scholarly journals Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0148400 ◽  
Author(s):  
Sook-In Jung ◽  
Jong Hee Shin ◽  
Soo Hyun Kim ◽  
Jin Kim ◽  
Joo Hee Kim ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Multilocus Sequence Typing ◽  
Clinical Characteristics

scholarly journals Comparison of Microsatellite Length Polymorphism and Multilocus Sequence Typing for DNA-Based Typing of Candida albicans

2007 ◽  
Vol 45 (12) ◽  
pp. 3958-3963 ◽  
Author(s):  
D. Garcia-Hermoso ◽  
O. Cabaret ◽  
G. Lecellier ◽  
M. Desnos-Ollivier ◽  
D. Hoinard ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Length Polymorphism ◽  
Multilocus Sequence Typing ◽  
Microsatellite Length Polymorphism

scholarly journals Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland

Infection ◽  
2020 ◽  
Vol 48 (5) ◽  
pp. 761-766 ◽  
Author(s):  
A. T. Coste ◽  
◽  
A. Kritikos ◽  
J. Li ◽  
N. Khanna ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Clinical Characteristics ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy ◽  
Persistent Candidemia ◽  
Echinocandin Resistance ◽  
Overall Mortality

Abstract Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In this study, we report the emergence of FKS-mutant Candida albicans/glabrata in Switzerland and provide the microbiological and clinical characteristics of 9 candidemic episodes. All patients were previously exposed to echinocandins (median 26 days; range 15–77). Five patients received initial echinocandin therapy with persistent candidemia in 4 of them. Overall mortality was 33%.

Association between CAI microsatellite, multilocus sequence typing, and clinical significance within Candida albicans isolates

2020 ◽  
Author(s):  
Yen-Mu Wu ◽  
Chih-Hua Lee ◽  
Yi-Chuan Cheng ◽  
Jang-Jih Lu ◽  
Shao-Hung Wang
Keyword(s):  
Risk Factors ◽  
Candida Albicans ◽  
Clinical Significance ◽  
Multilocus Sequence Typing ◽  
Molecular Phylogenetics ◽  
Good Alternative ◽  
Epidemiological Studies ◽  
Chang Gung Memorial Hospital ◽  
Strain Typing ◽  
Clinical Scenario

Abstract Candida albicans bloodstream infection (BSI) is epidemiologically important because of its increasing frequency and serious outcome. Strain typing and delineation of the species are essential for understanding the phylogenetic relationship and clinical significance. Microsatellite CAI genotyping and multilocus sequence typing (MLST) were performed on 285 C. albicans bloodstream isolates from patients in Chang Gung Memorial Hospital at Linkou (CGMHL), Taiwan from 2003 to 2011. Data regarding demographics, comorbidities, risk factors, and clinical outcomes were recorded within adult patients with C. albicans BSI. Both CAI genotyping and MLST yielded comparable discriminatory power for C. albicans characterization. Besides, the distribution of CAI repetition showed a satisfactory phylogenetic association, which could be a good alternative method in the molecular phylogenetics of C. albicans and epidemiological studies. As for the clinical scenario, clade 17 isolates with CAI alleles either possessing 29 or more repetitions were related to higher 14-day and 30-day mortality, and shorter median survival days.

scholarly journals Multilocus sequence typing for the analysis of clonality among Candida albicans strains from a neonatal intensive care unit

2014 ◽  
Vol 52 (6) ◽  
pp. 653-658 ◽  
Author(s):  
Eun Song Song ◽  
Jong Hee Shin ◽  
Hee-Chang Jang ◽  
Min Ji Choi ◽  
Soo Hyun Kim ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Candida Albicans ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Multilocus Sequence Typing ◽  
Neonatal Intensive Care

scholarly journals Multilocus sequence typing of serial Candida albicans isolates from children with cancer, children with cystic fibrosis and healthy controls

2012 ◽  
Vol 50 (6) ◽  
pp. 619-626 ◽  
Author(s):  
Karianne Wiger Gammelsrud ◽  
Belinda Langnes Lindstad ◽  
Peter Gaustad ◽  
André Ingebretsen ◽  
E. Arne Høiby ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Candida Albicans ◽  
Multilocus Sequence Typing ◽  
Healthy Controls ◽  
Children With Cancer

scholarly journals Particular Candida albicans Strains in the Digestive Tract of Dyspeptic Patients, Identified by Multilocus Sequence Typing

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35311 ◽  
Author(s):  
Yan-Bing Gong ◽  
Jian-Ling Zheng ◽  
Bo Jin ◽  
De-Xiang Zhuo ◽  
Zhu-Qing Huang ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Digestive Tract ◽  
Multilocus Sequence Typing
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