scholarly journals National Trends over One Decade in Hospitalization for Acute Myocardial Infarction among Spanish Adults with Type 2 Diabetes: Cumulative Incidence, Outcomes and Use of Percutaneous Coronary Intervention

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e85697 ◽  
Author(s):  
Ana Lopez-de-Andres ◽  
Rodrigo Jimenez-Garcia ◽  
Valentin Hernandez-Barrera ◽  
Isabel Jimenez-Trujillo ◽  
Carmen Gallardo-Pino ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Type 2 Diabetes ◽  
Acute Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Cumulative Incidence ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
National Trends

scholarly journals Features of energy and adipokine metabolism in patients with acute myocardial infarction and type 2 diabetes after percutaneous coronary intervention

2021 ◽  
Vol 25 (4) ◽  
pp. 599-604
Author(s):  
M. Yu. Koteliukh
Keyword(s):  
Myocardial Infarction ◽  
Type 2 Diabetes ◽  
Acute Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Control Group ◽  
Percutaneous Coronary ◽  
Group 2 ◽  
Group 1

Annotation. The study of energy and adipokine metabolism indicators for the development and course of acute myocardial infarction (AMI) with comorbidity remains relevant. The aim of the study was to determine the content of energy and adipokine metabolism in patients with myocardial infarction and ST-segment elevation depending on the presence and absence of type 2 diabetes mellitus (DM) after percutaneous coronary intervention (PCI). The study involved examination of 60 patients with AMI (Group 1) and 74 patients with AMI and type 2 diabetes (Group 2). Each group was divided into 2 subgroups according to coronary artery (CA) stenting. The control group included 20 healthy individuals. Adropin, irisin, fatty acid binding protein 4 (FABP 4), C1q / TNF-associated protein 3 (CTRP 3) were determined by enzyme-linked immunosorbent assay. All patients underwent coronary angiography. Statistical processing of the results of the study was carried out using the software package “IBM SPPS Statistics 27.0”. There was a decrease in the content of adropin, irisin and CTRP 3 and an increase in the concentration of FABP 4 on day 1 in Groups 1 and 2 compared with the control group (p˂0.05). In Groups 1 and 2 on day 14 there was an increase in the concentration of adropin by 23.87% and 41.43%, irisin by 56.59% and 11.11%, CTRP3 by 11.59% and 20.01% compared to day 1 (p<0.05). The level of FABP 4 in Groups 1 and 2 decreased by 19.69% and 26.61% compared to day 1 (p <0.05). In Group 1, an inverse correlation was found between Syntax Score (SS) and adropin (r= -0.432, p=0.01), irisin (r= -0.478, p<0.01), CTRP 3 (r= - 0.473, p<0.01) and a positive correlation between SS and FABP 4 (r= 0.436, p<0.05). In Group 2, there was an inverse relationship between SS and adropin (r= -0.452, p<0.05), irisin (r= -0.458, p<0.05), CTRP 3 (r= -0.437, p<0.05) and the direct relationship between SS and FABP 4 (FABP 4 (r= 0.418, p<0.05). Thus, the peculiarities of the content of energy and adipokine metabolism indicators in patients with AMI with existing and absent type 2 diabetes before and after primary CA stenting were studied.

Increasing the Penetration of Primary Angioplasty in Europe

2012 ◽  
Vol 8 (1) ◽  
pp. 60 ◽  
Author(s):  
Zuzana Kaifoszova ◽  
Petr Widimsky ◽  
◽  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Treatment Guidelines ◽  
Coronary Intervention ◽  
Reperfusion Therapy ◽  
Success Factor ◽  
The Balkans ◽  
Life Saving ◽  
Percutaneous Coronary

Primary percutaneous coronary intervention (PPCI) is recommended by the European Society of Cardiology (ESC) treatment guidelines as the preferred treatment for ST-elevation acute myocardial infarction (STEMI) whenever it is available within 90–120 minutes of the first medical contact. A survey conducted in 2008 in 51 ESC countries found that the annual incidence of hospital admissions for acute myocardial infarction is around 1,900 patients per million population, with an incidence of STEMI of about 800 per million. It showed that STEMI patients’ access to reperfusion therapy and the use of PPCI or thrombolysis (TL) vary considerably between countries. Northern, western and central Europe already have well-developed PPCI services, offering PPCI to 60–90 % of all STEMI patients. Southern Europe and the Balkans are still predominantly using TL. Where this is the case, a higher proportion of patients are left without any reperfusion treatment. The survey concluded that a nationwide PPCI strategy results in more patients being offered reperfusion therapy. To address the inequalities in STEMI patients’ access to life-saving PPCI, and to support the implementation of the ESC STEMI treatment guidelines in Europe, the Stent for Life (SFL) Initiative was launched jointly by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and EuroPCR in 2008. National cardiac societies from Bulgaria, France, Greece, Serbia, Spain and Turkey signed the SFL Declaration at the ESC Congress in Barcelona in 2009. The aim of the SFL Initiative is to improve the delivery of, and STEMI patients’ access to, life-saving PPCI and thereby reduce mortality and morbidity. Currently, 10 national cardiac societies support the SFL Initiative in their respective countries. SFL national action programmes have been developed and are being implemented in several countries. The formation of regional PPCI networks involving emergency medical services, non-percutaneous coronary intervention hospitals and PPCI centres is considered to be a critical success factor in implementing PPCI services effectively. This article describes examples of how SFL countries are progressing in implementing their national programmes, thus increasing PPCI penetration in Europe.

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