Marchand ◽  
Arno Bouwens ◽  
Laurent Mouchiroud ◽  
Vincenzo Sorrentino ◽  
...  

2002 ◽  
Vol 208 (3) ◽  
pp. 177-189 ◽  
Author(s):  
A. Reeves ◽  
R. L. Parsons ◽  
J. W. Hettinger ◽  
J. I. Medford

2012 ◽  
Vol 20 (19) ◽  
pp. 21385 ◽  
Author(s):  
Christophe Pache ◽  
Noelia L. Bocchio ◽  
Arno Bouwens ◽  
Martin Villiger ◽  
Corinne Berclaz ◽  
...  

2019 ◽  
Vol 9 (2) ◽  
pp. 216 ◽  
Author(s):  
Manabu Sato ◽  
Kai Eto ◽  
Junpei Masuta ◽  
Kenji Inoue ◽  
Reiko Kurotani ◽  
...  

We demonstrate full-field optical coherence microscopy (OCM) using an ultrathin forward-imaging short multimode fiber (SMMF) probe with a core diameter of 50 μm, outer diameter of 125 μm, and length of 7.4 mm, which is a typical graded-index multimode fiber used for optical communications. The axial and lateral resolutions were measured to be 2.14 μm and 2.3 μm, respectively. By inserting the SMMF 4 mm into the cortex of an in vivo rat brain, scanning was performed to a depth of 147 μm from the SMMF facet with a field of view of 47 μm. Three-dimensional (3D) OCM images were obtained at depths ranging from approximately 20 μm to 90 μm. Based on the morphological information of the resliced 3D images and the dependence of the integration of the OCM image signal on the insertion length, the obtained 3D information of nerve fibers has been presented.


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