scholarly journals Phylogenetic and Evolutionary Patterns in Microbial Carotenoid Biosynthesis Are Revealed by Comparative Genomics

PLoS ONE ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. e11257 ◽  
Author(s):  
Jonathan L. Klassen
Keyword(s):  
Comparative Genomics ◽  
Carotenoid Biosynthesis ◽  
Evolutionary Patterns

scholarly journals Elevated Evolutionary Rates among Functionally Diverged Reproductive Genes across Deep Vertebrate Lineages

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Christopher J. Grassa ◽  
Rob J. Kulathinal
Keyword(s):  
Gene Ontology ◽  
Comparative Genomics ◽  
Danio Rerio ◽  
Mus Musculus ◽  
Functional Divergence ◽  
Anolis Carolinensis ◽  
Egg Laying ◽  
Reproductive Systems ◽  
Evolutionary Patterns ◽  
Reproductive Genes

Among closely related taxa, proteins involved in reproduction generally evolve more rapidly than other proteins. Here, we apply a functional and comparative genomics approach to compare functional divergence across a deep phylogenetic array of egg-laying and live-bearing vertebrate taxa. We aligned and annotated a set of 4,986 1 : 1 : 1 : 1 : 1 orthologs in Anolis carolinensis (green lizard), Danio rerio (zebrafish), Xenopus tropicalis (frog), Gallus gallus (chicken), and Mus musculus (mouse) according to function using ESTs from available reproductive (including testis and ovary) and non-reproductive tissues as well as Gene Ontology. For each species lineage, genes were further classified as tissue-specific (found in a single tissue) or tissue-expressed (found in multiple tissues). Within independent vertebrate lineages, we generally find that gonadal-specific genes evolve at a faster rate than gonadal-expressed genes and significantly faster than non-reproductive genes. Among the gonadal set, testis genes are generally more diverged than ovary genes. Surprisingly, an opposite but nonsignificant pattern is found among the subset of orthologs that remained functionally conserved across all five lineages. These contrasting evolutionary patterns found between functionally diverged and functionally conserved reproductive orthologs provide evidence for pervasive and potentially cryptic lineage-specific selective processes on ancestral reproductive systems in vertebrates.

scholarly journals Bioinformatics of Metalloproteins and Metalloproteomes

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3366
Author(s):  
Yan Zhang ◽  
Junge Zheng
Keyword(s):  
Comparative Genomics ◽  
Metal Binding ◽  
Computational Prediction ◽  
Bioinformatic Analysis ◽  
Research Progress ◽  
Evolutionary Patterns ◽  
Cellular Processes ◽  
Metal Binding Sites ◽  
Domains Of Life ◽  
Systematic Understanding

Trace metals are inorganic elements that are required for all organisms in very low quantities. They serve as cofactors and activators of metalloproteins involved in a variety of key cellular processes. While substantial effort has been made in experimental characterization of metalloproteins and their functions, the application of bioinformatics in the research of metalloproteins and metalloproteomes is still limited. In the last few years, computational prediction and comparative genomics of metalloprotein genes have arisen, which provide significant insights into their distribution, function, and evolution in nature. This review aims to offer an overview of recent advances in bioinformatic analysis of metalloproteins, mainly focusing on metalloprotein prediction and the use of different metals across the tree of life. We describe current computational approaches for the identification of metalloprotein genes and metal-binding sites/patterns in proteins, and then introduce a set of related databases. Furthermore, we discuss the latest research progress in comparative genomics of several important metals in both prokaryotes and eukaryotes, which demonstrates divergent and dynamic evolutionary patterns of different metalloprotein families and metalloproteomes. Overall, bioinformatic studies of metalloproteins provide a foundation for systematic understanding of trace metal utilization in all three domains of life.

Evolutionary Patterns of Retinal-Binding Pockets of Type I Rhodopsins and Their Functions†

2006 ◽  
Vol 82 (6) ◽  
pp. 1426 ◽  
Author(s):  
Larisa Adamian ◽  
Zheng Ouyang ◽  
Yan Yuan Tseng ◽  
Jie Liang
Keyword(s):  
Type I ◽  
Evolutionary Patterns ◽  
Binding Pockets

Comparative Analysis of Genetic and Morphological Variation within the Platanthera hyperborea Complex (Orchidaceae)

2020 ◽  
Vol 45 (4) ◽  
pp. 767-778
Author(s):  
Eranga Wettewa ◽  
Nick Bailey ◽  
Lisa E. Wallace
Keyword(s):  
North America ◽  
Diploid Species ◽  
Morphological Characters ◽  
Evolutionary Patterns ◽  
Founding Population ◽  
Multiple Origins ◽  
Geographic Structure ◽  
Species Complexes ◽  
Nuclear Its ◽  
Cryptic Taxa

Abstract—Species complexes present considerable problems for a working taxonomy due to the presence of intraspecific variation, hybridization, polyploidy, and phenotypic plasticity. Understanding evolutionary patterns using molecular markers can allow for a more thorough assessment of evolutionary lineages than traditional morphological markers. In this study, we evaluated genetic diversity and phylogenetic patterns among taxa of the Platanthera hyperborea (Orchidaceae) complex, which includes diploid (Platanthera aquilonis) and polyploid (Platanthera hyperborea, P. huronensis, and P. convallariifolia) taxa spanning North America, Greenland, Iceland, and Asia. We found that three floral morphological characters overlap among the polyploid taxa, but the diploid species has smaller flowers. DNA sequence variation in a plastid (rpL16 intron) and a nuclear (ITS) marker indicated that at least three diploid species have contributed to the genomes of the polyploid taxa, suggesting all are of allopolyploid origin. Platanthera convallariifolia is most like P. dilatata and P. stricta, whereas P. huronensis and P. hyperborea appear to have originated from crosses of P. dilatata and P. aquilonis. Platanthera huronensis, which is found across North America, has multiple origins and reciprocal maternal parentage from the diploid species. By contrast, P. hyperborea, restricted to Greenland and Iceland, appears to have originated from a small founding population of hybrids in which P. dilatata was the maternal parent. Geographic structure was found among polyploid forms in North America. The area of Manitoba, Canada appears to be a contact zone among geographically diverse forms from eastern and western North America. Given the geographic and genetic variation found, we recommend continued recognition of four green-flowered species within this complex, but caution that there may be additional cryptic taxa within North America.

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