scholarly journals Reduction in Adiposity, β-Cell Function, Insulin Sensitivity, and Cardiovascular Risk Factors: A Prospective Study among Japanese with Obesity

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e57964 ◽  
Author(s):  
Maki Goto ◽  
Akemi Morita ◽  
Atsushi Goto ◽  
Kijo Deura ◽  
Satoshi Sasaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Insulin Sensitivity ◽  
Prospective Study ◽  
Cardiovascular Risk Factors ◽  
Cell Function ◽  
Β Cell ◽  
Β Cell Function ◽  
A Prospective Study

scholarly journals Common Risk Factors in Relatives and Spouses of Patients with Type 2 Diabetes in Developing Prediabetes

Healthcare ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1010
Author(s):  
Wei-Hao Hsu ◽  
Chin-Wei Tseng ◽  
Yu-Ting Huang ◽  
Ching-Chao Liang ◽  
Mei-Yueh Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Insulin Sensitivity ◽  
Cell Function ◽  
Diabetic Patients ◽  
Β Cell ◽  
Tyg Index ◽  
Β Cell Function

Prediabetes should be viewed as an increased risk for diabetes and cardiovascular disease. In this study, we investigated its prevalence among the relatives and spouses of patients with type 2 diabetes or risk factors for prediabetes, insulin resistance, and β-cell function. A total of 175 individuals were included and stratified into three groups: controls, and relatives and spouses of type 2 diabetic patients. We compared clinical characteristics consisting of a homeostatic model assessment for insulin resistance (HOMA-IR) and beta cell function (HOMA-β), a quantitative insulin sensitivity check index (QUICKI), and triglyceride glucose (TyG) index. After a multivariable linear regression analysis, the relative group was independently correlated with high fasting glucose, a high TyG index, and low β-cell function; the relatives and spouses were independently associated with a low QUICKI. The relatives and spouses equally had a higher prevalence of prediabetes. These study also indicated that the relatives had multiple factors predicting the development of diabetes mellitus, and that the spouses may share a number of common environmental factors associated with low insulin sensitivity.

scholarly journals A Prospective Study of Cardiovascular Risk Factors and Incident Hearing Loss in Men

2010 ◽  
Vol 120 (S3) ◽  
pp. S91-S91 ◽  
Author(s):  
Josef Shargorodsky ◽  
Sharon G. Curhan ◽  
Roland Eavey ◽  
Gary C. Curhan
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Cardiovascular Risk ◽  
Prospective Study ◽  
Cardiovascular Risk Factors ◽  
A Prospective Study
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