scholarly journals Clinical Impact of MALDI-TOF MS Identification and Rapid Susceptibility Testing on Adequate Antimicrobial Treatment in Sepsis with Positive Blood Cultures

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0156299 ◽  
Author(s):  
Alexia Verroken ◽  
Lydwine Defourny ◽  
Olivier le Polain de Waroux ◽  
Leïla Belkhir ◽  
Pierre-François Laterre ◽  
...  
Keyword(s):  
Susceptibility Testing ◽  
Antimicrobial Treatment ◽  
Blood Cultures ◽  
Clinical Impact ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

scholarly journals Correction: Clinical Impact of MALDI-TOF MS Identification and Rapid Susceptibility Testing on Adequate Antimicrobial Treatment in Sepsis with Positive Blood Cultures

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0160537 ◽  
Author(s):  
Alexia Verroken ◽  
Lydwine Defourny ◽  
Olivier le Polain de Waroux ◽  
Leïla Belkhir ◽  
Pierre-François Laterre ◽  
...  
Keyword(s):  
Susceptibility Testing ◽  
Antimicrobial Treatment ◽  
Blood Cultures ◽  
Clinical Impact ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

scholarly journals Rapid antibiotic susceptibility testing on blood cultures using MALDI-TOF MS

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205603 ◽  
Author(s):  
Marlène Sauget ◽  
Xavier Bertrand ◽  
Didier Hocquet
Keyword(s):  
Antibiotic Susceptibility ◽  
Susceptibility Testing ◽  
Blood Cultures ◽  
Antibiotic Susceptibility Testing ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

scholarly journals Short Incubation of Positive Blood Cultures on Solid Media for Species Identification by MALDI-TOF MS: Which Agar Is the Fastest?

2021 ◽  
Author(s):  
Neele J. Froböse ◽  
Evgeny A. Idelevich ◽  
Frieder Schaumburg
Keyword(s):  
Mass Spectrometry ◽  
Species Identification ◽  
Susceptibility Testing ◽  
Solid Medium ◽  
Blood Cultures ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Solid Media ◽  
Laboratory Results ◽  
Tof Ms

When blood cultures are flagged as positive, they are incubated on solid media to produce enough biomass of the bacterium for identification and susceptibility testing. Rapid turnaround times for laboratory results could save lives, and we wanted to assess which solid medium is best to shorten the time to species identification using MALDI-TOF mass spectrometry.

scholarly journals Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization

2017 ◽  
Vol 55 (12) ◽  
pp. 3328-3338 ◽  
Author(s):  
Matthew L. Faron ◽  
Blake W. Buchan ◽  
Nathan A. Ledeboer
Keyword(s):  
Mass Spectrometry ◽  
Susceptibility Testing ◽  
Time Of Flight ◽  
Blood Cultures ◽  
Ionization Time ◽  
Maldi Tof Ms ◽  
Desorption Ionization ◽  
Maldi Tof ◽  
Flight Mass Spectrometry ◽  
Tof Ms

ABSTRACTEarly initiation of effective antibiotics for septic patients is essential for patient survival. Matrix-assisted desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has revolutionized clinical microbiology for isolate identification and has the possibility to impact how blood culture testing is performed. This review discusses the various uses of MALDI-TOF MS for the identification and susceptibility testing of positive blood cultures, the performance of these methods, and the outcomes involved with its implementation.

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