Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

Ashish Lal; Marshall P. Thomas; Gabriel Altschuler; Francisco Navarro; Elizabeth O'Day; Xiao Ling Li; Carla Concepcion; Yoon-Chi Han; Jerome Thiery; Danielle K. Rajani; Aaron Deutsch; Oliver Hofmann; Andrea Ventura; Winston Hide; Judy Lieberman

doi:10.1371/journal.pgen.1002363

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

PLoS Genetics ◽

10.1371/journal.pgen.1002363 ◽

2011 ◽

Vol 7 (11) ◽

pp. e1002363 ◽

Cited By ~ 149

Author(s):

Ashish Lal ◽

Marshall P. Thomas ◽

Gabriel Altschuler ◽

Francisco Navarro ◽

Elizabeth O'Day ◽

...

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Growth Factor Signaling

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Faculty Opinions recommendation of The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4628967.4506070 ◽

2010 ◽

Author(s):

Peter Downes ◽

Nicholas Leslie

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Negative Regulation ◽

Regulatory Subunit ◽

Growth Factor Signaling ◽

Phosphoinositide 3 Kinase ◽

Regulation Of Growth

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Tumor Suppressor Mutations and Growth Factor Signaling in the Pathogenesis of NF1-Associated Peripheral Nerve Sheath Tumors

Journal of Neuropathology & Experimental Neurology ◽

10.1093/jnen/64.1.1 ◽

2005 ◽

Vol 64 (1) ◽

pp. 1-9 ◽

Cited By ~ 30

Author(s):

Steven L. Carroll ◽

Mark S. Stonecypher

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Peripheral Nerve ◽

Growth Factor Signaling ◽

Nerve Sheath Tumors ◽

Peripheral Nerve Sheath Tumors ◽

Suppressor Mutations ◽

Nerve Sheath

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The Phosphoinositide 3-Kinase Regulatory Subunit p85α Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling

Cancer Research ◽

10.1158/0008-5472.can-09-3399 ◽

2010 ◽

Vol 70 (13) ◽

pp. 5305-5315 ◽

Cited By ~ 88

Author(s):

Cullen M. Taniguchi ◽

Jonathon Winnay ◽

Tatsuya Kondo ◽

Roderick T. Bronson ◽

Alexander R. Guimaraes ◽

...

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Negative Regulation ◽

Regulatory Subunit ◽

Growth Factor Signaling ◽

Phosphoinositide 3 Kinase ◽

Regulation Of Growth

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Tumor Suppressor Mutations and Growth Factor Signaling in the Pathogenesis of NF1-Associated Peripheral Nerve Sheath Tumors. I. The Role of Tumor Suppressor Mutations

Journal of Neuropathology & Experimental Neurology ◽

10.1093/jnen/63.11.1115 ◽

2004 ◽

Vol 63 (11) ◽

pp. 1115-1123 ◽

Cited By ~ 17

Author(s):

Steven L. Carroll ◽

Mark S. Stonecypher

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Peripheral Nerve ◽

Growth Factor Signaling ◽

Nerve Sheath Tumors ◽

Peripheral Nerve Sheath Tumors ◽

Suppressor Mutations ◽

Nerve Sheath

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Antiangiogenic Therapies Targeting the Vascular Endothelia Growth Factor Signaling System

Critical Reviews™ in Oncogenesis ◽

10.1615/critrevoncog.v17.i1.50 ◽

2012 ◽

Vol 17 (1) ◽

pp. 51-67 ◽

Cited By ~ 28

Author(s):

Jeanne Tie ◽

Jayesh Desai

Keyword(s):

Growth Factor ◽

Growth Factor Signaling ◽

Signaling System ◽

Antiangiogenic Therapies ◽

Vascular Endothelia

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Faculty Opinions recommendation of Nerve growth factor signaling regulates motility and docking of axonal mitochondria.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020545.242476 ◽

2004 ◽

Author(s):

Alain Prochiantz

Keyword(s):

Nerve Growth Factor ◽

Growth Factor ◽

Growth Factor Signaling ◽

Nerve Growth

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Faculty Opinions recommendation of The statistical mechanics of complex signaling networks: nerve growth factor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1116304.572309 ◽

2008 ◽

Author(s):

Hans van Beek

Keyword(s):

Nerve Growth Factor ◽

Growth Factor ◽

Statistical Mechanics ◽

Signaling Networks ◽

Growth Factor Signaling ◽

Nerve Growth ◽

Complex Signaling

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Faculty Opinions recommendation of The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11375956.13315054 ◽

2011 ◽

Author(s):

Søren Sheikh

Keyword(s):

Growth Factor ◽

Growth Factor Signaling ◽

Inhibition Of Growth

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Faculty Opinions recommendation of Beyond thermodynamics: drug binding kinetics could influence epidermal growth factor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165980.627143 ◽

2009 ◽

Author(s):

Wolfgang Jahnke

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Drug Binding ◽

Binding Kinetics ◽

Growth Factor Signaling ◽

Epidermal Growth Factor Signaling ◽

Epidermal Growth

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Faculty Opinions recommendation of MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717957529.793461935 ◽

2012 ◽

Author(s):

Paul Evans ◽

Jovana Serbanovic-Canic

Keyword(s):

Vascular Endothelial Growth Factor ◽

Endothelial Cells ◽

Growth Factor ◽

Growth Factor Signaling ◽

Vascular Endothelial ◽

Human Endothelial Cells ◽

Endothelial Growth Factor

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